IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

interferon alpha biosynthetic process

GO:0045349

The chemical reactions and pathways resulting in the formation of interferon-alpha.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "interferon alpha biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "interferon alpha biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
MYD88	myeloid differentiation primary response gene (88)	1.000
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	1.000
LY96	lymphocyte antigen 96	1.000
TICAM2	toll-like receptor adaptor molecule 2	0.986
TLR1	toll-like receptor 1	0.758	Human
TLR2	toll-like receptor 2	0.732
TLR4	toll-like receptor 4	0.726	Human
RNASE6	ribonuclease, RNase A family, k6	0.550
IGSF6	immunoglobulin superfamily, member 6	0.431
BTK	Bruton agammaglobulinemia tyrosine kinase	0.388
LY86	lymphocyte antigen 86	0.357
TFEC	transcription factor EC	0.346
CCR1	chemokine (C-C motif) receptor 1	0.340
CD86	CD86 molecule	0.327
VNN2	vanin 2	0.223
P2RY13	purinergic receptor P2Y, G-protein coupled, 13	0.198
MS4A7	membrane-spanning 4-domains, subfamily A, member 7	0.188
IRAK2	interleukin-1 receptor-associated kinase 2	0.186
IRAK3	interleukin-1 receptor-associated kinase 3	0.132
EVI2A	ecotropic viral integration site 2A	0.122
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.116
SYK	spleen tyrosine kinase	0.090
FGL2	fibrinogen-like 2	0.087
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.087
CD163	CD163 molecule	0.079
MSR1	macrophage scavenger receptor 1	0.074
CTSS	cathepsin S	0.071
EVI2B	ecotropic viral integration site 2B	0.069
MARCH1	membrane-associated ring finger (C3HC4) 1	0.057
MPEG1	macrophage expressed 1	0.056
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.047
TLR6	toll-like receptor 6	0.043	Human
LRMP	lymphoid-restricted membrane protein	0.042
IRAK4	interleukin-1 receptor-associated kinase 4	0.038
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.037
BLNK	B-cell linker	0.034
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.033
CYBB	cytochrome b-245, beta polypeptide	0.033
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.032
CMIP	c-Maf-inducing protein	0.030
NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	0.028
MNDA	myeloid cell nuclear differentiation antigen	0.028
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.028
IRF8	interferon regulatory factor 8	0.028
TLR7	toll-like receptor 7	0.027
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.026
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.025
STAP2	signal transducing adaptor family member 2	0.023
DHRS9	dehydrogenase/reductase (SDR family) member 9	0.023
GPR65	G protein-coupled receptor 65	0.023
CLEC7A	C-type lectin domain family 7, member A	0.022
ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1	0.022
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.022
GPR34	G protein-coupled receptor 34	0.021
SPOP	speckle-type POZ protein	0.021
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.019
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.019
C3AR1	complement component 3a receptor 1	0.019
CYSLTR1	cysteinyl leukotriene receptor 1	0.019
C17orf60	chromosome 17 open reading frame 60	0.019
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.018
PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	0.018
FPR3	formyl peptide receptor 3	0.017
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.017
CYTIP	cytohesin 1 interacting protein	0.017
PTAFR	platelet-activating factor receptor	0.016
C13orf18	chromosome 13 open reading frame 18	0.016
CLEC4A	C-type lectin domain family 4, member A	0.015
BST1	bone marrow stromal cell antigen 1	0.015
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.014
TICAM1	toll-like receptor adaptor molecule 1	0.014
MR1	major histocompatibility complex, class I-related	0.014
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.014
SELL	selectin L	0.013
AIM2	absent in melanoma 2	0.013
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.013
SLFN12	schlafen family member 12	0.013
GPR18	G protein-coupled receptor 18	0.012
HNMT	histamine N-methyltransferase	0.012
CARD16	caspase recruitment domain family, member 16	0.012
RGS18	regulator of G-protein signaling 18	0.012
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.012
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.012
CXorf21	chromosome X open reading frame 21	0.012
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.011
C1QC	complement component 1, q subcomponent, C chain	0.011
MS4A14	membrane-spanning 4-domains, subfamily A, member 14	0.011
SIRPB1	signal-regulatory protein beta 1	0.011
APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.010
TLR8	toll-like receptor 8	0.010
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.010
F13A1	coagulation factor XIII, A1 polypeptide	0.010
IL7	interleukin 7	0.010
TLR5	toll-like receptor 5	0.010	Human
CCR2	chemokine (C-C motif) receptor 2	0.010
GIMAP4	GTPase, IMAP family member 4	0.010