IMP
Process View
interleukin 2 mediated signaling pathway
A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 2 mediated signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 1.000 | Human | |
| GHR | growth hormone receptor | 0.998 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.993 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.967 | ||
| JAK2 | Janus kinase 2 | 0.789 | Human | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.789 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.766 | ||
| EGFR | epidermal growth factor receptor | 0.702 | ||
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.639 | ||
| STAT5B | signal transducer and activator of transcription 5B | 0.542 | ||
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.438 | ||
| IFNGR1 | interferon gamma receptor 1 | 0.411 | ||
| EPOR | erythropoietin receptor | 0.393 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.374 | ||
| ESR1 | estrogen receptor 1 | 0.285 | ||
| LAT | linker for activation of T cells | 0.263 | ||
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.246 | ||
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.235 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.220 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.204 | ||
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.193 | ||
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.144 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.140 | ||
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.134 | ||
| CAPN1 | calpain 1, (mu/I) large subunit | 0.115 | ||
| INSR | insulin receptor | 0.113 | ||
| SH2B1 | SH2B adaptor protein 1 | 0.088 | ||
| DNM2 | dynamin 2 | 0.084 | ||
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.083 | ||
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.044 | ||
| JAK1 | Janus kinase 1 | 0.041 | ||
| IRS1 | insulin receptor substrate 1 | 0.038 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.034 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.034 | ||
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.026 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.026 | ||
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.024 | ||
| BCR | breakpoint cluster region | 0.024 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.023 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.022 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.020 | ||
| SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 0.019 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.018 | ||
| CTTN | cortactin | 0.016 | ||
| NMI | N-myc (and STAT) interactor | 0.016 | ||
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | 0.016 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.012 | ||
| IL6R | interleukin 6 receptor | 0.012 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.012 | ||
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.012 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.011 | ||
| LTK | leukocyte receptor tyrosine kinase | 0.011 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.011 | ||
| IL12RB2 | interleukin 12 receptor, beta 2 | 0.011 | ||
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 | 0.010 | Human | |
| IGF1R | insulin-like growth factor 1 receptor | 0.010 |