IMP

Process View

Homo sapiens

4 genes annotated in human

purinergic nucleotide receptor signaling pathway

The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "purinergic nucleotide receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "purinergic nucleotide receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.772
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.131
TRAT1	T cell receptor associated transmembrane adaptor 1	0.123
BIN2	bridging integrator 2	0.110
GZMK	granzyme K (granzyme 3; tryptase II)	0.086
SELL	selectin L	0.075
GPR18	G protein-coupled receptor 18	0.072
P2RY14	purinergic receptor P2Y, G-protein coupled, 14	0.072	Human
GIMAP4	GTPase, IMAP family member 4	0.069
CD96	CD96 molecule	0.069
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.064
ITK	IL2-inducible T-cell kinase	0.059
IFNG	interferon, gamma	0.058
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.051
CCR5	chemokine (C-C motif) receptor 5	0.047
FGL2	fibrinogen-like 2	0.043
EVI2A	ecotropic viral integration site 2A	0.039
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.036
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.034
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.032
LY86	lymphocyte antigen 86	0.032
GPR183	G protein-coupled receptor 183	0.032
RGS18	regulator of G-protein signaling 18	0.031
GPR34	G protein-coupled receptor 34	0.030	Human
NEU1	sialidase 1 (lysosomal sialidase)	0.029
CD1C	CD1c molecule	0.029
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.029
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.028	Human Rat
TLR8	toll-like receptor 8	0.028
ICOS	inducible T-cell co-stimulator	0.027
AIF1	allograft inflammatory factor 1	0.027
CD8A	CD8a molecule	0.027
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.027
MPEG1	macrophage expressed 1	0.026
GPR171	G protein-coupled receptor 171	0.026	Human
CYSLTR1	cysteinyl leukotriene receptor 1	0.025
F13A1	coagulation factor XIII, A1 polypeptide	0.025
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.025
HPGDS	hematopoietic prostaglandin D synthase	0.025
CECR1	cat eye syndrome chromosome region, candidate 1	0.025
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.025
CXCR6	chemokine (C-X-C motif) receptor 6	0.024
CPA3	carboxypeptidase A3 (mast cell)	0.023
MNDA	myeloid cell nuclear differentiation antigen	0.023
CD69	CD69 molecule	0.022
KLRF1	killer cell lectin-like receptor subfamily F, member 1	0.022
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.022
FGF6	fibroblast growth factor 6	0.022
CRTAM	cytotoxic and regulatory T cell molecule	0.022
RNASE6	ribonuclease, RNase A family, k6	0.021
STAP1	signal transducing adaptor family member 1	0.021
CD27	CD27 molecule	0.020
CLEC4A	C-type lectin domain family 4, member A	0.020
GPR65	G protein-coupled receptor 65	0.020
IRF8	interferon regulatory factor 8	0.019
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.019
ART1	ADP-ribosyltransferase 1	0.019
CLC	Charcot-Leyden crystal protein	0.018
CYTIP	cytohesin 1 interacting protein	0.018
TXK	TXK tyrosine kinase	0.018
CCR2	chemokine (C-C motif) receptor 2	0.017
TFEC	transcription factor EC	0.017
LY9	lymphocyte antigen 9	0.016
CRYBB2	crystallin, beta B2	0.016
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.016
CD86	CD86 molecule	0.016
TM6SF1	transmembrane 6 superfamily member 1	0.016
BANK1	B-cell scaffold protein with ankyrin repeats 1	0.016
TLR7	toll-like receptor 7	0.016
IPCEF1	interaction protein for cytohesin exchange factors 1	0.016
MARCH1	membrane-associated ring finger (C3HC4) 1	0.016
DPEP2	dipeptidase 2	0.016
EVI2B	ecotropic viral integration site 2B	0.016
CD84	CD84 molecule	0.015
ARHGAP15	Rho GTPase activating protein 15	0.015
SARDH	sarcosine dehydrogenase	0.015
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.015
GAB4	GRB2-associated binding protein family, member 4	0.015
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.014
BTLA	B and T lymphocyte associated	0.014
XCL2	chemokine (C motif) ligand 2	0.014
GPR82	G protein-coupled receptor 82	0.014
CXCL9	chemokine (C-X-C motif) ligand 9	0.014
CCR6	chemokine (C-C motif) receptor 6	0.014
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.014
VSIG4	V-set and immunoglobulin domain containing 4	0.013
CD2	CD2 molecule	0.013
BTK	Bruton agammaglobulinemia tyrosine kinase	0.013
IL18RAP	interleukin 18 receptor accessory protein	0.013
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.013
TNFAIP8L2	tumor necrosis factor, alpha-induced protein 8-like 2	0.013
CD160	CD160 molecule	0.012
SLAMF6	SLAM family member 6	0.012
P2RY12	purinergic receptor P2Y, G-protein coupled, 12	0.012
DHRS9	dehydrogenase/reductase (SDR family) member 9	0.012
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.012
CYTH4	cytohesin 4	0.012
KLRC4	killer cell lectin-like receptor subfamily C, member 4	0.012
AIM2	absent in melanoma 2	0.011
FPR3	formyl peptide receptor 3	0.011
CPVL	carboxypeptidase, vitellogenic-like	0.011
HVCN1	hydrogen voltage-gated channel 1	0.011
ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	0.011
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.011
ADORA3	adenosine A3 receptor	0.011
RAB33A	RAB33A, member RAS oncogene family	0.011
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.011
CCR7	chemokine (C-C motif) receptor 7	0.011
CD38	CD38 molecule	0.011
TSPAN32	tetraspanin 32	0.011
CFP	complement factor properdin	0.010
PDE3B	phosphodiesterase 3B, cGMP-inhibited	0.010
EOMES	eomesodermin	0.010
LCP1	lymphocyte cytosolic protein 1 (L-plastin)	0.010
TCL1A	T-cell leukemia/lymphoma 1A	0.010
ADRA1B	adrenergic, alpha-1B-, receptor	0.010