IMP

Process View

Rattus norvegicus

13 genes annotated in rat

cell killing

GO:0001906

Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell killing"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell killing" (in gray)

Name	Description	Probability	Func Analog Organism
RT1-EC2	RT1 class Ib, locus EC2	0.817
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.564
Hsph1	heat shock 105/110 protein 1	0.385
Gzmk	granzyme K	0.310
Gzmb	granzyme B	0.194	Mouse
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.159
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.141
B2m	beta-2 microglobulin	0.140	Mouse
Oas1a	2'-5' oligoadenylate synthetase 1A	0.137
Neurl3	neuralized homolog 3 (Drosophila)	0.119
RT1-Cl	RT1 class Ib, locus Cl	0.113
Cd2	Cd2 molecule	0.090
Cxcl10	chemokine (C-X-C motif) ligand 10	0.084
RT1-CE12	RT1 class I, locus CE12	0.073
Atf3	activating transcription factor 3	0.064
Rt1.aa	MHC class I RT1.Aa alpha-chain	0.063
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.063
RT1-Da	RT1 class II, locus Da	0.062
Nkg7	natural killer cell group 7 sequence	0.060
Psmb8	proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)	0.060
Spn	sialophorin	0.059
Cd8a	CD8a molecule	0.039
Arhgap4	Rho GTPase activating protein 4	0.037
Prf1	perforin 1 (pore forming protein)	0.037
Ly6al	lymphocyte antigen 6 complex, locus A-like	0.036
Mcpt8	mast cell protease 8	0.034
RGD1304644	similar to RIKEN cDNA 2310046K01	0.033
Ccl7	chemokine (C-C motif) ligand 7	0.032
Kmo	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.032
Fut2	fucosyltransferase 2 (secretor status included)	0.031
Sell	selectin L	0.031
Xcl1	chemokine (C motif) ligand 1	0.029	Human
Sept1	septin 1	0.026
Ccl5	chemokine (C-C motif) ligand 5	0.026
Cd53	Cd53 molecule	0.026
Gimap4	GTPase, IMAP family member 4	0.026
Il7r	interleukin 7 receptor	0.025
Cd247	Cd247 molecule	0.024
Hspb1	heat shock protein 1	0.023
Gbp2	guanylate binding protein 2	0.023
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.023
LOC100364500	RT1 class I, locus CE11-like	0.022
Tfec	transcription factor EC	0.022
Ripk3	receptor-interacting serine-threonine kinase 3	0.022	Mouse
Igsf6	immunoglobulin superfamily, member 6	0.022
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.021
Mx1	myxovirus (influenza virus) resistance 1	0.021
Dctn4	dynactin 4	0.021
Apoe	apolipoprotein E	0.020
Ugt1a7c	UDP glucuronosyltransferase 1 family, polypeptide A7C	0.019
Tcrb	T-cell receptor beta chain	0.019
Fam70b	family with sequence similarity 70, member B	0.018
Ubb	ubiquitin B	0.018
Rgs1	regulator of G-protein signaling 1	0.018
Il2rb	interleukin 2 receptor, beta	0.018
Casp1	caspase 1	0.018
Ly6c	Ly6-C antigen	0.018
Uba7	ubiquitin-like modifier activating enzyme 7	0.017
Fcgr3a	Fc fragment of IgG, low affinity IIIa, receptor	0.017
Plcg2	phospholipase C, gamma 2	0.017
LOC100364854	similar to RIKEN cDNA A430107P09 gene-like	0.016
RT1-S3	RT1 class Ib, locus S3	0.016	Mouse Rat
Mmp12	matrix metallopeptidase 12	0.016
Blnk	B-cell linker	0.016
Clec9a	C-type lectin domain family 9, member a	0.016	Rat
Il7	interleukin 7	0.015
Emcn	endomucin	0.015
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.015
Pim1	pim-1 oncogene	0.015
Rhoh	ras homolog gene family, member H	0.015
Il2rg	interleukin 2 receptor, gamma	0.015
Msx2	msh homeobox 2	0.014
Gzma	granzyme A	0.014
Cd5	Cd5 molecule	0.014
Klrb1a	killer cell lectin-like receptor subfamily B, member 1A	0.014	Mouse
Actb	actin, beta	0.014
Klra5	killer cell lectin-like receptor, subfamily A, member 5	0.014	Rat
Slfn2	schlafen 2	0.014
Anxa2	annexin A2	0.014
Zap70	zeta-chain (TCR) associated protein kinase	0.013
Slc22a25	solute carrier family 22, member 25	0.013
Ptpre	protein tyrosine phosphatase, receptor type, E	0.013
LOC100363783	rCG53773-like	0.012
Cd3g	CD3 molecule, gamma	0.012
Irf2	interferon regulatory factor 2	0.012
Ddr1	discoidin domain receptor tyrosine kinase 1	0.012
Ptprcap	protein tyrosine phosphatase, receptor type, C-associated protein	0.012
Il10	interleukin 10	0.012
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.012
Cd8b	CD8b molecule	0.012
RT1-N3	RT1 class Ib, locus N3	0.012	Rat
Cxcl9	chemokine (C-X-C motif) ligand 9	0.012
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.012
Arhgap15	Rho GTPase activating protein 15	0.011
Irf1	interferon regulatory factor 1	0.011
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.011
Vom1r93	vomeronasal 1 receptor 93	0.011
Ccr2	chemokine (C-C motif) receptor 2	0.011
Aif1	allograft inflammatory factor 1	0.010
LOC100364485	mCG1051031-like	0.010
RT1-M3-1	RT1 class Ib, locus M3, gene 1	0.010	Rat
Hcst	hematopoietic cell signal transducer	0.010