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Process View

Danio rerio

1 genes annotated in zebrafish

homologous chromosome segregation

The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "homologous chromosome segregation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "homologous chromosome segregation" (in gray)

Name	Description	Probability	Func Analog Organism
extl3	exostoses (multiple)-like 3	0.438
ccnb1	cyclin B1	0.347
sass6	spindle assembly 6 homolog (C. elegans)	0.187
ccnb2	cyclin B2	0.174
plk1	polo-like kinase 1 (Drosophila)	0.157
dusp6	dual specificity phosphatase 6	0.118
jag1b	jagged 1b	0.109
zgc:73142	zgc:73142	0.100
ppp3ca	protein phosphatase 3, catalytic subunit, alpha isozyme	0.093
csnk1db	casein kinase 1, delta b	0.089	Yeast
wu:fi04f09	wu:fi04f09	0.085
top2a	topoisomerase (DNA) II alpha	0.067
tctex1d1	Tctex1 domain containing 1	0.066
foxi1	forkhead box I1	0.065
atp6v0cb	ATPase, H+ transporting, lysosomal, V0 subunit c, b	0.062
ung	uracil-DNA glycosylase	0.060
ccna2	cyclin A2	0.055
csnk1g2a	casein kinase 1, gamma 2a	0.054
zfand5a	zinc finger, AN1-type domain 5a	0.053
satb2	SATB homeobox 2	0.051
bub3	BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)	0.049
birc5a	baculoviral IAP repeat-containing 5a	0.048
kif23	kinesin family member 23	0.043
aldocb	aldolase C, fructose-bisphosphate, b	0.042
cdca8	cell division cycle associated 8	0.041
tspan7b	tetraspanin 7b	0.041
rest	RE1-silencing transcription factor	0.041
rasl11b	RAS-like, family 11, member B	0.039
cdc25	cell division cycle 25 homolog	0.036
rasgef1ba	RasGEF domain family, member 1Ba	0.035
aurkb	aurora kinase B	0.034	Yeast
plk4	polo-like kinase 4 (Drosophila)	0.033
ncapd2	non-SMC condensin I complex, subunit D2	0.033
pou5f1	POU domain, class 5, transcription factor 1	0.031
zgc:55813	zgc:55813	0.031
gle1	GLE1 RNA export mediator homolog (yeast)	0.030
poc1a	POC1 centriolar protein homolog A (Chlamydomonas)	0.030
max	myc-associated factor X	0.029
etaa1	Ewing tumor-associated antigen 1	0.028
tob1a	transducer of ERBB2, 1a	0.028
brd2a	bromodomain-containing 2a	0.028
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.027
lrmp	lymphoid-restricted membrane protein	0.026
aurka	aurora kinase A	0.025	Yeast
LOC558023	hypothetical protein LOC558023	0.025
gnb1a	guanine nucleotide binding protein (G protein), beta polypeptide 1a	0.025
tef	thyrotroph embryonic factor	0.024
pkm2a	pyruvate kinase, muscle, a	0.024
syt11a	synaptotagmin XIa	0.023
cdc20	cell division cycle 20 homolog	0.023
bon	bonnie and clyde	0.023
zgc:113210	zgc:113210	0.023
csnk1da	casein kinase 1, delta a	0.022	Yeast
pane1	proliferation associated nuclear element	0.021
cobl	cordon-bleu homolog (mouse)	0.021
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.021
wnt3a	wingless-type MMTV integration site family, member 3A	0.021
melk	maternal embryonic leucine zipper kinase	0.021
ruvbl2	RuvB-like 2 (E. coli)	0.021
wnt9a	wingless-type MMTV integration site family, member 9A	0.021
ccne	cyclin E	0.020
tex10	testis expressed 10	0.020
zgc:110687	zgc:110687	0.020
nr1d2b	nuclear receptor subfamily 1, group D, member 2b	0.019
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.019
pcdh18b	protocadherin 18b	0.019
si:ch211-147d7.3	si:ch211-147d7.3	0.019
tshz1	teashirt family zinc finger 1	0.019
btg2	B-cell translocation gene 2	0.018
eomesa	eomesodermin homolog a	0.018
mycl1b	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian) b	0.017
slc1a2b	solute carrier family 1 (glial high affinity glutamate transporter), member 2b	0.017
fzd7b	frizzled homolog 7b	0.017
gapdhs	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.017
unc45a	unc-45 homolog A (C. elegans)	0.017
ska3	spindle and kinetochore associated complex subunit 3	0.016
spns2	spinster homolog 2 (Drosophila)	0.016
irf2bp2a	interferon regulatory factor 2 binding protein 2a	0.016
chsy1	chondroitin sulfate synthase 1	0.016
chuk	conserved helix-loop-helix ubiquitous kinase	0.016
ropn1l	ropporin 1-like	0.016
stil	TAL1 (SCL) interrupting locus	0.016
ndrg4	N-myc downstream regulated gene 4	0.016
wu:fb21f05	wu:fb21f05	0.016
aaas	achalasia, adrenocortical insufficiency, alacrimia	0.015
bactin2	bactin2	0.015
palb2	partner and localizer of BRCA2	0.014
si:dkey-177p2.6	si:dkey-177p2.6	0.014
ckbb	creatine kinase, brain b	0.014
etv5a	ets variant 5a	0.014
ercc2	excision repair cross-complementing rodent repair deficiency, complementation group 2	0.014
LOC100006857	engulfment and cell motility protein 2	0.014
nuf2	NUF2, NDC80 kinetochore complex component, homolog	0.014
sf3b1	splicing factor 3b, subunit 1	0.013
mus81	MUS81 endonuclease homolog (yeast)	0.013
kif2c	kinesin family member 2C	0.013
si:ch211-69g19.2	si:ch211-69g19.2	0.013
sh3gl2	SH3-domain GRB2-like 2	0.013
rchy1	ring finger and CHY zinc finger domain containing 1	0.013
sec61al1	Sec61 alpha like 1	0.012
igf2r	insulin-like growth factor 2 receptor	0.012
clstn1	calsyntenin 1	0.012
zgc:152925	zgc:152925	0.012
hoxd9a	homeo box D9a	0.012
pdlim7	PDZ and LIM domain 7	0.012
rbm4.1	RNA binding motif protein 4.1	0.012
si:ch211-158b22.2	si:ch211-158b22.2	0.012
hoxa10b	homeo box A10b	0.012
LOC557062	hypothetical protein LOC557062	0.012
lin28a	lin-28 homolog A (C. elegans)	0.012
spsb1	splA/ryanodine receptor domain and SOCS box containing 1	0.012
mpp2b	membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2b)	0.012
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.011
szl	sizzled	0.011
eno1	enolase 1, (alpha)	0.011
tacc3	transforming, acidic coiled-coil containing protein 3	0.011
ints6	integrator complex subunit 6	0.011
sgsm3	small G protein signaling modulator 3	0.011
cluap1	clusterin associated protein 1	0.011
oip5	opa interacting protein 5	0.011
map2k4b	mitogen-activated protein kinase kinase 4b	0.011
hoxa9b	homeo box A9b	0.011
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.011
sox32	SRY-box containing gene 32	0.011
hoxd11a	homeo box D11a	0.010
rorab	RAR-related orphan receptor A, paralog b	0.010
cdh1	cadherin 1, epithelial	0.010
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.010
calm1b	calmodulin 1b	0.010
nkd2	naked cuticle homolog 2 and naked 2a	0.010
vasa	vasa homolog	0.010
midn	midnolin	0.010
polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.010