IMP
Process View
dna repair
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dna repair"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.248 | ||
| pola2 | polymerase (DNA directed), alpha 2 | 0.245 | ||
| wdr76 | WD repeat domain 76 | 0.089 | ||
| chek1 | CHK1 checkpoint homolog (S. pombe) | 0.087 | Human Mouse | |
| slbp | stem-loop binding protein | 0.061 | ||
| ddb2 | damage-specific DNA binding protein 2 | 0.060 | Human Mouse | |
| nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.058 | ||
| fen1 | flap structure-specific endonuclease 1 | 0.056 | Yeast Mouse | |
| cry5 | cryptochrome 5 | 0.052 | ||
| pcna | proliferating cell nuclear antigen | 0.042 | Human Mouse | |
| mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.036 | Yeast | |
| brca2 | breast cancer 2, early onset | 0.035 | ||
| hat1 | histone acetyltransferase 1 | 0.032 | ||
| palb2 | partner and localizer of BRCA2 | 0.032 | ||
| si:dkey-258f14.5 | si:dkey-258f14.5 | 0.029 | ||
| dnmt1 | DNA (cytosine-5-)-methyltransferase 1 | 0.027 | ||
| zgc:101661 | zgc:101661 | 0.023 | ||
| fancl | Fanconi anemia, complementation group L | 0.023 | Human | |
| hirip3 | HIRA interacting protein 3 | 0.022 | ||
| psmd12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.022 | ||
| tef | thyrotroph embryonic factor | 0.021 | ||
| dut | dUTP pyrophosphatase | 0.021 | ||
| gins2 | GINS complex subunit 2 | 0.020 | ||
| suv39h1b | suppressor of variegation 3-9 homolog 1b | 0.018 | ||
| ube2i | ubiquitin-conjugating enzyme E2I | 0.018 | ||
| vcp | valosin containing protein | 0.018 | Human | |
| xpc | xeroderma pigmentosum, complementation group C | 0.018 | Mouse | |
| sass6 | spindle assembly 6 homolog (C. elegans) | 0.018 | ||
| zgc:56197 | zgc:56197 | 0.018 | ||
| psmc2 | proteasome (prosome, macropain) 26S subunit, ATPase 2 | 0.018 | ||
| fanci | Fanconi anemia, complementation group I | 0.018 | ||
| per2 | period homolog 2 (Drosophila) | 0.017 | ||
| cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae) | 0.016 | ||
| blmh | bleomycin hydrolase | 0.016 | ||
| rfc5 | replication factor C (activator 1) 5 | 0.016 | ||
| pola1 | polymerase (DNA directed), alpha 1 | 0.016 | Human Yeast | |
| mybl2 | myeloblastosis oncogene-like 2 | 0.014 | ||
| psmd6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.014 | ||
| hells | helicase, lymphoid-specific | 0.013 | ||
| cry-dash | cryptochrome DASH | 0.013 | ||
| msh2 | mutS homolog 2 (E. coli) | 0.013 | Human Yeast Mouse Worm | |
| cdk2 | cyclin-dependent kinase 2 | 0.013 | Yeast | |
| hmgb2b | high-mobility group box 2b | 0.013 | Human | |
| psmc6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.012 | ||
| hoxa13a | homeo box A13a | 0.012 | ||
| traip | TRAF-interacting protein | 0.012 | ||
| ywhaba | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a | 0.012 | ||
| eif4h | eukaryotic translation initiation factor 4h | 0.012 | ||
| asf1bb | ASF1 anti-silencing function 1 homolog Bb | 0.011 | ||
| anp32a | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.011 | ||
| psma6a | proteasome (prosome, macropain) subunit, alpha type, 6a | 0.011 | ||
| paxip1 | PAX interacting (with transcription-activation domain) protein 1 | 0.010 | ||
| psmd13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.010 | ||
| rap1a | RAP1A, member of RAS oncogene family | 0.010 | ||
| psmb3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.010 |