IMP
Process View
trigeminal nerve morphogenesis
The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "trigeminal nerve morphogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.998 | Mouse | |
| Arhgef11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.992 | ||
| Nrp2 | neuropilin 2 | 0.917 | ||
| Ednra | endothelin receptor type A | 0.885 | ||
| Plxna1 | plexin A1 | 0.818 | Mouse | |
| Epha4 | Eph receptor A4 | 0.553 | ||
| Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.382 | Mouse | |
| Plxna4 | plexin A4 | 0.376 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.343 | ||
| Arhgef12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.279 | ||
| Grb10 | growth factor receptor bound protein 10 | 0.191 | ||
| Sema3f | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F | 0.161 | ||
| Fscn1 | fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) | 0.141 | ||
| Sdc3 | syndecan 3 | 0.104 | ||
| Mmp15 | matrix metallopeptidase 15 | 0.083 | ||
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.070 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.061 | ||
| Ece1 | endothelin converting enzyme 1 | 0.054 | ||
| Ids | iduronate 2-sulfatase | 0.052 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.050 | ||
| Sema3c | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.046 | Mouse | |
| Cdk14 | cyclin-dependent kinase 14 | 0.046 | ||
| Itga3 | integrin alpha 3 | 0.046 | ||
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.045 | ||
| Sema3a | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.041 | ||
| Kdr | kinase insert domain protein receptor | 0.040 | ||
| Plcg1 | phospholipase C, gamma 1 | 0.040 | ||
| Mid2 | midline 2 | 0.040 | ||
| Vegfa | vascular endothelial growth factor A | 0.039 | ||
| Nrcam | neuron-glia-CAM-related cell adhesion molecule | 0.039 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.038 | ||
| Emp2 | epithelial membrane protein 2 | 0.036 | ||
| Tspan9 | tetraspanin 9 | 0.035 | ||
| Rgnef | Rho-guanine nucleotide exchange factor | 0.032 | ||
| Tcf4 | transcription factor 4 | 0.031 | ||
| Clip2 | CAP-GLY domain containing linker protein 2 | 0.026 | ||
| Id1 | inhibitor of DNA binding 1 | 0.025 | ||
| Plxna2 | plexin A2 | 0.023 | Mouse | |
| Nynrin | NYN domain and retroviral integrase containing | 0.022 | ||
| Bcar1 | breast cancer anti-estrogen resistance 1 | 0.022 | ||
| Ptpru | protein tyrosine phosphatase, receptor type, U | 0.021 | ||
| Nes | nestin | 0.021 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.021 | ||
| Mgat3 | mannoside acetylglucosaminyltransferase 3 | 0.020 | ||
| Sh3rf1 | SH3 domain containing ring finger 1 | 0.020 | ||
| Dock4 | dedicator of cytokinesis 4 | 0.019 | ||
| Btbd3 | BTB (POZ) domain containing 3 | 0.018 | ||
| Fjx1 | four jointed box 1 (Drosophila) | 0.018 | ||
| Pcdh12 | protocadherin 12 | 0.017 | ||
| Ednrb | endothelin receptor type B | 0.016 | ||
| Dtna | dystrobrevin alpha | 0.016 | ||
| Fat4 | FAT tumor suppressor homolog 4 (Drosophila) | 0.016 | ||
| Agrn | agrin | 0.015 | ||
| Fndc1 | fibronectin type III domain containing 1 | 0.015 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.015 | ||
| Epn2 | epsin 2 | 0.015 | ||
| Klf12 | Kruppel-like factor 12 | 0.014 | ||
| Ptprs | protein tyrosine phosphatase, receptor type, S | 0.014 | ||
| Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.014 | ||
| Plcb1 | phospholipase C, beta 1 | 0.013 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.013 | ||
| Tnks1bp1 | tankyrase 1 binding protein 1 | 0.013 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.013 | ||
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.013 | ||
| Magi1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 | 0.013 | ||
| Ptprk | protein tyrosine phosphatase, receptor type, K | 0.012 | ||
| Itm2c | integral membrane protein 2C | 0.012 | ||
| Maf | avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog | 0.012 | ||
| Ptprg | protein tyrosine phosphatase, receptor type, G | 0.012 | ||
| Dpysl2 | dihydropyrimidinase-like 2 | 0.012 | ||
| Foxp2 | forkhead box P2 | 0.011 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.011 | ||
| Cdh13 | cadherin 13 | 0.011 | ||
| Mrc2 | mannose receptor, C type 2 | 0.011 | ||
| Gpr56 | G protein-coupled receptor 56 | 0.011 | ||
| Cxadr | coxsackie virus and adenovirus receptor | 0.011 | ||
| Arhgef25 | Rho guanine nucleotide exchange factor (GEF) 25 | 0.011 | ||
| Rbfox2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.011 | ||
| Pcdh18 | protocadherin 18 | 0.010 | ||
| Hip1 | huntingtin interacting protein 1 | 0.010 |