Process View
The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative to initiate a change in cell activity.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "purinergic receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Mefv | Mediterranean fever | 0.413 | ||
| Slc6a4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.200 | ||
| Trem3 | triggering receptor expressed on myeloid cells 3 | 0.187 | ||
| Chl1 | cell adhesion molecule with homology to L1CAM | 0.169 | ||
| Mb | myoglobin | 0.123 | ||
| Clec7a | C-type lectin domain family 7, member a | 0.075 | ||
| Slc11a1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.073 | ||
| P2ry12 | purinergic receptor P2Y, G-protein coupled 12 | 0.072 | ||
| Emr1 | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 0.071 | ||
| Tifab | TRAF-interacting protein with forkhead-associated domain, family member B | 0.069 | ||
| Pilra | paired immunoglobin-like type 2 receptor alpha | 0.058 | ||
| Cd300a | CD300A antigen | 0.056 | Mouse | |
| Fcgr3 | Fc receptor, IgG, low affinity III | 0.055 | ||
| Trpv1 | transient receptor potential cation channel, subfamily V, member 1 | 0.054 | ||
| C130050O18Rik | RIKEN cDNA C130050O18 gene | 0.053 | ||
| Vip | vasoactive intestinal polypeptide | 0.052 | ||
| Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.048 | ||
| Lair1 | leukocyte-associated Ig-like receptor 1 | 0.048 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.046 | ||
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.045 | ||
| Aatk | apoptosis-associated tyrosine kinase | 0.044 | ||
| Tcfec | transcription factor EC | 0.041 | ||
| B430306N03Rik | RIKEN cDNA B430306N03 gene | 0.041 | ||
| Tbxas1 | thromboxane A synthase 1, platelet | 0.040 | ||
| Cd33 | CD33 antigen | 0.040 | ||
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.040 | ||
| Hcst | hematopoietic cell signal transducer | 0.040 | ||
| P2rx2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.039 | Mouse | |
| Itgax | integrin alpha X | 0.038 | ||
| Clec4n | C-type lectin domain family 4, member n | 0.038 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.037 | ||
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.035 | ||
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.033 | ||
| Ptgir | prostaglandin I receptor (IP) | 0.033 | ||
| Gpr84 | G protein-coupled receptor 84 | 0.031 | ||
| Clec5a | C-type lectin domain family 5, member a | 0.031 | ||
| Apobr | apolipoprotein B receptor | 0.027 | ||
| Cd300ld | CD300 molecule-like family member d | 0.026 | ||
| Igsf6 | immunoglobulin superfamily, member 6 | 0.026 | ||
| AF251705 | cDNA sequence AF251705 | 0.024 | Mouse | |
| Siglece | sialic acid binding Ig-like lectin E | 0.023 | ||
| Ptprz1 | protein tyrosine phosphatase, receptor type Z, polypeptide 1 | 0.023 | ||
| P2ry13 | purinergic receptor P2Y, G-protein coupled 13 | 0.023 | Mouse Rat | |
| Tmprss2 | transmembrane protease, serine 2 | 0.021 | ||
| Slamf8 | SLAM family member 8 | 0.021 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.021 | ||
| P2rx3 | purinergic receptor P2X, ligand-gated ion channel, 3 | 0.020 | Mouse | |
| March1 | membrane-associated ring finger (C3HC4) 1 | 0.020 | ||
| 5430435G22Rik | RIKEN cDNA 5430435G22 gene | 0.020 | ||
| AI447881 | expressed sequence AI447881 | 0.020 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.020 | ||
| Pilrb1 | paired immunoglobin-like type 2 receptor beta 1 | 0.019 | ||
| C3ar1 | complement component 3a receptor 1 | 0.019 | ||
| Fcgr4 | Fc receptor, IgG, low affinity IV | 0.019 | ||
| 4632428N05Rik | RIKEN cDNA 4632428N05 gene | 0.019 | ||
| Fpr1 | formyl peptide receptor 1 | 0.019 | ||
| Hk3 | hexokinase 3 | 0.018 | ||
| Btk | Bruton agammaglobulinemia tyrosine kinase | 0.017 | ||
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.017 | ||
| Mmp8 | matrix metallopeptidase 8 | 0.017 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.016 | ||
| Treml4 | triggering receptor expressed on myeloid cells-like 4 | 0.015 | ||
| Il1f9 | interleukin 1 family, member 9 | 0.015 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.015 | ||
| Gpr35 | G protein-coupled receptor 35 | 0.015 | ||
| Trem1 | triggering receptor expressed on myeloid cells 1 | 0.015 | ||
| Nfam1 | Nfat activating molecule with ITAM motif 1 | 0.015 | ||
| Gjb6 | gap junction protein, beta 6 | 0.015 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.015 | ||
| Emr4 | EGF-like module containing, mucin-like, hormone receptor-like sequence 4 | 0.014 | ||
| Havcr2 | hepatitis A virus cellular receptor 2 | 0.014 | ||
| Gabrb2 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 | 0.013 | ||
| Myo1f | myosin IF | 0.013 | ||
| Asprv1 | aspartic peptidase, retroviral-like 1 | 0.013 | ||
| Sash3 | SAM and SH3 domain containing 3 | 0.013 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.013 | ||
| Tlr13 | toll-like receptor 13 | 0.013 | ||
| Il1a | interleukin 1 alpha | 0.013 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.012 | ||
| Cd300lb | CD300 antigen like family member B | 0.012 | Mouse | |
| Clec4a3 | C-type lectin domain family 4, member a3 | 0.012 | ||
| C5ar1 | complement component 5a receptor 1 | 0.012 | ||
| Csad | cysteine sulfinic acid decarboxylase | 0.012 | ||
| Kcnb1 | potassium voltage gated channel, Shab-related subfamily, member 1 | 0.012 | ||
| 1810033B17Rik | RIKEN cDNA 1810033B17 gene | 0.012 | ||
| Trem2 | triggering receptor expressed on myeloid cells 2 | 0.012 | Mouse | |
| Clec4d | C-type lectin domain family 4, member d | 0.012 | ||
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.011 | ||
| Alox5ap | arachidonate 5-lipoxygenase activating protein | 0.011 | ||
| Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.011 | ||
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.011 | ||
| Cd84 | CD84 antigen | 0.011 | ||
| Ncf1 | neutrophil cytosolic factor 1 | 0.011 | ||
| Itgam | integrin alpha M | 0.011 | ||
| Itgb3 | integrin beta 3 | 0.011 | ||
| Cyth4 | cytohesin 4 | 0.010 | ||
| Rnf112 | ring finger protein 112 | 0.010 | ||
| Tnfaip8l2 | tumor necrosis factor, alpha-induced protein 8-like 2 | 0.010 | ||
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.010 |