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Homo sapiens

3 genes annotated in human

adenylate cyclase activating adrenergic receptor signaling pathway

The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "adenylate cyclase activating adrenergic receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "adenylate cyclase activating adrenergic receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.903
ARRB1	arrestin, beta 1	0.903
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.887
MPDZ	multiple PDZ domain protein	0.881
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.851
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.449
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.256
NCF1	neutrophil cytosolic factor 1	0.137
NUCB1	nucleobindin 1	0.128
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.128
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.109
CXCR5	chemokine (C-X-C motif) receptor 5	0.091
NCF2	neutrophil cytosolic factor 2	0.079
ARRDC3	arrestin domain containing 3	0.066
RAP1A	RAP1A, member of RAS oncogene family	0.055
PTEN	phosphatase and tensin homolog	0.053
MAPK10	mitogen-activated protein kinase 10	0.044
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.038
BZW1	basic leucine zipper and W2 domains 1	0.035
NCF4	neutrophil cytosolic factor 4, 40kDa	0.034
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.033
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.031
GNG2	guanine nucleotide binding protein (G protein), gamma 2	0.028
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.027
ARRB2	arrestin, beta 2	0.026
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.026
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.024
RGS19	regulator of G-protein signaling 19	0.022
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.022
GNAS	GNAS complex locus	0.022
PKN2	protein kinase N2	0.021
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.020
GNMT	glycine N-methyltransferase	0.020
CAPNS1	calpain, small subunit 1	0.019
EZR	ezrin	0.018
C14orf176	chromosome 14 open reading frame 176	0.018
ADRBK1	adrenergic, beta, receptor kinase 1	0.018
AGTR1	angiotensin II receptor, type 1	0.018
ATP8	ATP synthase F0 subunit 8	0.018
OR2AG1	olfactory receptor, family 2, subfamily AG, member 1	0.017
BAI1	brain-specific angiogenesis inhibitor 1	0.017
RYBP	RING1 and YY1 binding protein	0.017
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.017
CDV3	CDV3 homolog (mouse)	0.016
CORO1C	coronin, actin binding protein, 1C	0.016
MT1A	metallothionein 1A	0.016
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.015
DCTN2	dynactin 2 (p50)	0.015
ACTN4	actinin, alpha 4	0.015
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.015	Human
SSTR3	somatostatin receptor 3	0.014
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.014	Human
EIF5	eukaryotic translation initiation factor 5	0.014
DSCAML1	Down syndrome cell adhesion molecule like 1	0.014
FASN	fatty acid synthase	0.014
CFL1	cofilin 1 (non-muscle)	0.013
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.013
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.013
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.013
MYH9	myosin, heavy chain 9, non-muscle	0.013
SECISBP2L	SECIS binding protein 2-like	0.013
RGS4	regulator of G-protein signaling 4	0.013
TSHR	thyroid stimulating hormone receptor	0.012
DNM1	dynamin 1	0.012
GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.012
GPR6	G protein-coupled receptor 6	0.012
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.012
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.012
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.012
LPHN3	latrophilin 3	0.012
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.012	Human
RAP1B	RAP1B, member of RAS oncogene family	0.012
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.012
RGS5	regulator of G-protein signaling 5	0.012
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.011
DRD1	dopamine receptor D1	0.011	Human
NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	0.011
ARHGAP29	Rho GTPase activating protein 29	0.011
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.011
OPRM1	opioid receptor, mu 1	0.011
YAP1	Yes-associated protein 1	0.011
RGS14	regulator of G-protein signaling 14	0.011
DPP6	dipeptidyl-peptidase 6	0.011
ADRB2	adrenergic, beta-2-, receptor, surface	0.011	Human
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.011
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.011
NT5C3	5'-nucleotidase, cytosolic III	0.011
OXSR1	oxidative-stress responsive 1	0.011
FEZF2	FEZ family zinc finger 2	0.011
AES	amino-terminal enhancer of split	0.011
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.011
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D	0.011	Human
YY1	YY1 transcription factor	0.010
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.010
CADM3	cell adhesion molecule 3	0.010
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.010
GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.010
COPG2	coatomer protein complex, subunit gamma 2	0.010
MED28	mediator complex subunit 28	0.010
CDH8	cadherin 8, type 2	0.010
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.010
RELN	reelin	0.010
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.010
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A	0.010	Human
TBC1D10A	TBC1 domain family, member 10A	0.010
PTPRA	protein tyrosine phosphatase, receptor type, A	0.010
OPCML	opioid binding protein/cell adhesion molecule-like	0.010
GPSM2	G-protein signaling modulator 2	0.010