IMP
Process View
pro b cell differentiation
The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "pro b cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| APLF | aprataxin and PNKP like factor | 0.999 | ||
| LIG4 | ligase IV, DNA, ATP-dependent | 0.983 | Mouse | |
| JAG1 | jagged 1 | 0.646 | ||
| APTX | aprataxin | 0.458 | ||
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.272 | ||
| ITSN2 | intersectin 2 | 0.269 | ||
| PNKP | polynucleotide kinase 3'-phosphatase | 0.257 | ||
| NOTCH3 | notch 3 | 0.256 | ||
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 0.226 | Mouse | |
| LAT | linker for activation of T cells | 0.213 | ||
| NHEJ1 | nonhomologous end-joining factor 1 | 0.205 | ||
| MAML1 | mastermind-like 1 (Drosophila) | 0.188 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.130 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.105 | Mouse | |
| PLCG1 | phospholipase C, gamma 1 | 0.098 | ||
| ABI1 | abl-interactor 1 | 0.061 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.041 | ||
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.040 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.034 | ||
| DNM1 | dynamin 1 | 0.029 | ||
| CSNK1E | casein kinase 1, epsilon | 0.026 | ||
| WASL | Wiskott-Aldrich syndrome-like | 0.026 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.023 | ||
| MARCKSL1 | MARCKS-like 1 | 0.023 | ||
| SH3PXD2A | SH3 and PX domains 2A | 0.022 | ||
| NCK1 | NCK adaptor protein 1 | 0.019 | ||
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.018 | ||
| JAG2 | jagged 2 | 0.016 | ||
| DLL1 | delta-like 1 (Drosophila) | 0.016 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.016 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.015 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.015 | ||
| SOS2 | son of sevenless homolog 2 (Drosophila) | 0.015 | Mouse | |
| NOTCH2 | notch 2 | 0.015 | ||
| ZNF331 | zinc finger protein 331 | 0.015 | ||
| RHOU | ras homolog gene family, member U | 0.014 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.014 | ||
| GFI1B | growth factor independent 1B transcription repressor | 0.014 | ||
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.013 | ||
| ESPN | espin | 0.013 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.012 | ||
| OCLN | occludin | 0.012 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.012 | ||
| PIK3AP1 | phosphoinositide-3-kinase adaptor protein 1 | 0.012 | ||
| RGS3 | regulator of G-protein signaling 3 | 0.011 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.011 | ||
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | 0.011 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.011 | ||
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.010 |