IMP
Process View
nicotine metabolic process
The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "nicotine metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Cyp2b1 | cytochrome P450, family 2, subfamily b, polypeptide 1 | 0.954 | Rat | |
| Cyp2d3 | cytochrome P450, family 2, subfamily d, polypeptide 3 | 0.807 | Rat | |
| Cyp2a1 | cytochrome P450, family 2, subfamily a, polypeptide 1 | 0.760 | Rat | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.728 | ||
| Cyp2d2 | cytochrome P450, family 2, subfamily d, polypeptide 2 | 0.659 | Rat | |
| Sult1e1 | sulfotransferase family 1E, estrogen-preferring, member 1 | 0.603 | ||
| Cyp2c13 | cytochrome P450, family 2, subfamily c, polypeptide 13 | 0.599 | ||
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.580 | ||
| Cyp3a23/3a1 | cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 | 0.568 | ||
| Abcc6 | ATP-binding cassette, subfamily C (CFTR/MRP), member 6 | 0.549 | ||
| Cyp3a18 | cytochrome P450, family 3, subfamily a, polypeptide 18 | 0.485 | ||
| Gnmt | glycine N-methyltransferase | 0.465 | ||
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.427 | ||
| A1i3 | alpha-1-inhibitor III | 0.419 | ||
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.354 | Rat | |
| Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | 0.334 | ||
| Ugt2b5 | UDP glucuronosyltransferase 2 family, polypeptide B5 | 0.303 | ||
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.285 | ||
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.255 | ||
| Dpys | dihydropyrimidinase | 0.243 | ||
| Sult1c2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.234 | ||
| Cyp4a8 | cytochrome P450, family 4, subfamily a, polypeptide 8 | 0.223 | ||
| Kcnj1 | potassium inwardly-rectifying channel, subfamily J, member 1 | 0.199 | ||
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.190 | ||
| Cyp2f4 | cytochrome P450, family 2, subfamily f, polypeptide 4 | 0.167 | Rat | |
| Otc | ornithine carbamoyltransferase | 0.166 | ||
| Cyp2b2 | cytochrome P450, family 2, subfamily b, polypeptide 2 | 0.152 | ||
| Cyp1a1 | cytochrome P450, family 1, subfamily a, polypeptide 1 | 0.151 | ||
| Olr1701 | olfactory receptor 1701 | 0.137 | ||
| LOC100365112 | carboxylesterase-like | 0.130 | ||
| Apob | apolipoprotein B | 0.129 | ||
| Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.125 | ||
| Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 0.122 | ||
| Crygf | crystallin, gamma F | 0.120 | ||
| Ugt2b37 | UDP-glucuronosyltransferase 2 family, member 37 | 0.103 | ||
| Cyp2b3 | cytochrome P450, family 2, subfamily b, polypeptide 3 | 0.093 | ||
| Cyp4f1 | cytochrome P450, family 4, subfamily f, polypeptide 1 | 0.088 | ||
| Olr1469 | olfactory receptor Olr1469 | 0.087 | ||
| Cyp2c22 | cytochrome P450, family 2, subfamily c, polypeptide 22 | 0.085 | Rat | |
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.079 | ||
| Azgp1 | alpha-2-glycoprotein 1, zinc-binding | 0.073 | ||
| Trhr2 | thyrotropin releasing hormone receptor 2 | 0.066 | ||
| Sstr4 | somatostatin receptor 4 | 0.065 | ||
| Cyp4f4 | cytochrome P450, family 4, subfamily f, polypeptide 4 | 0.063 | ||
| Slc23a1 | solute carrier family 23 (nucleobase transporters), member 1 | 0.061 | ||
| Gsta2 | glutathione S-transferase A2 | 0.058 | ||
| Mip | major intrinsic protein of lens fiber | 0.056 | ||
| Ces1c | carboxylesterase 1C | 0.053 | ||
| Gpr182 | G protein-coupled receptor 182 | 0.047 | ||
| Inmt | indolethylamine N-methyltransferase | 0.046 | ||
| Cyp2a2 | cytochrome P450, family 2, subfamily a, polypeptide 2 | 0.045 | Rat | |
| Cyp4a2 | cytochrome P450, family 4, subfamily a, polypeptide 2 | 0.044 | ||
| Abcb11 | ATP-binding cassette, subfamily B (MDR/TAP), member 11 | 0.044 | ||
| Mettl7b | methyltransferase like 7B | 0.042 | ||
| Slco1b3 | solute carrier organic anion transporter family, member 1b3 | 0.041 | ||
| Olr59 | olfactory receptor 59 | 0.041 | ||
| LOC100361864 | UDP-glucuronosyltransferase 2B3-like | 0.041 | ||
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.037 | ||
| Olr37 | olfactory receptor 37 | 0.037 | ||
| Fgfr4 | fibroblast growth factor receptor 4 | 0.036 | ||
| Cyp4f6 | cytochrome P450, family 4, subfamily f, polypeptide 6 | 0.034 | ||
| Fdxr | ferredoxin reductase | 0.032 | ||
| Haao | 3-hydroxyanthranilate 3,4-dioxygenase | 0.031 | ||
| Ces1e | carboxylesterase 1E | 0.030 | ||
| Apoa2 | apolipoprotein A-II | 0.030 | ||
| Cyp2c23 | cytochrome P450, family 2, subfamily c, polypeptide 23 | 0.030 | Rat | |
| Gcm1 | glial cells missing homolog 1 (Drosophila) | 0.029 | ||
| Mosc1 | MOCO sulphurase C-terminal domain containing 1 | 0.028 | ||
| Colq | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 0.028 | ||
| Adh1 | alcohol dehydrogenase 1 (class I) | 0.027 | ||
| F9 | coagulation factor IX | 0.027 | ||
| Hoxa2 | homeo box A2 | 0.026 | ||
| Adhfe1 | alcohol dehydrogenase, iron containing, 1 | 0.026 | ||
| Slco1a4 | solute carrier organic anion transporter family, member 1a4 | 0.026 | ||
| Dhfr | dihydrofolate reductase | 0.026 | ||
| Pon1 | paraoxonase 1 | 0.025 | ||
| Svs3a | seminal vesicle secretory protein 3A | 0.025 | ||
| Cyp3a9 | cytochrome P450, family 3, subfamily a, polypeptide 9 | 0.024 | ||
| Selp | selectin P | 0.024 | ||
| Il13 | interleukin 13 | 0.024 | ||
| Sult1a1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.023 | ||
| Hsd17b6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.023 | ||
| Olr1362 | olfactory receptor 1362 | 0.023 | ||
| Pigr | polymeric immunoglobulin receptor | 0.023 | ||
| Cyp2d4 | cytochrome P450, family 2, subfamily d, polypeptide 4 | 0.023 | Rat | |
| Nat8 | N-acetyltransferase 8 | 0.023 | ||
| Srd5a1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 0.023 | ||
| RT1-M5 | RT1 class Ib, locus M5 | 0.022 | ||
| Ces1d | carboxylesterase 1D | 0.022 | ||
| Mtrr | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.022 | ||
| Rxrg | retinoid X receptor gamma | 0.022 | ||
| Ust5r | integral membrane transport protein UST5r | 0.021 | ||
| LOC293989 | cytochrome P450-like | 0.020 | Rat | |
| Olr825 | olfactory receptor 825 | 0.020 | ||
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.019 | ||
| Asgr1 | asialoglycoprotein receptor 1 | 0.019 | ||
| Car5a | carbonic anhydrase 5a, mitochondrial | 0.019 | ||
| Cml3 | camello-like 3 | 0.018 | ||
| LOC299282 | Serine protease inhibitor | 0.018 | ||
| MGC114440 | similar to RIKEN cDNA 4930555I21 | 0.018 | ||
| Dpyd | dihydropyrimidine dehydrogenase | 0.017 | ||
| Rag1 | recombination activating gene 1 | 0.017 | ||
| Klkb1 | kallikrein B, plasma 1 | 0.016 | ||
| Rgn | regucalcin (senescence marker protein-30) | 0.016 | ||
| Taf6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor | 0.016 | ||
| LOC494499 | LOC494499 protein | 0.016 | ||
| Aqp9 | aquaporin 9 | 0.015 | ||
| Hsd3b5 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 | 0.015 | ||
| Slc22a8 | solute carrier family 22 (organic anion transporter), member 8 | 0.015 | ||
| Kcnh4 | potassium voltage-gated channel, subfamily H (eag-related), member 4 | 0.014 | ||
| Hpd | 4-hydroxyphenylpyruvate dioxygenase | 0.014 | ||
| Mgst2 | microsomal glutathione S-transferase 2 | 0.014 | ||
| Olr837 | olfactory receptor 837 | 0.014 | ||
| Cyp2j3 | cytochrome P450, family 2, subfamily j, polypeptide 3 | 0.014 | ||
| Afm | afamin | 0.013 | ||
| Fabp1 | fatty acid binding protein 1, liver | 0.013 | ||
| Gsta5 | glutathione S-transferase Yc2 subunit | 0.013 | ||
| Atp4b | ATPase, H+/K+ exchanging, beta polypeptide | 0.013 | ||
| Ces1f | carboxylesterase 1F | 0.013 | ||
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.013 | ||
| Ghrhr | growth hormone releasing hormone receptor | 0.013 | ||
| Pck1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.013 | ||
| Cyp2c11 | cytochrome P450, subfamily 2, polypeptide 11 | 0.013 | Rat | |
| Cyp27a1 | cytochrome P450, family 27, subfamily a, polypeptide 1 | 0.012 | ||
| Naalad2 | N-acetylated alpha-linked acidic dipeptidase 2 | 0.012 | ||
| Il8ra | interleukin 8 receptor, alpha | 0.012 | ||
| L3mbtl3 | l(3)mbt-like 3 (Drosophila) | 0.012 | ||
| Gulo | gulonolactone (L-) oxidase | 0.012 | ||
| Prol1 | proline rich, lacrimal 1 | 0.012 | ||
| Akr1c1 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 0.012 | ||
| Sval2 | seminal vesicle antigen-like 2 | 0.011 | ||
| Gstm2 | glutathione S-transferase mu 2 | 0.011 | ||
| Rpusd3 | RNA pseudouridylate synthase domain containing 3 | 0.011 | ||
| Il1rl2 | interleukin 1 receptor-like 2 | 0.011 | ||
| Bucs1 | butyryl Coenzyme A synthetase 1 | 0.011 | ||
| Mks1 | Meckel syndrome, type 1 | 0.011 | ||
| Fgb | fibrinogen beta chain | 0.011 | ||
| Aadac | arylacetamide deacetylase (esterase) | 0.011 | ||
| Cyp2b15 | cytochrome P450, family 2, subfamily b, polypeptide 15 | 0.011 | Rat | |
| Akr1c14 | aldo-keto reductase family 1, member C14 | 0.011 | ||
| LOC680367 | similar to Urinary protein 3 precursor (RUP-3) | 0.011 | ||
| Kynu | kynureninase (L-kynurenine hydrolase) | 0.010 | ||
| Gif | gastric intrinsic factor | 0.010 |