IMP
Process View
low density lipoprotein particle clearance
The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "low density lipoprotein particle clearance"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Apoe | apolipoprotein E | 0.908 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.836 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.539 | ||
| Npc1 | Niemann Pick type C1 | 0.371 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.350 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.268 | ||
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.208 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.199 | ||
| Mapk8ip2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.167 | ||
| Tbx3 | T-box 3 | 0.149 | ||
| Apoa1 | apolipoprotein A-I | 0.148 | ||
| Cav1 | caveolin 1, caveolae protein | 0.133 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.111 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.107 | Mouse | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.102 | ||
| Lrp8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.087 | Mouse | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.087 | ||
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.081 | ||
| Ldlr | low density lipoprotein receptor | 0.072 | ||
| Axin1 | axin 1 | 0.071 | ||
| Vegfa | vascular endothelial growth factor A | 0.068 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.064 | ||
| Nphs2 | nephrosis 2 homolog, podocin (human) | 0.059 | ||
| Crtc3 | CREB regulated transcription coactivator 3 | 0.044 | ||
| Klf15 | Kruppel-like factor 15 | 0.040 | ||
| Sertad2 | SERTA domain containing 2 | 0.039 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.037 | ||
| Lpin1 | lipin 1 | 0.036 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.033 | ||
| App | amyloid beta (A4) precursor protein | 0.031 | ||
| Vldlr | very low density lipoprotein receptor | 0.028 | Mouse | |
| Hnrnph2 | heterogeneous nuclear ribonucleoprotein H2 | 0.027 | ||
| Reln | reelin | 0.024 | ||
| Kcnj10 | potassium inwardly-rectifying channel, subfamily J, member 10 | 0.022 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.022 | ||
| Lcat | lecithin cholesterol acyltransferase | 0.022 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.021 | ||
| Ehd4 | EH-domain containing 4 | 0.021 | Mouse | |
| Vkorc1 | vitamin K epoxide reductase complex, subunit 1 | 0.021 | ||
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.021 | Mouse | |
| Pick1 | protein interacting with C kinase 1 | 0.020 | ||
| Sqle | squalene epoxidase | 0.020 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.019 | ||
| Hsd11b1 | hydroxysteroid 11-beta dehydrogenase 1 | 0.019 | ||
| Osbpl8 | oxysterol binding protein-like 8 | 0.018 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.018 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.018 | ||
| Mesdc2 | mesoderm development candidate 2 | 0.018 | ||
| Lpl | lipoprotein lipase | 0.017 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.017 | ||
| Lss | lanosterol synthase | 0.017 | ||
| Pofut1 | protein O-fucosyltransferase 1 | 0.017 | ||
| Ddx5 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | 0.017 | ||
| Psen1 | presenilin 1 | 0.016 | ||
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.016 | ||
| Myo1c | myosin IC | 0.015 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.015 | ||
| Ltbr | lymphotoxin B receptor | 0.015 | ||
| Cdh5 | cadherin 5 | 0.015 | ||
| Sc4mol | sterol-C4-methyl oxidase-like | 0.015 | ||
| Hmgcs1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 0.015 | ||
| Gjb2 | gap junction protein, beta 2 | 0.015 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.014 | ||
| Foxa2 | forkhead box A2 | 0.014 | ||
| Cbx3 | chromobox homolog 3 (Drosophila HP1 gamma) | 0.014 | ||
| Fabp4 | fatty acid binding protein 4, adipocyte | 0.014 | ||
| Agtr2 | angiotensin II receptor, type 2 | 0.014 | ||
| Foxa3 | forkhead box A3 | 0.013 | ||
| Dhcr24 | 24-dehydrocholesterol reductase | 0.013 | ||
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.013 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.013 | ||
| Srsf3 | serine/arginine-rich splicing factor 3 | 0.012 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.012 | ||
| Cyp51 | cytochrome P450, family 51 | 0.012 | ||
| Sox11 | SRY-box containing gene 11 | 0.012 | ||
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.012 | ||
| Igfbp4 | insulin-like growth factor binding protein 4 | 0.012 | ||
| Efemp2 | epidermal growth factor-containing fibulin-like extracellular matrix protein 2 | 0.012 | ||
| Hnf4a | hepatic nuclear factor 4, alpha | 0.012 | ||
| H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) | 0.011 | ||
| Ehd3 | EH-domain containing 3 | 0.011 | Mouse | |
| Txnip | thioredoxin interacting protein | 0.011 | ||
| Hnrnpd | heterogeneous nuclear ribonucleoprotein D | 0.011 | ||
| Dok1 | docking protein 1 | 0.011 | ||
| Myl12b | myosin, light chain 12B, regulatory | 0.011 | ||
| Egfr | epidermal growth factor receptor | 0.010 | ||
| Fn1 | fibronectin 1 | 0.010 |