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Homo sapiens

16 genes annotated in human

chromosomal disease

DOID:0080014

A genetic disease that has material basis in extra, missing, or re-arranged chromosomes.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chromosomal disease"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chromosomal disease" (in gray)

Name	Description	Probability	Func Analog Organism
RORA	RAR-related orphan receptor A	0.855
HIPK2	homeodomain interacting protein kinase 2	0.706
DCAF7	DDB1 and CUL4 associated factor 7	0.623
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.387	Human
EID1	EP300 interacting inhibitor of differentiation 1	0.354
MAP2K4	mitogen-activated protein kinase kinase 4	0.250
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.192	Human
KRTAP4-12	keratin associated protein 4-12	0.107
MAP2K7	mitogen-activated protein kinase kinase 7	0.099
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.066
PHF17	PHD finger protein 17	0.061
GATA4	GATA binding protein 4	0.046	Human
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.046
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.043
TUBB8	tubulin, beta 8	0.039
TAL1	T-cell acute lymphocytic leukemia 1	0.039
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.036
MAPK8	mitogen-activated protein kinase 8	0.035
TBC1D14	TBC1 domain family, member 14	0.030
HDAC4	histone deacetylase 4	0.030
AFTPH	aftiphilin	0.029
PCGF2	polycomb group ring finger 2	0.027
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.024
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.022
GATA2	GATA binding protein 2	0.018	Human
RUNX1	runt-related transcription factor 1	0.018
CASC3	cancer susceptibility candidate 3	0.016
NPAS1	neuronal PAS domain protein 1	0.015
C11orf49	chromosome 11 open reading frame 49	0.015
PRKG2	protein kinase, cGMP-dependent, type II	0.014
NOMO2	NODAL modulator 2	0.014
MDFI	MyoD family inhibitor	0.013
TRIM65	tripartite motif containing 65	0.013
IRS1	insulin receptor substrate 1	0.012
FKBP5	FK506 binding protein 5	0.012
TBX1	T-box 1	0.012
AMHR2	anti-Mullerian hormone receptor, type II	0.011
HSPA1L	heat shock 70kDa protein 1-like	0.011
EID2B	EP300 interacting inhibitor of differentiation 2B	0.011
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.011
ZBTB4	zinc finger and BTB domain containing 4	0.011
SIN3B	SIN3 homolog B, transcription regulator (yeast)	0.011
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.010
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.009
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.008
DHH	desert hedgehog	0.007
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.006
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.005
SNRPN	small nuclear ribonucleoprotein polypeptide N	0.003
NDN	necdin homolog (mouse)	0.003
CDKL5	cyclin-dependent kinase-like 5	0.003
SRY	sex determining region Y	0.002
CBX2	chromobox homolog 2	0.002
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.001
RBM8A	RNA binding motif protein 8A	0.000
UBE3A	ubiquitin protein ligase E3A	0.000