IMP

Process View

Homo sapiens

12 genes annotated in human

positive regulation of glucose metabolic process

Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of glucose metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of glucose metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	0.998
IRS1	insulin receptor substrate 1	0.920
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.865
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.865
IGF1R	insulin-like growth factor 1 receptor	0.798	Human
GRB10	growth factor receptor-bound protein 10	0.767
GHR	growth hormone receptor	0.675
IRS2	insulin receptor substrate 2	0.528
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.471	Human
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.410
CREBBP	CREB binding protein	0.403
NCOA1	nuclear receptor coactivator 1	0.350
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.289
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.272
AR	androgen receptor	0.243
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.236	Yeast
PRKCZ	protein kinase C, zeta	0.187	Human
TRRAP	transformation/transcription domain-associated protein	0.151
FYN	FYN oncogene related to SRC, FGR, YES	0.132
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.132
HIPK2	homeodomain interacting protein kinase 2	0.116
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.112
NOXA1	NADPH oxidase activator 1	0.107
DCAF7	DDB1 and CUL4 associated factor 7	0.094
EP300	E1A binding protein p300	0.083
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.082	Yeast
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.080
EGFR	epidermal growth factor receptor	0.068
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.068
LZTS2	leucine zipper, putative tumor suppressor 2	0.068
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.065
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.060
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.057
ITGB1BP3	integrin beta 1 binding protein 3	0.055
NCOA6	nuclear receptor coactivator 6	0.052
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.047	Yeast
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.043	Human
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.042
FOXO3	forkhead box O3	0.041
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.039
UBQLN1	ubiquilin 1	0.036
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.036
SREBF2	sterol regulatory element binding transcription factor 2	0.032
SIRT1	sirtuin 1	0.032
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.030
PSEN1	presenilin 1	0.030
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.029
PROX1	prospero homeobox 1	0.029
SH2B1	SH2B adaptor protein 1	0.027
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.027
PICK1	protein interacting with PRKCA 1	0.026
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.026	Human
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.025
FHL2	four and a half LIM domains 2	0.023
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.023
IGF2R	insulin-like growth factor 2 receptor	0.022
NCOR2	nuclear receptor corepressor 2	0.021
USP22	ubiquitin specific peptidase 22	0.021
ACACA	acetyl-CoA carboxylase alpha	0.020
CHD9	chromodomain helicase DNA binding protein 9	0.020
CDCP1	CUB domain containing protein 1	0.020
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.019
TADA2A	transcriptional adaptor 2A	0.019
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.018
CD33	CD33 molecule	0.018
HNF1A	HNF1 homeobox A	0.018
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.017
GSK3B	glycogen synthase kinase 3 beta	0.017
STAT5B	signal transducer and activator of transcription 5B	0.017
ARIH2	ariadne homolog 2 (Drosophila)	0.017
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.016
LAT	linker for activation of T cells	0.016
NUMB	numb homolog (Drosophila)	0.015
NCOA2	nuclear receptor coactivator 2	0.015
VHL	von Hippel-Lindau tumor suppressor	0.015
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.013
EPOR	erythropoietin receptor	0.013
FGFR1	fibroblast growth factor receptor 1	0.013
MORF4L1	mortality factor 4 like 1	0.013
PPARG	peroxisome proliferator-activated receptor gamma	0.012
CARD11	caspase recruitment domain family, member 11	0.012
RUNX1	runt-related transcription factor 1	0.012
HIC1	hypermethylated in cancer 1	0.012
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.012
CUX1	cut-like homeobox 1	0.011
ESRRG	estrogen-related receptor gamma	0.011
JAK2	Janus kinase 2	0.011
CCDC101	coiled-coil domain containing 101	0.011
FOXO1	forkhead box O1	0.011	Mouse
KAT2B	K(lysine) acetyltransferase 2B	0.011	Mouse
E2F2	E2F transcription factor 2	0.011
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.010