IMP

Process View

Homo sapiens

3 genes annotated in human

nitrogen cycle metabolic process

GO:0071941

A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nitrogen cycle metabolic process"

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Name	Description	Probability	Func Analog Organism
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	1.000
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.976
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.962	Human
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.779
ADH6	alcohol dehydrogenase 6 (class V)	0.768
TADA3	transcriptional adaptor 3	0.522
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.463	Human
OTC	ornithine carbamoyltransferase	0.440
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.379	Human
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.301
AGXT2	alanine--glyoxylate aminotransferase 2	0.275
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.226
MAT1A	methionine adenosyltransferase I, alpha	0.212
CYP2D6	cytochrome P450, family 2, subfamily D, polypeptide 6	0.194	Human
AADAC	arylacetamide deacetylase (esterase)	0.169
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.138
HAL	histidine ammonia-lyase	0.131
AFM	afamin	0.128
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.122
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.122
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.119
ALDOB	aldolase B, fructose-bisphosphate	0.113
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.110
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.101
SAA4	serum amyloid A4, constitutive	0.100
CFHR4	complement factor H-related 4	0.100
PDCD7	programmed cell death 7	0.099
MTTP	microsomal triglyceride transfer protein	0.095
FETUB	fetuin B	0.094
GLYAT	glycine-N-acyltransferase	0.093
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.086
HRG	histidine-rich glycoprotein	0.084
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.083
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.072
NCOA6	nuclear receptor coactivator 6	0.071
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.066
ELP3	elongation protein 3 homolog (S. cerevisiae)	0.061
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.061
C8B	complement component 8, beta polypeptide	0.057
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.057
CYP1A2	cytochrome P450, family 1, subfamily A, polypeptide 2	0.056
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.056
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.056
ELP2	elongation protein 2 homolog (S. cerevisiae)	0.055
FMO4	flavin containing monooxygenase 4	0.053
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.053
CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	0.053	Human
BHMT	betaine--homocysteine S-methyltransferase	0.052
FABP1	fatty acid binding protein 1, liver	0.051
FOXO1	forkhead box O1	0.051
G6PC	glucose-6-phosphatase, catalytic subunit	0.050
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.050
IRF3	interferon regulatory factor 3	0.050
XDH	xanthine dehydrogenase	0.050
POU2F1	POU class 2 homeobox 1	0.049
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.049	Human
C4BPA	complement component 4 binding protein, alpha	0.049
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.047
ADRBK1	adrenergic, beta, receptor kinase 1	0.046
ANXA10	annexin A10	0.045
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.044
F13B	coagulation factor XIII, B polypeptide	0.044
PON1	paraoxonase 1	0.044
DNM1	dynamin 1	0.044
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.044	Mouse
CHD3	chromodomain helicase DNA binding protein 3	0.043
MAST1	microtubule associated serine/threonine kinase 1	0.042
GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.042
GYS2	glycogen synthase 2 (liver)	0.041
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.041
MEP1B	meprin A, beta	0.041
TTPA	tocopherol (alpha) transfer protein	0.041
RAB3D	RAB3D, member RAS oncogene family	0.039
F11	coagulation factor XI	0.039
UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15	0.038
C6	complement component 6	0.037
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.036
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.036
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.035
HOXB7	homeobox B7	0.034
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.033	Human
LRRC31	leucine rich repeat containing 31	0.032
DNASE1L3	deoxyribonuclease I-like 3	0.031
PIPOX	pipecolic acid oxidase	0.031
APOE	apolipoprotein E	0.031
F9	coagulation factor IX	0.030
FABP2	fatty acid binding protein 2, intestinal	0.030
SP1	Sp1 transcription factor	0.030
GSTA3	glutathione S-transferase alpha 3	0.029
NCOA1	nuclear receptor coactivator 1	0.028
HNF4G	hepatocyte nuclear factor 4, gamma	0.028
ENTPD5	ectonucleoside triphosphate diphosphohydrolase 5	0.028
TM4SF4	transmembrane 4 L six family member 4	0.027
ELP4	elongation protein 4 homolog (S. cerevisiae)	0.027
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.026
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.026
FGL1	fibrinogen-like 1	0.026
C9	complement component 9	0.026
ORM2	orosomucoid 2	0.025
PAH	phenylalanine hydroxylase	0.025
GRIP1	glutamate receptor interacting protein 1	0.024
PNLIPRP1	pancreatic lipase-related protein 1	0.024
C8A	complement component 8, alpha polypeptide	0.024
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.024
ARG1	arginase, liver	0.023	Rat
CLCA4	chloride channel accessory 4	0.022
TEC	tec protein tyrosine kinase	0.022
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.022
CNGA1	cyclic nucleotide gated channel alpha 1	0.022
ASCC2	activating signal cointegrator 1 complex subunit 2	0.021
NCOA2	nuclear receptor coactivator 2	0.021
COLEC10	collectin sub-family member 10 (C-type lectin)	0.021
REG3A	regenerating islet-derived 3 alpha	0.021
EVL	Enah/Vasp-like	0.021
C4BPB	complement component 4 binding protein, beta	0.020
A1CF	APOBEC1 complementation factor	0.020
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.020
ACE2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.020
C9orf68	chromosome 9 open reading frame 68	0.020
ZDHHC17	zinc finger, DHHC-type containing 17	0.019
ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.019
SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4	0.019
HGD	homogentisate 1,2-dioxygenase	0.019
FOXO3	forkhead box O3	0.019
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.019	Human
TDO2	tryptophan 2,3-dioxygenase	0.019
ZKSCAN3	zinc finger with KRAB and SCAN domains 3	0.018
UGT1A9	UDP glucuronosyltransferase 1 family, polypeptide A9	0.018
STAT5A	signal transducer and activator of transcription 5A	0.018
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.018
ALDH4A1	aldehyde dehydrogenase 4 family, member A1	0.018
ANGPTL3	angiopoietin-like 3	0.018
UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3	0.017
APOC3	apolipoprotein C-III	0.017
CPB2	carboxypeptidase B2 (plasma)	0.017
POF1B	premature ovarian failure, 1B	0.017
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.017
HMGA1	high mobility group AT-hook 1	0.017
PLG	plasminogen	0.017
APOC4	apolipoprotein C-IV	0.017
LRRC19	leucine rich repeat containing 19	0.017
ANKRD7	ankyrin repeat domain 7	0.017
DPYS	dihydropyrimidinase	0.016
PPIL6	peptidylprolyl isomerase (cyclophilin)-like 6	0.016
SPP2	secreted phosphoprotein 2, 24kDa	0.016
LIPC	lipase, hepatic	0.016
TAT	tyrosine aminotransferase	0.016
ZFYVE19	zinc finger, FYVE domain containing 19	0.016
PON3	paraoxonase 3	0.016
APOBEC1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.016
MIA2	melanoma inhibitory activity 2	0.016
FAM164C	family with sequence similarity 164, member C	0.016
NTS	neurotensin	0.016
AKTIP	AKT interacting protein	0.016
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.016
HABP2	hyaluronan binding protein 2	0.016
FMNL2	formin-like 2	0.015
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.015
DPPA4	developmental pluripotency associated 4	0.015
MAN2A2	mannosidase, alpha, class 2A, member 2	0.015
LPA	lipoprotein, Lp(a)	0.015
CD4	CD4 molecule	0.015
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.015
ZNF717	zinc finger protein 717	0.015
GABPA	GA binding protein transcription factor, alpha subunit 60kDa	0.015
RGN	regucalcin (senescence marker protein-30)	0.015
FASLG	Fas ligand (TNF superfamily, member 6)	0.015
ETV3	ets variant 3	0.015
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.015
CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4	0.015
PLA2G1B	phospholipase A2, group IB (pancreas)	0.015
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.014
LIPF	lipase, gastric	0.014
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.014
CCDC68	coiled-coil domain containing 68	0.014
MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)	0.014
GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	0.014
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.014
TTR	transthyretin	0.014
NKAP	NFKB activating protein	0.014
F5	coagulation factor V (proaccelerin, labile factor)	0.014
APCS	amyloid P component, serum	0.014
AOC2	amine oxidase, copper containing 2 (retina-specific)	0.014
SLC38A4	solute carrier family 38, member 4	0.014
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.014
MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	0.014
CA5A	carbonic anhydrase VA, mitochondrial	0.013
ESR1	estrogen receptor 1	0.013
ANXA13	annexin A13	0.013
ZNF132	zinc finger protein 132	0.013
UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.013
ZG16	zymogen granule protein 16 homolog (rat)	0.013
MTA2	metastasis associated 1 family, member 2	0.013
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.013
REG1A	regenerating islet-derived 1 alpha	0.013
HEY2	hairy/enhancer-of-split related with YRPW motif 2	0.013
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.013
STARD5	StAR-related lipid transfer (START) domain containing 5	0.013
SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	0.013
LECT2	leukocyte cell-derived chemotaxin 2	0.013
TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)	0.013
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.013
TMPRSS6	transmembrane protease, serine 6	0.012
HPX	hemopexin	0.012
NXF3	nuclear RNA export factor 3	0.012
UGT1A7	UDP glucuronosyltransferase 1 family, polypeptide A7	0.012
MEST	mesoderm specific transcript homolog (mouse)	0.012
EPHX2	epoxide hydrolase 2, cytoplasmic	0.012
SLC19A3	solute carrier family 19, member 3	0.012
ZMAT2	zinc finger, matrin-type 2	0.012
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.012
SPO11	SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)	0.012
CFHR5	complement factor H-related 5	0.012
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.012
MTMR8	myotubularin related protein 8	0.012
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.012
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.012
PLA2G10	phospholipase A2, group X	0.012
APOF	apolipoprotein F	0.012
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.012
SGK2	serum/glucocorticoid regulated kinase 2	0.012
HIST1H3J	histone cluster 1, H3j	0.012
IMPG2	interphotoreceptor matrix proteoglycan 2	0.012
HHLA2	HERV-H LTR-associating 2	0.012
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.012
TMEM27	transmembrane protein 27	0.012
CDH17	cadherin 17, LI cadherin (liver-intestine)	0.011
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.011
RDH16	retinol dehydrogenase 16 (all-trans)	0.011
PRG4	proteoglycan 4	0.011
C10orf46	chromosome 10 open reading frame 46	0.011
TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)	0.011
GCM1	glial cells missing homolog 1 (Drosophila)	0.011
RNF32	ring finger protein 32	0.011
CFHR2	complement factor H-related 2	0.011
SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3	0.011
ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	0.011
MUC3A	mucin 3A, cell surface associated	0.011
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.011
GSTM4	glutathione S-transferase mu 4	0.011
ZNF221	zinc finger protein 221	0.011
CIDEB	cell death-inducing DFFA-like effector b	0.011
IFNA5	interferon, alpha 5	0.011
ATP10B	ATPase, class V, type 10B	0.011
TAS2R4	taste receptor, type 2, member 4	0.011
BCMO1	beta-carotene 15,15'-monooxygenase 1	0.011
LRTOMT	leucine rich transmembrane and 0-methyltransferase domain containing	0.011
NDRG2	NDRG family member 2	0.011
FGA	fibrinogen alpha chain	0.011
TM4SF20	transmembrane 4 L six family member 20	0.011
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.011
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.011
GC	group-specific component (vitamin D binding protein)	0.011
CES3	carboxylesterase 3	0.011
PRMT2	protein arginine methyltransferase 2	0.011
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.011
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.011
GSTT1	glutathione S-transferase theta 1	0.011
GYPA	glycophorin A (MNS blood group)	0.011
CDKL2	cyclin-dependent kinase-like 2 (CDC2-related kinase)	0.011
OCLM	oculomedin	0.011
BCO2	beta-carotene oxygenase 2	0.011
ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2	0.011
C5	complement component 5	0.011
UPK1B	uroplakin 1B	0.011
SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.011
TAS2R7	taste receptor, type 2, member 7	0.011
ESR2	estrogen receptor 2 (ER beta)	0.011
CPS1	carbamoyl-phosphate synthase 1, mitochondrial	0.010	Rat
OTUD7B	OTU domain containing 7B	0.010
ACADL	acyl-CoA dehydrogenase, long chain	0.010
TUT1	terminal uridylyl transferase 1, U6 snRNA-specific	0.010
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.010
SLC30A10	solute carrier family 30, member 10	0.010
APOA2	apolipoprotein A-II	0.010
HPD	4-hydroxyphenylpyruvate dioxygenase	0.010
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.010
ALDH6A1	aldehyde dehydrogenase 6 family, member A1	0.010
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	0.010
GNMT	glycine N-methyltransferase	0.010