IMP
Process View
dna integrity checkpoint
A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "dna integrity checkpoint"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| ywhabb | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b | 0.128 | ||
| ccnb1 | cyclin B1 | 0.108 | ||
| ywhaqb | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b | 0.062 | Yeast | |
| cul3a | cullin 3a | 0.046 | ||
| snrpd1 | small nuclear ribonucleoprotein D1 polypeptide | 0.044 | ||
| mcm5 | MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) | 0.041 | ||
| ccnb2 | cyclin B2 | 0.037 | ||
| cry3 | cryptochrome 3 | 0.037 | ||
| per2 | period homolog 2 (Drosophila) | 0.037 | ||
| id2a | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a | 0.036 | ||
| zc4h2 | zinc finger, C4H2 domain containing | 0.034 | ||
| plk1 | polo-like kinase 1 (Drosophila) | 0.032 | Human | |
| skp2 | S-phase kinase-associated protein 2 (p45) | 0.032 | ||
| ccnd1 | cyclin D1 | 0.029 | Human | |
| ywhaqa | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a | 0.029 | ||
| cstf1 | cleavage stimulation factor, 3' pre-RNA, subunit 1 | 0.029 | ||
| ccna2 | cyclin A2 | 0.026 | ||
| ywhae1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 | 0.026 | Fly | |
| npat | nuclear protein, ataxia-telangiectasia locus | 0.026 | ||
| stmn1b | stathmin 1b | 0.026 | ||
| xrcc6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.023 | ||
| tfam | transcription factor A, mitochondrial | 0.022 | ||
| celsr3 | cadherin, EGF LAG seven-pass G-type receptor 3 | 0.021 | ||
| wdr76 | WD repeat domain 76 | 0.021 | ||
| smc3 | structural maintenance of chromosomes 3 | 0.021 | ||
| slbp | stem-loop binding protein | 0.020 | ||
| cand1 | cullin-associated and neddylation-dissociated 1 | 0.020 | ||
| ddb2 | damage-specific DNA binding protein 2 | 0.019 | ||
| zff9 | zinc finger protein 9 | 0.018 | ||
| zgc:55701 | zgc:55701 | 0.018 | ||
| sass6 | spindle assembly 6 homolog (C. elegans) | 0.018 | ||
| prdm9 | PR domain containing 9 | 0.018 | ||
| hirip3 | HIRA interacting protein 3 | 0.017 | ||
| gtdc1 | glycosyltransferase-like domain containing 1 | 0.016 | ||
| hat1 | histone acetyltransferase 1 | 0.016 | ||
| sae1 | SUMO1 activating enzyme subunit 1 | 0.016 | ||
| kpna3 | karyopherin (importin) alpha 3 | 0.015 | Fly | |
| ywhai | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide | 0.015 | Yeast | |
| brd2a | bromodomain-containing 2a | 0.015 | ||
| ppp4ca | protein phosphatase 4 (formerly X), catalytic subunit a | 0.015 | Yeast | |
| orc6 | origin recognition complex, subunit 6 | 0.015 | ||
| zgc:56197 | zgc:56197 | 0.014 | ||
| anp32a | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.014 | ||
| ube2g2 | ubiquitin-conjugating enzyme E2G 2 | 0.014 | ||
| cry5 | cryptochrome 5 | 0.014 | ||
| pif1 | PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) | 0.014 | ||
| mpped2 | metallophosphoesterase domain containing 2 | 0.013 | ||
| si:dkey-57a22.11 | si:dkey-57a22.11 | 0.013 | ||
| ywhabl | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like | 0.013 | ||
| fen1 | flap structure-specific endonuclease 1 | 0.013 | ||
| rbb4 | retinoblastoma binding protein 4 | 0.013 | ||
| fzd7a | frizzled homolog 7a | 0.013 | ||
| rtkn2 | rhotekin 2 | 0.013 | ||
| otx1b | orthodenticle homolog 1b | 0.013 | ||
| ccnt2a | cyclin T2a | 0.013 | ||
| senp3a | SUMO1/sentrin/SMT3 specific peptidase 3a | 0.013 | ||
| kif23 | kinesin family member 23 | 0.012 | ||
| gmnn | geminin, DNA replication inhibitor | 0.012 | ||
| wdhd1 | WD repeat and HMG-box DNA binding protein 1 | 0.012 | ||
| clock3 | clock homolog 3 (mouse) | 0.012 | Human | |
| sumo3a | SMT3 suppressor of mif two 3 homolog 3a | 0.012 | ||
| wu:fb54a03 | wu:fb54a03 | 0.012 | ||
| ccne | cyclin E | 0.011 | ||
| nasp | nuclear autoantigenic sperm protein (histone-binding) | 0.011 | ||
| zgc:55448 | zgc:55448 | 0.011 | ||
| aggf1 | angiogenic factor with G patch and FHA domains 1 | 0.011 | ||
| atrx | alpha thalassemia/mental retardation syndrome X-linked homolog (human) | 0.011 | ||
| lrwd1 | leucine-rich repeats and WD repeat domain containing 1 | 0.011 | ||
| ptmaa | prothymosin, alpha a | 0.011 | ||
| zgc:111944 | zgc:111944 | 0.011 | ||
| morf4l1 | mortality factor 4 like 1 | 0.011 | ||
| ppp2r5eb | protein phosphatase 2, regulatory subunit B', epsilon isoform b | 0.011 | ||
| zgc:101819 | zgc:101819 | 0.011 | ||
| tubgcp2 | tubulin, gamma complex associated protein 2 | 0.011 | ||
| dnmt1 | DNA (cytosine-5-)-methyltransferase 1 | 0.011 | ||
| maea | macrophage erythroblast attacher | 0.011 | ||
| rrm1 | ribonucleotide reductase M1 polypeptide | 0.010 | ||
| zc3h13 | zinc finger CCCH-type containing 13 | 0.010 | ||
| wdr18 | WD repeat domain 18 | 0.010 | ||
| cops3 | COP9 constitutive photomorphogenic homolog subunit 3 | 0.010 | ||
| aurkb | aurora kinase B | 0.010 | Yeast | |
| smc1al | structural maintenance of chromosomes 1A, like | 0.010 |