IMP

Process View

Danio rerio

13 genes annotated in zebrafish

response to lipopolysaccharide

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to lipopolysaccharide"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to lipopolysaccharide" (in gray)

Name	Description	Probability	Func Analog Organism
socs3a	suppressor of cytokine signaling 3a	0.429	Rat
cav1	caveolin 1	0.363
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.296	Mouse
tlr3	toll-like receptor 3	0.129
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.112	Mouse
stat3	signal transduction and activation of transcription 3	0.111
LOC557072	caspase recruitment domain-containing protein 11-like	0.104
pdlim1	PDZ and LIM domain 1 (elfin)	0.100
il6st	interleukin 6 signal transducer	0.100
mapk3	mitogen-activated protein kinase 3	0.098	Mouse
hspd1	heat shock 60kD protein 1 (chaperonin)	0.089
hspa5	heat shock protein 5	0.086
gli1	GLI-Kruppel family member 1	0.081
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.068
atf3	activating transcription factor 3	0.063
lrrc33	leucine rich repeat containing 33	0.054
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.053
tnfsf10l2	tumor necrosis factor (ligand) superfamily, member 10 like 2	0.052	Zebrafish
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.051	Mouse
bmp4	bone morphogenetic protein 4	0.050
mmp9	matrix metalloproteinase 9	0.049
flh	floating head	0.049
junb	jun B proto-oncogene	0.049
mib	mind bomb	0.048
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.048
hsd3b1	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	0.047
caspa	caspase a	0.043
junbl	jun B proto-oncogene, like	0.041
nod1	nucleotide-binding oligomerization domain containing 1	0.040
tnfrsfa	tumor necrosis factor receptor superfamily, member a	0.040
lhcgr	luteinizing hormone/choriogonadotropin receptor	0.040
il1b	interleukin 1, beta and interleukin 1, beta	0.038
epas1b	endothelial PAS domain protein 1b	0.037
cd63	Cd63 antigen	0.037
fzd7b	frizzled homolog 7b	0.034
cyp11a1	cytochrome P450, subfamily XIA, polypeptide 1	0.032	Rat
bmp2b	bone morphogenetic protein 2b	0.032
il8	interleukin 8	0.032
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.030
krml2.2	Kreisler (mouse) maf-related leucine zipper homolog 2.2	0.030
clic2	chloride intracellular channel 2	0.030
timp2b	tissue inhibitor of metalloproteinase 2b	0.029
ef1a	elongation factor 1-alpha	0.029
ptger4b	prostaglandin E receptor 4 (subtype EP4) b	0.027	Mouse
zfpl1	zinc finger protein-like 1	0.027
ctsl1b	cathepsin L, 1 b	0.026
nos2a	nitric oxide synthase 2a, inducible	0.026
mapk8b	mitogen-activated protein kinase 8b	0.025	Human
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.025
fcho2	FCH domain only 2	0.025
acvr2a	activin receptor IIa	0.025
vcana	versican a	0.024
nanos3	nanos homolog 3	0.024
fbn2b	fibrillin 2b	0.024
pycard	PYD and CARD domain containing	0.024	Human
pth1a	parathyroid hormone 1a	0.024
igf1	insulin-like growth factor 1	0.023
ctsl1a	cathepsin L, 1 a	0.023
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.023
fryl	furry homolog-like (Drosophila)	0.023
mcl1a	myeloid cell leukemia sequence 1a	0.022
casrl	calcium-sensing receptor, like	0.022
nrg1	neuregulin 1	0.022
khdrbs1a	KH domain containing, RNA binding, signal transduction associated 1a	0.021
alcama	activated leukocyte cell adhesion molecule a	0.021
klf2a	Kruppel-like factor 2a	0.021
sparc	secreted acidic cysteine rich glycoprotein	0.021	Rat
cyt1	type I cytokeratin, enveloping layer	0.021
fosl2	fos-like antigen 2	0.021
cdx4	caudal type homeo box transcription factor 4	0.021
jun	jun proto-oncogene	0.020	Rat
rag1	recombination activating gene 1	0.020
rargb	retinoic acid receptor, gamma b	0.020
dlx5a	distal-less homeobox gene 5a	0.020
grna	granulin a	0.020
plagl2	pleiomorphic adenoma gene-like 2	0.020
angptl1	angiopoietin-like 1	0.019
skia	nuclear oncoprotein skia	0.019
si:ch211-195h23.3	si:ch211-195h23.3	0.019
stc1l	stanniocalcin 1, like	0.019
tlr2	toll-like receptor 2	0.019
LOC566708	FL cytokine receptor-like	0.019
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.019
oep	one-eyed pinhead	0.018
hcrt	hypocretin (orexin) neuropeptide precursor	0.018
col1a1a	collagen, type I, alpha 1a	0.017
taf1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.017
anxa2a	annexin A2a	0.016
abcg2c	ATP-binding cassette, sub-family G (WHITE), member 2c	0.016
cpox	coproporphyrinogen oxidase	0.016
LOC100000332	e3 ubiquitin-protein ligase RNF182-like	0.016
spaw	southpaw	0.016
rhogb	ras homolog gene family, member Gb	0.016
hmgb2b	high-mobility group box 2b	0.016	Human
esd	esterase D/formylglutathione hydrolase	0.016
cldne	claudin e	0.015
serpinb1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.015
slc15a2	solute carrier family 15 (H+/peptide transporter), member 2	0.015
hbae1	hemoglobin alpha embryonic-1	0.015
ewsr1b	Ewing sarcoma breakpoint region 1b	0.014
hnrnpab	heterogeneous nuclear ribonucleoprotein A/B	0.014
ccr12.2	chemokine (C-C motif) receptor 12.2	0.014
zgc:153997	zgc:153997	0.014
cfl2l	cofilin 2, like	0.014
lpp	LIM domain containing preferred translocation partner in lipoma	0.014
igfbp1a	insulin-like growth factor binding protein 1a	0.014
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.014
card9	caspase recruitment domain family, member 9	0.014
fabp2	fatty acid binding protein 2, intestinal	0.014
nkx2.9	NK2 transcription factor related, locus 9 (Drosophila)	0.014
cygb2	cytoglobin 2	0.013
dlx3b	distal-less homeobox gene 3b	0.013
pcna	proliferating cell nuclear antigen	0.013
sod2	superoxide dismutase 2, mitochondrial	0.013
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.013
cdh1	cadherin 1, epithelial	0.013
igfbp2b	insulin-like growth factor binding protein 2b	0.013
icn	ictacalcin	0.013
prox1	prospero-related homeobox gene 1	0.013
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.013
slc2a1a	solute carrier family 2 (facilitated glucose transporter), member 1a	0.013
rxraa	retinoid X receptor, alpha a	0.013
anxa5b	annexin A5b	0.013
cpla2	cytosolic phospholipase a2	0.013
ptprc	protein tyrosine phosphatase, receptor type, C	0.012
scrib	scribbled homolog (Drosophila)	0.012
igfbp6b	insulin-like growth factor binding protein 6b	0.012
ifng1-2	interferon, gamma 1-2	0.012
cbr1l	carbonyl reductase 1-like	0.012
ctsba	cathepsin B, a	0.012
hspb1	heat shock protein, alpha-crystallin-related, 1	0.012
usp10	ubiquitin specific peptidase 10	0.012
epor	erythropoietin receptor	0.012
zgc:110340	zgc:110340	0.012
cx39.9	connexin 39.9	0.012
glcci1	glucocorticoid induced transcript 1	0.012
ptgs2a	prostaglandin-endoperoxide synthase 2a	0.011	Rat
sox9a	SRY-box containing gene 9a	0.011
col10a1	collagen, type X, alpha 1	0.011
dzip1	DAZ interacting protein 1	0.011
zgc:112425	zgc:112425	0.011
pdcd2	programmed cell death 2	0.011
ptgs1	prostaglandin-endoperoxide synthase 1	0.011
tp53	tumor protein p53	0.011
rbm4.2	RNA binding motif protein 4.2	0.011
apoeb	apolipoprotein Eb	0.011
wnt10a	wingless-type MMTV integration site family, member 10a	0.011
aldh2a	aldehyde dehydrogenase 2 family (mitochondrial)a	0.011
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.011
plcb3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.011
cyyr1	cysteine and tyrosine-rich protein 1	0.011
sdc2	syndecan 2	0.011
cxc46	CXC chemokine 46	0.011
igf3	insulin-like growth factor 3	0.011	Rat
mapk7	mitogen-activated protein kinase 7	0.011
hoxa11a	homeo box A11a	0.011
il22	interleukin 22	0.011
ifnphi1	interferon phi 1	0.011
pitx3	paired-like homeodomain transcription factor 3	0.011
abcc1	ATP-binding cassette, sub-family C, member 1	0.011
ranbp1	RAN binding protein 1	0.011
cadm3	cell adhesion molecule 3	0.011
egr2b	early growth response 2b	0.011
si:dkey-236e20.2	si:dkey-236e20.2	0.011
cbfb	core-binding factor, beta subunit	0.010
ptch2	patched 2	0.010
plcg1	phospholipase C, gamma 1	0.010
adrb2a	adrenergic receptor, beta 2a	0.010
brd2a	bromodomain-containing 2a	0.010
rxrga	retinoid x receptor, gamma a	0.010