IMP
Process View
interleukin 1 biosynthetic process
The chemical reactions and pathways resulting in the formation of interleukin-1, an interleukin produced mainly by activated macrophages. It is involved in the inflammatory response, and is identified as an endogenous pyrogen.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 1 biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| GNLY | granulysin | 0.998 | ||
| NKG7 | natural killer cell group 7 sequence | 0.849 | ||
| PRF1 | perforin 1 (pore forming protein) | 0.775 | ||
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.686 | Human | |
| ELANE | elastase, neutrophil expressed | 0.473 | Human | |
| CTSG | cathepsin G | 0.299 | Human | |
| MPO | myeloperoxidase | 0.227 | ||
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.162 | ||
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.156 | Human | |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.147 | ||
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.124 | ||
| CST7 | cystatin F (leukocystatin) | 0.124 | ||
| IL2RB | interleukin 2 receptor, beta | 0.105 | ||
| CD8A | CD8a molecule | 0.101 | ||
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.098 | Human | |
| CTSW | cathepsin W | 0.087 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.087 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.086 | ||
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.086 | ||
| ITK | IL2-inducible T-cell kinase | 0.081 | ||
| IL18RAP | interleukin 18 receptor accessory protein | 0.062 | ||
| GPR171 | G protein-coupled receptor 171 | 0.056 | ||
| CD2 | CD2 molecule | 0.052 | ||
| RNASE3 | ribonuclease, RNase A family, 3 | 0.051 | ||
| IFNG | interferon, gamma | 0.049 | ||
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.046 | ||
| SH2D1A | SH2 domain containing 1A | 0.045 | ||
| HDC | histidine decarboxylase | 0.042 | ||
| PGLYRP1 | peptidoglycan recognition protein 1 | 0.040 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.039 | ||
| CAMP | cathelicidin antimicrobial peptide | 0.038 | ||
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.036 | ||
| GZMM | granzyme M (lymphocyte met-ase 1) | 0.031 | ||
| DEFA4 | defensin, alpha 4, corticostatin | 0.031 | ||
| TARP | TCR gamma alternate reading frame protein | 0.027 | ||
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.024 | ||
| BPI | bactericidal/permeability-increasing protein | 0.021 | ||
| CPA3 | carboxypeptidase A3 (mast cell) | 0.020 | ||
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.019 | Human | |
| CD96 | CD96 molecule | 0.018 | ||
| GFI1 | growth factor independent 1 transcription repressor | 0.017 | ||
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 0.016 | ||
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.016 | ||
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 | 0.014 | ||
| LTF | lactotransferrin | 0.013 | ||
| CD48 | CD48 molecule | 0.013 | ||
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.012 | ||
| CLC | Charcot-Leyden crystal protein | 0.012 | ||
| CLEC4G | C-type lectin domain family 4, member G | 0.012 | ||
| XCL2 | chemokine (C motif) ligand 2 | 0.012 | ||
| IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 0.012 | ||
| CD160 | CD160 molecule | 0.012 | ||
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | 0.011 | ||
| LTC4S | leukotriene C4 synthase | 0.011 | ||
| ICOS | inducible T-cell co-stimulator | 0.011 | ||
| SRGN | serglycin | 0.011 | ||
| STAT4 | signal transducer and activator of transcription 4 | 0.011 | ||
| RETN | resistin | 0.010 | ||
| CLEC10A | C-type lectin domain family 10, member A | 0.010 |