IMP
Process View
The network for 'interferon alpha biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
interferon alpha biosynthetic process
The chemical reactions and pathways resulting in the formation of interferon-alpha.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| MYD88 | myeloid differentiation primary response gene (88) | 1.000 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 1.000 | |
| LY96 | lymphocyte antigen 96 | 1.000 | |
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.986 | |
| TLR1 | toll-like receptor 1 | 0.758 | |
| TLR2 | toll-like receptor 2 | 0.732 | |
| TLR4 | toll-like receptor 4 | 0.726 | |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.550 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.431 | |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.388 | |
| LY86 | lymphocyte antigen 86 | 0.357 | |
| TFEC | transcription factor EC | 0.346 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.340 | |
| CD86 | CD86 molecule | 0.327 | |
| VNN2 | vanin 2 | 0.223 | |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 0.198 | |
| MS4A7 | membrane-spanning 4-domains, subfamily A, member 7 | 0.188 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.186 | |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.132 | |
| EVI2A | ecotropic viral integration site 2A | 0.122 | |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.116 | |
| SYK | spleen tyrosine kinase | 0.090 | |
| FGL2 | fibrinogen-like 2 | 0.087 | |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4 | 0.087 | |
| CD163 | CD163 molecule | 0.079 | |
| MSR1 | macrophage scavenger receptor 1 | 0.074 | |
| CTSS | cathepsin S | 0.071 | |
| EVI2B | ecotropic viral integration site 2B | 0.069 | |
| MARCH1 | membrane-associated ring finger (C3HC4) 1 | 0.057 | |
| MPEG1 | macrophage expressed 1 | 0.056 | |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.047 | |
| TLR6 | toll-like receptor 6 | 0.043 | |
| LRMP | lymphoid-restricted membrane protein | 0.042 | |
| IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.038 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.037 | |
| BLNK | B-cell linker | 0.034 | |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.033 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.033 | |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.032 | |
| CMIP | c-Maf-inducing protein | 0.030 | |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | 0.028 | |
| MNDA | myeloid cell nuclear differentiation antigen | 0.028 | |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.028 | |
| IRF8 | interferon regulatory factor 8 | 0.028 | |
| TLR7 | toll-like receptor 7 | 0.027 | |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.026 | |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.025 | |
| STAP2 | signal transducing adaptor family member 2 | 0.023 | |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.023 | |
| GPR65 | G protein-coupled receptor 65 | 0.023 | |
| CLEC7A | C-type lectin domain family 7, member A | 0.022 | |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.022 | |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.022 | |
| GPR34 | G protein-coupled receptor 34 | 0.021 | |
| SPOP | speckle-type POZ protein | 0.021 | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.019 | |
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.019 | |
| C3AR1 | complement component 3a receptor 1 | 0.019 | |
| CYSLTR1 | cysteinyl leukotriene receptor 1 | 0.019 | |
| C17orf60 | chromosome 17 open reading frame 60 | 0.019 | |
| IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 0.018 | |
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | 0.018 | |
| FPR3 | formyl peptide receptor 3 | 0.017 | |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.017 | |
| CYTIP | cytohesin 1 interacting protein | 0.017 | |
| PTAFR | platelet-activating factor receptor | 0.016 | |
| C13orf18 | chromosome 13 open reading frame 18 | 0.016 | |
| CLEC4A | C-type lectin domain family 4, member A | 0.015 | |
| BST1 | bone marrow stromal cell antigen 1 | 0.015 | |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.014 | |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.014 | |
| MR1 | major histocompatibility complex, class I-related | 0.014 | |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.014 | |
| SELL | selectin L | 0.013 | |
| AIM2 | absent in melanoma 2 | 0.013 | |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.013 | |
| SLFN12 | schlafen family member 12 | 0.013 | |
| GPR18 | G protein-coupled receptor 18 | 0.012 | |
| HNMT | histamine N-methyltransferase | 0.012 | |
| CARD16 | caspase recruitment domain family, member 16 | 0.012 | |
| RGS18 | regulator of G-protein signaling 18 | 0.012 | |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.012 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.012 | |
| CXorf21 | chromosome X open reading frame 21 | 0.012 | |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 0.011 | |
| C1QC | complement component 1, q subcomponent, C chain | 0.011 | |
| MS4A14 | membrane-spanning 4-domains, subfamily A, member 14 | 0.011 | |
| SIRPB1 | signal-regulatory protein beta 1 | 0.011 | |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein | 0.010 | |
| TLR8 | toll-like receptor 8 | 0.010 | |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.010 | |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.010 | |
| IL7 | interleukin 7 | 0.010 | |
| TLR5 | toll-like receptor 5 | 0.010 | |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.010 | |
| GIMAP4 | GTPase, IMAP family member 4 | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.029 | |
| Pilra | paired immunoglobin-like type 2 receptor alpha | 0.028 | |
| Cd300ld | CD300 molecule-like family member d | 0.025 | |
| Fcgr4 | Fc receptor, IgG, low affinity IV | 0.024 | |
| Siglece | sialic acid binding Ig-like lectin E | 0.023 | |
| Msr1 | macrophage scavenger receptor 1 | 0.023 | |
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.021 | |
| Cd33 | CD33 antigen | 0.020 | |
| Klra2 | killer cell lectin-like receptor, subfamily A, member 2 | 0.015 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.014 | |
| Ms4a6d | membrane-spanning 4-domains, subfamily A, member 6D | 0.014 | |
| Rtp4 | receptor transporter protein 4 | 0.012 | |
| Ly6i | lymphocyte antigen 6 complex, locus I | 0.012 | |
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.011 | |
| Nmi | N-myc (and STAT) interactor | 0.011 | |
| Trim30d | tripartite motif-containing 30D | 0.011 | |
| Ifih1 | interferon induced with helicase C domain 1 | 0.011 | |
| Slamf7 | SLAM family member 7 | 0.011 | |
| Ticam1 | toll-like receptor adaptor molecule 1 | 0.011 | |
| Ifi44 | interferon-induced protein 44 | 0.010 | |
| Clec5a | C-type lectin domain family 5, member a | 0.010 | |
| Tbxas1 | thromboxane A synthase 1, platelet | 0.010 | |
| Pyhin1 | pyrin and HIN domain family, member 1 | 0.010 |