IMP

Process View

Homo sapiens

14 genes annotated in human

Multi-species View

regulation of interleukin 1 secretion

GO:0050704

Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 1 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 1 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.705	Mouse Rat
RIPK2	receptor-interacting serine-threonine kinase 2	0.691
NLRC4	NLR family, CARD domain containing 4	0.589
HP	haptoglobin	0.296
AXL	AXL receptor tyrosine kinase	0.188
APOC1	apolipoprotein C-I	0.174
A2M	alpha-2-macroglobulin	0.167
PYCARD	PYD and CARD domain containing	0.159
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.159
IDE	insulin-degrading enzyme	0.088
CCL4	chemokine (C-C motif) ligand 4	0.071
APOC3	apolipoprotein C-III	0.068
ALB	albumin	0.060
MEFV	Mediterranean fever	0.054
TRIM22	tripartite motif containing 22	0.051
BTN3A2	butyrophilin, subfamily 3, member A2	0.044
PYDC2	pyrin domain containing 2	0.041
LCAT	lecithin-cholesterol acyltransferase	0.036
GBP1	guanylate binding protein 1, interferon-inducible	0.036
GBP2	guanylate binding protein 2, interferon-inducible	0.033
APOA2	apolipoprotein A-II	0.032
IFI16	interferon, gamma-inducible protein 16	0.032	Human
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.030	Mouse
FGA	fibrinogen alpha chain	0.029
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.029
CARD6	caspase recruitment domain family, member 6	0.029
NMI	N-myc (and STAT) interactor	0.028
CARD16	caspase recruitment domain family, member 16	0.028
BTN3A3	butyrophilin, subfamily 3, member A3	0.027
BTN3A1	butyrophilin, subfamily 3, member A1	0.026
CLEC2B	C-type lectin domain family 2, member B	0.025
ELF4	E74-like factor 4 (ets domain transcription factor)	0.021
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.020
APOC2	apolipoprotein C-II	0.020
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.019
SP100	SP100 nuclear antigen	0.019
FZD1	frizzled homolog 1 (Drosophila)	0.016
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.016
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.015
LY96	lymphocyte antigen 96	0.014
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.014
TXNDC2	thioredoxin domain containing 2 (spermatozoa)	0.013
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.013
CXCL9	chemokine (C-X-C motif) ligand 9	0.013
ANG	angiogenin, ribonuclease, RNase A family, 5	0.012
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.012
GBP5	guanylate binding protein 5	0.012
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.012
SELL	selectin L	0.012
CCL21	chemokine (C-C motif) ligand 21	0.012
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.011
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.011
LRP6	low density lipoprotein receptor-related protein 6	0.011
NLRP1	NLR family, pyrin domain containing 1	0.011
HCP5	HLA complex P5	0.011
AIM2	absent in melanoma 2	0.011
TTR	transthyretin	0.010
CTSS	cathepsin S	0.010
BCL2A1	BCL2-related protein A1	0.010