IMP

Process View

Rattus norvegicus

1 genes annotated in rat

Multi-species View

regulation of isotype switching

GO:0045191

Any process that modulates the frequency, rate or extent of isotype switching.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of isotype switching"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of isotype switching" (in gray)

Name	Description	Probability	Func Analog Organism
Cd37	CD37 molecule	0.132
Cd53	Cd53 molecule	0.068
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.063
Cxcr4	chemokine (C-X-C motif) receptor 4	0.053
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.047
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.045
Syk	spleen tyrosine kinase	0.043
Bin2	bridging integrator 2	0.037
Apol3	apolipoprotein L, 3	0.034
Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	0.034
Hck	hemopoietic cell kinase	0.033
Slfn2	schlafen 2	0.032
Arhgap4	Rho GTPase activating protein 4	0.030
Il2rg	interleukin 2 receptor, gamma	0.030
Casp1	caspase 1	0.029
Myh9	myosin, heavy chain 9, non-muscle	0.029
Arl5c	ADP-ribosylation factor-like 5C	0.028
Cd247	Cd247 molecule	0.027
Pcgf6	polycomb group ring finger 6	0.026
Ctse	cathepsin E	0.025
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.025
Mca32	mast cell antigen 32	0.025
Il1b	interleukin 1 beta	0.025
Cd2	Cd2 molecule	0.025
Lcp2	lymphocyte cytosolic protein 2	0.025
Arhgap25	Rho GTPase activating protein 25	0.024
RT1-Db1	RT1 class II, locus Db1	0.024
Vav1	vav 1 guanine nucleotide exchange factor	0.023
Vcam1	vascular cell adhesion molecule 1	0.023
Trim47	tripartite motif-containing 47	0.022
Anpep	alanyl (membrane) aminopeptidase	0.022
Zc3h7a	zinc finger CCCH type containing 7 A	0.021
Ptafr	platelet-activating factor receptor	0.021
Il16	interleukin 16	0.020
Gpsm3	G-protein signaling modulator 3 (AGS3-like, C. elegans)	0.020
Prpf38a	PRP38 pre-mRNA processing factor 38 (yeast) domain containing A	0.020
Rcsd1	RCSD domain containing 1	0.018
Bak1	BCL2-antagonist/killer 1	0.018
Tnfrsf14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.018	Rat
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.017
LOC100363783	rCG53773-like	0.017
Tlr7	toll-like receptor 7	0.017
Cd80	Cd80 molecule	0.017
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.017
Ptpro	protein tyrosine phosphatase, receptor type, O	0.017
Mmp8	matrix metallopeptidase 8	0.017
Zyx	zyxin	0.016
Cd5	Cd5 molecule	0.016
Igsf6	immunoglobulin superfamily, member 6	0.016
Slc15a3	solute carrier family 15, member 3	0.016
Mcpt3	mast cell peptidase 3	0.016
Sell	selectin L	0.016
Cnr2	cannabinoid receptor 2 (macrophage)	0.016
Lst1	leukocyte specific transcript 1	0.016
Sipa1	signal-induced proliferation-associated 1	0.016
Reg1a	regenerating islet-derived 1 alpha	0.015
Yme1l1	YME1-like 1 (S. cerevisiae)	0.015
Sycp1	synaptonemal complex protein 1	0.015
Il7r	interleukin 7 receptor	0.015
Cd4	Cd4 molecule	0.015
Hsd17b1	hydroxysteroid (17-beta) dehydrogenase 1	0.015
Ets1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.015
Fosl1	fos-like antigen 1	0.015
Myo1g	myosin IG	0.015
Ube2d4	ubiquitin-conjugating enzyme E2D 4	0.015
Ccl3	chemokine (C-C motif) ligand 3	0.015
Alox5	arachidonate 5-lipoxygenase	0.015
ND4	NADH dehydrogenase subunit 4	0.015
Mmp12	matrix metallopeptidase 12	0.015
Sla	src-like adaptor	0.015
Cybb	cytochrome b-245, beta polypeptide	0.015
Ddx52	DEAD (Asp-Glu-Ala-Asp) box polypeptide 52	0.014
Npffr2	neuropeptide FF receptor 2	0.014
Sirpa	signal-regulatory protein alpha	0.014
Cd22	CD22 molecule	0.014
Ncr3	natural cytotoxicity triggering receptor 3	0.014
Csn1s1	casein alpha s1	0.014
Herc4	hect domain and RLD 4	0.014
Stat4	signal transducer and activator of transcription 4	0.014
Ccl4	chemokine (C-C motif) ligand 4	0.014
Laptm5	lysosomal protein transmembrane 5	0.014
Gpr114	G protein-coupled receptor 114	0.014
Il4ra	interleukin 4 receptor, alpha	0.014
LOC688276	similar to epidermodysplasia verruciformis 2	0.014
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.014
Vcan	versican	0.014
Fabp2	fatty acid binding protein 2, intestinal	0.013
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.013
Vom2r27	vomeronasal 2 receptor, 27	0.013
Calcb	calcitonin-related polypeptide, beta	0.013
Cd28	Cd28 molecule	0.013	Mouse
Cubn	cubilin (intrinsic factor-cobalamin receptor)	0.013
Il2rb	interleukin 2 receptor, beta	0.013
Accn5	amiloride-sensitive cation channel 5, intestinal	0.013
Fmnl1	formin-like 1	0.013
Tpp2	tripeptidyl peptidase II	0.013
Ptpn7	protein tyrosine phosphatase, non-receptor type 7	0.013
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.013
Dusp4	dual specificity phosphatase 4	0.013
Expi	extracellular proteinase inhibitor	0.012
Ccl5	chemokine (C-C motif) ligand 5	0.012
Ripk3	receptor-interacting serine-threonine kinase 3	0.012
Fabp9	fatty acid binding protein 9, testis	0.012
Slc7a9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9	0.012
Cyp2c12	cytochrome P450, family 2, subfamily c, polypeptide 12	0.012
Cfp	complement factor properdin	0.012
Skap2	src kinase associated phosphoprotein 2	0.012
Notch3	Notch homolog 3 (Drosophila)	0.012
Mobkl2a	MOB1, Mps One Binder kinase activator-like 2A (yeast)	0.012
Ppard	peroxisome proliferator-activated receptor delta	0.012
Prkcd	protein kinase C, delta	0.011
Dok2	docking protein 2	0.011
Cd44	Cd44 molecule	0.011
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.011
Hcn4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.011
Adrb2	adrenergic, beta-2-, receptor, surface	0.011
Ugcg	UDP-glucose ceramide glucosyltransferase	0.011
Tdh	L-threonine dehydrogenase	0.011
Clec9a	C-type lectin domain family 9, member a	0.011
Pim1	pim-1 oncogene	0.011
Gpx2	glutathione peroxidase 2	0.011
Fgfr1	Fibroblast growth factor receptor 1	0.011
Raver1	ribonucleoprotein, PTB-binding 1	0.011
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.011
Ly86	lymphocyte antigen 86	0.011
Foxa3	forkhead box A3	0.011
Tfec	transcription factor EC	0.011
Trpm8	transient receptor potential cation channel, subfamily M, member 8	0.011
Hoxb5	homeo box B5	0.011
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.011
Mov10	Moloney leukemia virus 10	0.011
Abi3	ABI family, member 3	0.011
Spn	sialophorin	0.011
Sgp158	proline-rich glycoprotein (sgp158)	0.011
Uts2	urotensin 2	0.011
Trpv2	transient receptor potential cation channel, subfamily V, member 2	0.010
Sec31a	SEC31 homolog A (S. cerevisiae)	0.010
Smek2	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	0.010
Mettl14	methyltransferase like 14	0.010
Abcb4	ATP-binding cassette, subfamily B (MDR/TAP), member 4	0.010
Nos3	nitric oxide synthase 3, endothelial cell	0.010
Zbp1	Z-DNA binding protein 1	0.010
Plek	pleckstrin	0.010
Hbg1	hemoglobin, gamma A	0.010
RT1-Ba	RT1 class II, locus Ba	0.010
Irf5	interferon regulatory factor 5	0.010
N5	DNA binding protein N5	0.010
Scn11a	sodium channel, voltage-gated, type XI, alpha	0.010
Col12a1	collagen, type XII, alpha 1	0.010