IMP
Process View
ionotropic glutamate receptor signaling pathway
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "ionotropic glutamate receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 1.000 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 1.000 | Rat | |
| Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 1.000 | ||
| Gria2 | glutamate receptor, ionotropic, AMPA2 (alpha 2) | 1.000 | ||
| Prnp | prion protein | 0.991 | ||
| App | amyloid beta (A4) precursor protein | 0.962 | ||
| Gria1 | glutamate receptor, ionotropic, AMPA1 (alpha 1) | 0.943 | Human Mouse Worm | |
| Grik2 | glutamate receptor, ionotropic, kainate 2 (beta 2) | 0.830 | ||
| Clstn1 | calsyntenin 1 | 0.714 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.535 | ||
| Dnm1 | dynamin 1 | 0.436 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.414 | ||
| Arc | activity regulated cytoskeletal-associated protein | 0.344 | ||
| Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | 0.342 | ||
| Dlg2 | discs, large homolog 2 (Drosophila) | 0.254 | ||
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.144 | ||
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.115 | Mouse | |
| Cit | citron | 0.113 | ||
| Atp1b1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.084 | ||
| Psen1 | presenilin 1 | 0.076 | ||
| Kifc2 | kinesin family member C2 | 0.061 | ||
| Asap1 | ArfGAP with SH# domain, ankyrin repeat and PH domain1 | 0.058 | ||
| Apbb1 | amyloid beta (A4) precursor protein-binding, family B, member 1 | 0.058 | ||
| Kcnma1 | potassium large conductance calcium-activated channel, subfamily M, alpha member 1 | 0.058 | ||
| Cacng2 | calcium channel, voltage-dependent, gamma subunit 2 | 0.057 | Mouse | |
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.054 | ||
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.054 | ||
| Bsn | bassoon | 0.053 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.050 | ||
| Inadl | InaD-like (Drosophila) | 0.048 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.046 | ||
| Sparcl1 | SPARC-like 1 | 0.044 | ||
| Grin2c | glutamate receptor, ionotropic, NMDA2C (epsilon 3) | 0.041 | ||
| Camk2b | calcium/calmodulin-dependent protein kinase II, beta | 0.040 | ||
| Cntn1 | contactin 1 | 0.040 | ||
| Snap25 | synaptosomal-associated protein 25 | 0.038 | ||
| Odz2 | odd Oz/ten-m homolog 2 (Drosophila) | 0.036 | ||
| Psap | prosaposin | 0.035 | ||
| Vamp2 | vesicle-associated membrane protein 2 | 0.034 | ||
| Aplp2 | amyloid beta (A4) precursor-like protein 2 | 0.031 | Mouse | |
| L1cam | L1 cell adhesion molecule | 0.030 | ||
| Sh3gl2 | SH3-domain GRB2-like 2 | 0.030 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.028 | ||
| Grip1 | glutamate receptor interacting protein 1 | 0.027 | ||
| Tmem146 | transmembrane protein 146 | 0.025 | ||
| Cckbr | cholecystokinin B receptor | 0.025 | ||
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.025 | ||
| Arhgef12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.024 | ||
| Trim46 | tripartite motif-containing 46 | 0.024 | ||
| Hpca | hippocalcin | 0.024 | ||
| Plp1 | proteolipid protein (myelin) 1 | 0.023 | ||
| Prkcb | protein kinase C, beta | 0.023 | ||
| Kalrn | kalirin, RhoGEF kinase | 0.022 | ||
| Slc8a2 | solute carrier family 8 (sodium/calcium exchanger), member 2 | 0.022 | ||
| Nlgn2 | neuroligin 2 | 0.022 | ||
| Pcsk4 | proprotein convertase subtilisin/kexin type 4 | 0.021 | ||
| Mapk3 | mitogen-activated protein kinase 3 | 0.021 | ||
| Itm2b | integral membrane protein 2B | 0.021 | ||
| Nrcam | neuron-glia-CAM-related cell adhesion molecule | 0.021 | ||
| Dlg3 | discs, large homolog 3 (Drosophila) | 0.019 | ||
| Gabbr1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.019 | ||
| Plcb1 | phospholipase C, beta 1 | 0.019 | ||
| Shank2 | SH3/ankyrin domain gene 2 | 0.018 | Mouse | |
| Il16 | interleukin 16 | 0.018 | ||
| Numb | numb gene homolog (Drosophila) | 0.018 | ||
| Sema4g | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G | 0.017 | ||
| Dsg1a | desmoglein 1 alpha | 0.017 | ||
| Syn2 | synapsin II | 0.017 | ||
| Syp | synaptophysin | 0.017 | ||
| Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.017 | ||
| Nynrin | NYN domain and retroviral integrase containing | 0.017 | ||
| Numbl | numb-like | 0.017 | ||
| Adam23 | a disintegrin and metallopeptidase domain 23 | 0.017 | ||
| Nhedc2 | Na+/H+ exchanger domain containing 2 | 0.017 | ||
| Cpd | carboxypeptidase D | 0.017 | ||
| Slc22a17 | solute carrier family 22 (organic cation transporter), member 17 | 0.016 | ||
| Kcnab2 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 0.016 | ||
| Grik4 | glutamate receptor, ionotropic, kainate 4 | 0.016 | Mouse | |
| Slc12a5 | solute carrier family 12, member 5 | 0.016 | ||
| Kcne2 | potassium voltage-gated channel, Isk-related subfamily, gene 2 | 0.015 | ||
| Mtap2 | microtubule-associated protein 2 | 0.015 | ||
| Gria3 | glutamate receptor, ionotropic, AMPA3 (alpha 3) | 0.015 | Human Mouse Rat Worm | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.015 | ||
| Pvrl1 | poliovirus receptor-related 1 | 0.015 | ||
| Aplp1 | amyloid beta (A4) precursor-like protein 1 | 0.014 | Mouse | |
| Prkce | protein kinase C, epsilon | 0.014 | ||
| Exoc4 | exocyst complex component 4 | 0.014 | ||
| Sstr4 | somatostatin receptor 4 | 0.014 | ||
| Nkx6-3 | NK6 homeobox 3 | 0.014 | ||
| Atp1b2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 0.014 | ||
| Cdh8 | cadherin 8 | 0.013 | ||
| Nefl | neurofilament, light polypeptide | 0.013 | ||
| Doc2b | double C2, beta | 0.013 | ||
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.013 | Rat | |
| Tnfrsf8 | tumor necrosis factor receptor superfamily, member 8 | 0.012 | ||
| Kif1a | kinesin family member 1A | 0.012 | ||
| Adam22 | a disintegrin and metallopeptidase domain 22 | 0.012 | ||
| Src | Rous sarcoma oncogene | 0.012 | ||
| Hs6st3 | heparan sulfate 6-O-sulfotransferase 3 | 0.011 | ||
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.011 | ||
| Ptms | parathymosin | 0.011 | ||
| Slc1a3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 0.011 | ||
| Ubxn11 | UBX domain protein 11 | 0.011 | ||
| Cacna1g | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.011 | ||
| Klf1 | Kruppel-like factor 1 (erythroid) | 0.011 | ||
| Rps6ka3 | ribosomal protein S6 kinase polypeptide 3 | 0.011 | ||
| Plcg1 | phospholipase C, gamma 1 | 0.010 | ||
| Cux2 | cut-like homeobox 2 | 0.010 | ||
| Ncam1 | neural cell adhesion molecule 1 | 0.010 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.010 | ||
| Sh3glb2 | SH3-domain GRB2-like endophilin B2 | 0.010 |