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Homo sapiens

26 genes annotated in human

lipid metabolism disorder

DOID:3146

An inhertited metabolic disorder that involves the creation and degradation of lipids.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lipid metabolism disorder"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lipid metabolism disorder" (in gray)

Name	Description	Probability	Func Analog Organism
PTPRB	protein tyrosine phosphatase, receptor type, B	0.611
FADS1	fatty acid desaturase 1	0.478
APOA1	apolipoprotein A-I	0.391	Human
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.290
ICAM1	intercellular adhesion molecule 1	0.284
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.236
SC4MOL	sterol-C4-methyl oxidase-like	0.214
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.151
PEX5	peroxisomal biogenesis factor 5	0.148
DHCR24	24-dehydrocholesterol reductase	0.148
ALB	albumin	0.139
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.129
INSIG1	insulin induced gene 1	0.124
RPL18A	ribosomal protein L18a	0.098
PEX14	peroxisomal biogenesis factor 14	0.092
PYGL	phosphorylase, glycogen, liver	0.078
SREBF2	sterol regulatory element binding transcription factor 2	0.077
CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	0.076
CYP11B2	cytochrome P450, family 11, subfamily B, polypeptide 2	0.066	Human
SQLE	squalene epoxidase	0.061
MVD	mevalonate (diphospho) decarboxylase	0.059
BHMT	betaine--homocysteine S-methyltransferase	0.054
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.053
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.050
NSDHL	NAD(P) dependent steroid dehydrogenase-like	0.048	Human
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.048
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.043
GLYAT	glycine-N-acyltransferase	0.041
PAH	phenylalanine hydroxylase	0.040
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.039	Human
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.036
TM4SF5	transmembrane 4 L six family member 5	0.036
LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.036
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.034
F8	coagulation factor VIII, procoagulant component	0.034
TOM1L1	target of myb1 (chicken)-like 1	0.034
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.033
APOE	apolipoprotein E	0.031
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.029
A2M	alpha-2-macroglobulin	0.028
LHCGR	luteinizing hormone/choriogonadotropin receptor	0.028
MDK	midkine (neurite growth-promoting factor 2)	0.028
RPAIN	RPA interacting protein	0.025
INSR	insulin receptor	0.024
IDI1	isopentenyl-diphosphate delta isomerase 1	0.024
STX12	syntaxin 12	0.022
HPD	4-hydroxyphenylpyruvate dioxygenase	0.022
PDIA3	protein disulfide isomerase family A, member 3	0.021
FADS2	fatty acid desaturase 2	0.021
HP	haptoglobin	0.021
AADAC	arylacetamide deacetylase (esterase)	0.020
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.019
SOCS2	suppressor of cytokine signaling 2	0.019
INHA	inhibin, alpha	0.017
APOB	apolipoprotein B (including Ag(x) antigen)	0.017
MVK	mevalonate kinase	0.017
APOC3	apolipoprotein C-III	0.016
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.016
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.016
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.016
FGB	fibrinogen beta chain	0.016
HSD3B1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.016	Human
CLEC4M	C-type lectin domain family 4, member M	0.015
WDR5B	WD repeat domain 5B	0.015
APOC1	apolipoprotein C-I	0.015
PON1	paraoxonase 1	0.015
LIPC	lipase, hepatic	0.015	Human
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.014
CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	0.014
HAL	histidine ammonia-lyase	0.014
OTC	ornithine carbamoyltransferase	0.014
PRODH2	proline dehydrogenase (oxidase) 2	0.014
LECT2	leukocyte cell-derived chemotaxin 2	0.014
SAA4	serum amyloid A4, constitutive	0.014
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.014
FDPS	farnesyl diphosphate synthase	0.013
GYS2	glycogen synthase 2 (liver)	0.013
DUSP7	dual specificity phosphatase 7	0.013
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.013
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.013	Human
LDLR	low density lipoprotein receptor	0.012
SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	0.012
BARX1	BARX homeobox 1	0.012
TG	thyroglobulin	0.012
ARSE	arylsulfatase E (chondrodysplasia punctata 1)	0.012
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.011
UNC93A	unc-93 homolog A (C. elegans)	0.011
DPYS	dihydropyrimidinase	0.011
TTR	transthyretin	0.011
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.011
DIO1	deiodinase, iodothyronine, type I	0.011
TDO2	tryptophan 2,3-dioxygenase	0.011
EPOR	erythropoietin receptor	0.011
FGA	fibrinogen alpha chain	0.011
PCSK9	proprotein convertase subtilisin/kexin type 9	0.011
G6PC	glucose-6-phosphatase, catalytic subunit	0.011
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.011
AFM	afamin	0.010
MTTP	microsomal triglyceride transfer protein	0.010
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.010
STARD4	StAR-related lipid transfer (START) domain containing 4	0.010
SLC6A4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.010
FABP1	fatty acid binding protein 1, liver	0.010
MAT1A	methionine adenosyltransferase I, alpha	0.010
CDH9	cadherin 9, type 2 (T1-cadherin)	0.010
F11	coagulation factor XI	0.010
ANGPTL3	angiopoietin-like 3	0.010
STAR	steroidogenic acute regulatory protein	0.008
CYP17A1	cytochrome P450, family 17, subfamily A, polypeptide 1	0.007
C7orf16	chromosome 7 open reading frame 16	0.006
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.006
EPHX2	epoxide hydrolase 2, cytoplasmic	0.005
HSD3B2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.005
APOA2	apolipoprotein A-II	0.005
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.005
DHCR7	7-dehydrocholesterol reductase	0.005
GHR	growth hormone receptor	0.005
LCAT	lecithin-cholesterol acyltransferase	0.004
LIPI	lipase, member I	0.004
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.004
CYP11B1	cytochrome P450, family 11, subfamily B, polypeptide 1	0.004
PHYH	phytanoyl-CoA 2-hydroxylase	0.004
LPL	lipoprotein lipase	0.004
HSD3B7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.004
CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2	0.004
AMACR	alpha-methylacyl-CoA racemase	0.004
PEX12	peroxisomal biogenesis factor 12	0.003
APOA5	apolipoprotein A-V	0.003
ECM1	extracellular matrix protein 1	0.003
TAZ	tafazzin	0.003