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Homo sapiens

2 genes annotated in human

regulation of large conductance calcium activated potassium channel activity

GO:1902606

Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of large conductance calcium activated potassium channel activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of large conductance calcium activated potassium channel activity" (in gray)

Name	Description	Probability	Func Analog Organism
MPDZ	multiple PDZ domain protein	0.998
SSTR3	somatostatin receptor 3	0.892	Human
SSTR2	somatostatin receptor 2	0.758	Human
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.286
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.216
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.153
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.130
GPRASP1	G protein-coupled receptor associated sorting protein 1	0.108
SYN2	synapsin II	0.087
CALY	calcyon neuron-specific vesicular protein	0.076
GRM5	glutamate receptor, metabotropic 5	0.074
PNOC	prepronociceptin	0.069
SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.068
CORT	cortistatin	0.067
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.067
SHANK1	SH3 and multiple ankyrin repeat domains 1	0.066
ADRA1D	adrenergic, alpha-1D-, receptor	0.052
MATN4	matrilin 4	0.045
NOL4	nucleolar protein 4	0.039
SSTR1	somatostatin receptor 1	0.037	Human
GRIK3	glutamate receptor, ionotropic, kainate 3	0.035
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.034
DRD2	dopamine receptor D2	0.033
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	0.033
GPR6	G protein-coupled receptor 6	0.033
GRM1	glutamate receptor, metabotropic 1	0.032
NEURL	neuralized homolog (Drosophila)	0.031
PKDREJ	polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)	0.031
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.030
ZFR2	zinc finger RNA binding protein 2	0.028
VSTM2A	V-set and transmembrane domain containing 2A	0.028
CHGB	chromogranin B (secretogranin 1)	0.028
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.028
GIP	gastric inhibitory polypeptide	0.027
GJA4	gap junction protein, alpha 4, 37kDa	0.027
C15orf2	chromosome 15 open reading frame 2	0.027
HRH3	histamine receptor H3	0.026
GP5	glycoprotein V (platelet)	0.026
ADAM11	ADAM metallopeptidase domain 11	0.024
SST	somatostatin	0.023
CTNNA2	catenin (cadherin-associated protein), alpha 2	0.023
GALR3	galanin receptor 3	0.022	Human
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.022
ENPP7	ectonucleotide pyrophosphatase/phosphodiesterase 7	0.021
ATP4A	ATPase, H+/K+ exchanging, alpha polypeptide	0.020
SYP	synaptophysin	0.020
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.020
CLCN1	chloride channel 1, skeletal muscle	0.020
CALB1	calbindin 1, 28kDa	0.020
GABRD	gamma-aminobutyric acid (GABA) A receptor, delta	0.020
PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	0.019
CACNG2	calcium channel, voltage-dependent, gamma subunit 2	0.019
VGF	VGF nerve growth factor inducible	0.019
CRP	C-reactive protein, pentraxin-related	0.019
GAL	galanin prepropeptide	0.019
CELA2A	chymotrypsin-like elastase family, member 2A	0.019
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.019
POU2F2	POU class 2 homeobox 2	0.019
FOXL2	forkhead box L2	0.019
KCNJ3	potassium inwardly-rectifying channel, subfamily J, member 3	0.019
INA	internexin neuronal intermediate filament protein, alpha	0.018
VAX2	ventral anterior homeobox 2	0.018
KLHL35	kelch-like 35 (Drosophila)	0.018
BARX1	BARX homeobox 1	0.018
LMO1	LIM domain only 1 (rhombotin 1)	0.018
THPO	thrombopoietin	0.018
GPR12	G protein-coupled receptor 12	0.018
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.018
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.017
KCNK13	potassium channel, subfamily K, member 13	0.017
ADCYAP1	adenylate cyclase activating polypeptide 1 (pituitary)	0.017
LYPD4	LY6/PLAUR domain containing 4	0.017
OPRK1	opioid receptor, kappa 1	0.017	Human
UROC1	urocanase domain containing 1	0.017
C1orf68	chromosome 1 open reading frame 68	0.017
CCKBR	cholecystokinin B receptor	0.017
NPPC	natriuretic peptide C	0.017
SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)	0.017
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.017
KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4	0.017
LHB	luteinizing hormone beta polypeptide	0.017
GALR1	galanin receptor 1	0.016	Human
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.016
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.016
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.016
RGS7	regulator of G-protein signaling 7	0.016
SIAH3	seven in absentia homolog 3 (Drosophila)	0.016
B4GALNT1	beta-1,4-N-acetyl-galactosaminyl transferase 1	0.016
MCHR1	melanin-concentrating hormone receptor 1	0.016	Human
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.016
COL19A1	collagen, type XIX, alpha 1	0.016
KCNJ11	potassium inwardly-rectifying channel, subfamily J, member 11	0.016
MTUS2	microtubule associated tumor suppressor candidate 2	0.016
SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.015
GHRHR	growth hormone releasing hormone receptor	0.015
NEUROD2	neurogenic differentiation 2	0.015
SYT3	synaptotagmin III	0.015
MLN	motilin	0.015
ITPKA	inositol-trisphosphate 3-kinase A	0.015
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.015
UTS2R	urotensin 2 receptor	0.015
NKX2-1	NK2 homeobox 1	0.015
NOS1	nitric oxide synthase 1 (neuronal)	0.015
SCG2	secretogranin II	0.015
RHBDL1	rhomboid, veinlet-like 1 (Drosophila)	0.015
NEUROG3	neurogenin 3	0.015
KCNK4	potassium channel, subfamily K, member 4	0.015
PRKCG	protein kinase C, gamma	0.015
NR2E1	nuclear receptor subfamily 2, group E, member 1	0.015
ASGR1	asialoglycoprotein receptor 1	0.014
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.014
SCN2B	sodium channel, voltage-gated, type II, beta	0.014
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.014
NTN3	netrin 3	0.014
CDH8	cadherin 8, type 2	0.014
IL1RL2	interleukin 1 receptor-like 2	0.014
NGB	neuroglobin	0.014
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.014
SYT5	synaptotagmin V	0.014
PAX7	paired box 7	0.014
CITED1	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1	0.014
CLCNKB	chloride channel Kb	0.014
C2orf55	chromosome 2 open reading frame 55	0.013
GNG4	guanine nucleotide binding protein (G protein), gamma 4	0.013
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.013
RLN1	relaxin 1	0.013
CRX	cone-rod homeobox	0.013
MTNR1A	melatonin receptor 1A	0.013
CRHR1	corticotropin releasing hormone receptor 1	0.013
DLL3	delta-like 3 (Drosophila)	0.013
PCSK1	proprotein convertase subtilisin/kexin type 1	0.013
SYN3	synapsin III	0.013
GP2	glycoprotein 2 (zymogen granule membrane)	0.013
RGS6	regulator of G-protein signaling 6	0.013
DRD3	dopamine receptor D3	0.013
S1PR5	sphingosine-1-phosphate receptor 5	0.013
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.013
FAM5C	family with sequence similarity 5, member C	0.013
KREMEN2	kringle containing transmembrane protein 2	0.013
OPCML	opioid binding protein/cell adhesion molecule-like	0.013
BMP8A	bone morphogenetic protein 8a	0.013
TFR2	transferrin receptor 2	0.013
EMX1	empty spiracles homeobox 1	0.013
GPR173	G protein-coupled receptor 173	0.013
GHSR	growth hormone secretagogue receptor	0.012
NEUROD1	neurogenic differentiation 1	0.012
STX1A	syntaxin 1A (brain)	0.012
CAMK1G	calcium/calmodulin-dependent protein kinase IG	0.012
PIWIL1	piwi-like 1 (Drosophila)	0.012
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.012
SIX2	SIX homeobox 2	0.012
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.012
PHOX2B	paired-like homeobox 2b	0.012
TFF3	trefoil factor 3 (intestinal)	0.012
ALK	anaplastic lymphoma receptor tyrosine kinase	0.012
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.012
CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	0.012
SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5	0.012
GRIA1	glutamate receptor, ionotropic, AMPA 1	0.012
DCC	deleted in colorectal carcinoma	0.012
GUCA1A	guanylate cyclase activator 1A (retina)	0.012
NPY5R	neuropeptide Y receptor Y5	0.012
NXPH2	neurexophilin 2	0.012
GUCY2D	guanylate cyclase 2D, membrane (retina-specific)	0.012
GJD2	gap junction protein, delta 2, 36kDa	0.012
TRIM46	tripartite motif containing 46	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
NKX2-8	NK2 homeobox 8	0.012
ARTN	artemin	0.012
GRIK1	glutamate receptor, ionotropic, kainate 1	0.011
KLHL25	kelch-like 25 (Drosophila)	0.011
SLC30A10	solute carrier family 30, member 10	0.011
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.011
CYP2W1	cytochrome P450, family 2, subfamily W, polypeptide 1	0.011
GABRG3	gamma-aminobutyric acid (GABA) A receptor, gamma 3	0.011
F12	coagulation factor XII (Hageman factor)	0.011
SHH	sonic hedgehog	0.011
STAR	steroidogenic acute regulatory protein	0.011
GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)	0.011
HCRTR1	hypocretin (orexin) receptor 1	0.011
NMNAT2	nicotinamide nucleotide adenylyltransferase 2	0.011
GLI4	GLI family zinc finger 4	0.011
ICAM5	intercellular adhesion molecule 5, telencephalin	0.011
CPLX2	complexin 2	0.011
KCNK9	potassium channel, subfamily K, member 9	0.011
CALB2	calbindin 2	0.011
PTH2R	parathyroid hormone 2 receptor	0.011
GRIK4	glutamate receptor, ionotropic, kainate 4	0.011
LDHC	lactate dehydrogenase C	0.011
CCIN	calicin	0.011
NXPH3	neurexophilin 3	0.011
NTSR1	neurotensin receptor 1 (high affinity)	0.011
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.011
POU4F3	POU class 4 homeobox 3	0.011
OGDHL	oxoglutarate dehydrogenase-like	0.011
CHD5	chromodomain helicase DNA binding protein 5	0.011
PITPNM3	PITPNM family member 3	0.011
CRH	corticotropin releasing hormone	0.011
KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4	0.011
HTR6	5-hydroxytryptamine (serotonin) receptor 6	0.011
HNF1A	HNF1 homeobox A	0.011
FGF22	fibroblast growth factor 22	0.011
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.011
PTPRN	protein tyrosine phosphatase, receptor type, N	0.011
TMSB4Y	thymosin beta 4, Y-linked	0.011
KCNV1	potassium channel, subfamily V, member 1	0.010
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.010
TKTL2	transketolase-like 2	0.010
NPTX1	neuronal pentraxin I	0.010
ANKLE1	ankyrin repeat and LEM domain containing 1	0.010
SRRM4	serine/arginine repetitive matrix 4	0.010
OXT	oxytocin, prepropeptide	0.010
LHFPL3	lipoma HMGIC fusion partner-like 3	0.010
SDS	serine dehydratase	0.010
TMEM151B	transmembrane protein 151B	0.010
SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.010
ADAM2	ADAM metallopeptidase domain 2	0.010
KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9	0.010
HSPB9	heat shock protein, alpha-crystallin-related, B9	0.010
HPCA	hippocalcin	0.010
HSD17B1	hydroxysteroid (17-beta) dehydrogenase 1	0.010
GABRA5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.010
SPATC1	spermatogenesis and centriole associated 1	0.010
HOXD11	homeobox D11	0.010
MSTN	myostatin	0.010
RIMS1	regulating synaptic membrane exocytosis 1	0.010
BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)	0.010
GFRA2	GDNF family receptor alpha 2	0.010