IMP

Process View

Homo sapiens

24 genes annotated in human

Multi-species View

regulation of actin filament based movement

GO:1903115

Any process that modulates the frequency, rate or extent of actin filament-based movement.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of actin filament based movement"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of actin filament based movement" (in gray)

Name	Description	Probability	Func Analog Organism
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.976	Human
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.952
MPZL2	myelin protein zero-like 2	0.902	Human
DSP	desmoplakin	0.891
JUP	junction plakoglobin	0.870
DLG4	discs, large homolog 4 (Drosophila)	0.859
DSC2	desmocollin 2	0.852
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.835
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.831
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.817	Human
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.758
DSG2	desmoglein 2	0.711
MPZL3	myelin protein zero-like 3	0.711	Human
ACTN2	actinin, alpha 2	0.691
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.662
SFN	stratifin	0.662
KCNIP2	Kv channel interacting protein 2	0.641
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.640
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.576
SNTG2	syntrophin, gamma 2	0.538	Human
MAPK12	mitogen-activated protein kinase 12	0.529
LIN7B	lin-7 homolog B (C. elegans)	0.500
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.460
TNNI1	troponin I type 1 (skeletal, slow)	0.434
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.402
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.402	Human
DMD	dystrophin	0.381
KRT14	keratin 14	0.251
SPTB	spectrin, beta, erythrocytic	0.247
PSEN1	presenilin 1	0.229
KCNA1	potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)	0.219	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.212	Human
ESR2	estrogen receptor 2 (ER beta)	0.206
PKP3	plakophilin 3	0.202	Human
APC	adenomatous polyposis coli	0.198
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.189	Human
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.142
CLCN3	chloride channel 3	0.129
ERBB2IP	erbb2 interacting protein	0.120
LAD1	ladinin 1	0.102
DTNA	dystrobrevin, alpha	0.097
TRIM29	tripartite motif containing 29	0.093
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.091
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.075
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.071	Human
CTNNBIP1	catenin, beta interacting protein 1	0.066
ADAM11	ADAM metallopeptidase domain 11	0.066
PDCD6	programmed cell death 6	0.059
GRIN2C	glutamate receptor, ionotropic, N-methyl D-aspartate 2C	0.054
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.053
GJB3	gap junction protein, beta 3, 31kDa	0.052	Human
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.050	Human
DSC3	desmocollin 3	0.049	Human
TNNT2	troponin T type 2 (cardiac)	0.049	Rat
AKAP6	A kinase (PRKA) anchor protein 6	0.044
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.043
KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1	0.042
GLE1	GLE1 RNA export mediator homolog (yeast)	0.041
FRMD5	FERM domain containing 5	0.039
KCNIP1	Kv channel interacting protein 1	0.036
TBX5	T-box 5	0.036
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.036
TNNC1	troponin C type 1 (slow)	0.036	Mouse
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.036
PKP2	plakophilin 2	0.036
RHAG	Rh-associated glycoprotein	0.035
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.035
DSG1	desmoglein 1	0.035	Human
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.035
ZFYVE9	zinc finger, FYVE domain containing 9	0.033
KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2	0.032	Human
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.032
BAI1	brain-specific angiogenesis inhibitor 1	0.032
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.031	Human
FRS2	fibroblast growth factor receptor substrate 2	0.030
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.029
DLGAP1	discs, large (Drosophila) homolog-associated protein 1	0.028
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	0.028	Human
EHD1	EH-domain containing 1	0.028
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	0.027
BTRC	beta-transducin repeat containing	0.027
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.026	Human
GJB5	gap junction protein, beta 5, 31.1kDa	0.026	Human
UTRN	utrophin	0.026
KCNH1	potassium voltage-gated channel, subfamily H (eag-related), member 1	0.026	Human
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.025
KCNB2	potassium voltage-gated channel, Shab-related subfamily, member 2	0.024	Human
MYOZ1	myozenin 1	0.023
PDZK1	PDZ domain containing 1	0.023
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.022
KRT6B	keratin 6B	0.022
DSG3	desmoglein 3	0.022	Human
IRF6	interferon regulatory factor 6	0.021
COL17A1	collagen, type XVII, alpha 1	0.021
TNNI3	troponin I type 3 (cardiac)	0.021
PECAM1	platelet/endothelial cell adhesion molecule	0.021
ITGB4	integrin, beta 4	0.020
DPP6	dipeptidyl-peptidase 6	0.020
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.020
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.020
CAPN2	calpain 2, (m/II) large subunit	0.019
BSN	bassoon (presynaptic cytomatrix protein)	0.019
LRRC7	leucine rich repeat containing 7	0.019
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.019
HRH3	histamine receptor H3	0.018
PERP	PERP, TP53 apoptosis effector	0.018
OSBP2	oxysterol binding protein 2	0.017
OPRD1	opioid receptor, delta 1	0.017
KRT8	keratin 8	0.016
MARK3	MAP/microtubule affinity-regulating kinase 3	0.016
ADRA1D	adrenergic, alpha-1D-, receptor	0.016
SCEL	sciellin	0.016
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.015
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.015
SEZ6L	seizure related 6 homolog (mouse)-like	0.015
TGFA	transforming growth factor, alpha	0.015
FXYD3	FXYD domain containing ion transport regulator 3	0.015
TGFBR1	transforming growth factor, beta receptor 1	0.015
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.014
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.014
LDB3	LIM domain binding 3	0.014
SOX15	SRY (sex determining region Y)-box 15	0.014
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.014
KCNG4	potassium voltage-gated channel, subfamily G, member 4	0.014	Human
DDN	dendrin	0.014
KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.014	Human
LYPD3	LY6/PLAUR domain containing 3	0.014
SCN2B	sodium channel, voltage-gated, type II, beta	0.014
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.013
PSEN2	presenilin 2 (Alzheimer disease 4)	0.013
KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2	0.013	Human
KRT18	keratin 18	0.013
PGAM2	phosphoglycerate mutase 2 (muscle)	0.013
TNNI2	troponin I type 2 (skeletal, fast)	0.013
HAND2	heart and neural crest derivatives expressed 2	0.013
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.013
KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.013	Human
SCN3B	sodium channel, voltage-gated, type III, beta	0.013
CALCOCO2	calcium binding and coiled-coil domain 2	0.013
TNNC2	troponin C type 2 (fast)	0.013
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.013	Human
KLK10	kallikrein-related peptidase 10	0.013
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.013
FGFBP1	fibroblast growth factor binding protein 1	0.012
KCNH6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.012	Human
TACSTD2	tumor-associated calcium signal transducer 2	0.012
KRT5	keratin 5	0.012
NLGN1	neuroligin 1	0.012
CCKBR	cholecystokinin B receptor	0.012
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.012	Human
TLL2	tolloid-like 2	0.012
LAMC2	laminin, gamma 2	0.012
RANBP9	RAN binding protein 9	0.012
S100A14	S100 calcium binding protein A14	0.012
SLC12A5	solute carrier family 12 (potassium/chloride transporter), member 5	0.012
WSCD2	WSC domain containing 2	0.012
SPRR1B	small proline-rich protein 1B	0.012
TBR1	T-box, brain, 1	0.012
SMAD2	SMAD family member 2	0.011
CAV3	caveolin 3	0.011
SLC4A3	solute carrier family 4, anion exchanger, member 3	0.011
GLIS2	GLIS family zinc finger 2	0.011
KCNG3	potassium voltage-gated channel, subfamily G, member 3	0.011	Human
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.011
IVL	involucrin	0.011
CDH22	cadherin 22, type 2	0.011
PKP4	plakophilin 4	0.011	Human
ADRB1	adrenergic, beta-1-, receptor	0.011	Rat
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.011
CRYBB1	crystallin, beta B1	0.011
NOS1	nitric oxide synthase 1 (neuronal)	0.011
CDH5	cadherin 5, type 2 (vascular endothelium)	0.011
FOXN1	forkhead box N1	0.011
GRM7	glutamate receptor, metabotropic 7	0.011
SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.011
KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6	0.011	Human
VGLL1	vestigial like 1 (Drosophila)	0.011
SYN2	synapsin II	0.010
SFRP5	secreted frizzled-related protein 5	0.010
KRT16	keratin 16	0.010
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.010
DLG2	discs, large homolog 2 (Drosophila)	0.010
CRB3	crumbs homolog 3 (Drosophila)	0.010
DES	desmin	0.010
CACNA1B	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.010
CLDN4	claudin 4	0.010
SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.010
CPLX2	complexin 2	0.010
TTR	transthyretin	0.010