The network for 'transmembrane receptor protein tyrosine kinase signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

transmembrane receptor protein tyrosine kinase signaling pathway

A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.

Drosophila melanogaster
Name Description Probability Func Analog Organism
InR Insulin-like receptor 0.991
rl rolled 0.984
Egfr Epidermal growth factor receptor 0.981
mbc myoblast city 0.975
rho rhomboid 0.971
phl pole hole 0.966
Rac1 CG2248 gene product from transcript CG2248-RA 0.950
drk downstream of receptor kinase 0.937
EcR Ecdysone receptor 0.912
Ras85D Ras oncogene at 85D 0.886
ttv tout-velu 0.868
sev sevenless 0.859
sty sprouty 0.819
hbs hibris 0.803
stumps CG31317 gene product from transcript CG31317-RC 0.799
put punt 0.791
babo baboon 0.751
caz cabeza 0.738
rpr reaper 0.709
Pten CG5671 gene product from transcript CG5671-RB 0.709
Lnk CG17367 gene product from transcript CG17367-RC 0.660
hipk homeodomain interacting protein kinase 0.653
Sin3A CG8815 gene product from transcript CG8815-RC 0.652
Akt1 CG4006 gene product from transcript CG4006-RA 0.650
Dsor1 Downstream of raf1 0.646
cnk connector enhancer of ksr 0.646
kni knirps 0.634
neur neuralized 0.634
ru roughoid 0.625
bowl brother of odd with entrails limited 0.608
dve defective proventriculus 0.598
Shc SHC-adaptor protein 0.590
bsk basket 0.589
aux auxillin 0.568
spi spitz 0.565
Ilp2 Insulin-like peptide 2 0.564
S6k RPS6-p70-protein kinase 0.542
shn schnurri 0.538
fkh fork head 0.538
Ilp5 Insulin-like peptide 5 0.538
kek1 kekkon-1 0.531
Src42A Src oncogene at 42A 0.530
btd buttonhead 0.529
Ubx Ultrabithorax 0.525
shg shotgun 0.512
NFAT NFAT homolog 0.491
svp seven up 0.483
eve even skipped 0.479
p38b CG7393 gene product from transcript CG7393-RA 0.476
LanB1 CG7123 gene product from transcript CG7123-RA 0.472
csw corkscrew 0.471
argos CG4531 gene product from transcript CG4531-RA 0.471
os outstretched 0.466
ro rough 0.462
btl breathless 0.461
sfl sulfateless 0.455
mew multiple edematous wings 0.453
slmb supernumerary limbs 0.435
skpA CG16983 gene product from transcript CG16983-RD 0.434
emc extra macrochaetae 0.426
fj four-jointed 0.414
Mad Mothers against dpp 0.407
hth homothorax 0.400
Tor Target of rapamycin 0.398
CG9139 CG9139 gene product from transcript CG9139-RA 0.391
Apc APC-like 0.391
Bx42 CG8264 gene product from transcript CG8264-RA 0.391
shi shibire 0.390
Rheb CG1081 gene product from transcript CG1081-RA 0.388
Nrt Neurotactin 0.387
CG5794 CG5794 gene product from transcript CG5794-RB 0.387
Myo31DF Myosin 31DF 0.383
C3G CG42328 gene product from transcript CG42328-RC 0.381
zfh1 Zn finger homeodomain 1 0.379
lqf liquid facets 0.376
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.375
pnt pointed 0.372
Ubqn Ubiquilin 0.371
Dad Daughters against dpp 0.368
Ide Insulin degrading metalloproteinase 0.366
sqh spaghetti squash 0.363
SoxN SoxNeuro 0.361
rap retina aberrant in pattern 0.355
rg rugose 0.355
Src64B Src oncogene at 64B 0.352
Tl Toll 0.351
mask multiple ankyrin repeats single KH domain 0.350
tsl torso-like 0.350
tkv thickveins 0.337
foxo forkhead box, sub-group O 0.336
Gyc76C Guanylyl cyclase at 76C 0.334
Bre1 CG10542 gene product from transcript CG10542-RA 0.331
Ulp1 CG12359 gene product from transcript CG12359-RA 0.326
gbb glass bottom boat 0.325
lkb1 CG9374 gene product from transcript CG9374-RJ 0.324
srp serpent 0.323
sav salvador 0.321
tok tolkin 0.318
CG10743 CG10743 gene product from transcript CG10743-RB 0.316
B-H1 BarH1 0.311
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
sem-5 Protein SEM-5 0.579
let-60 Protein LET-60 0.531
apc-2 Protein APC-2 0.486
pry-1 Protein PRY-1 0.441
nhr-67 Protein NHR-67 0.316
egl-15 Protein EGL-15 0.311
ceh-20 Protein CEH-20 0.305
plc-1 Protein PLC-1 0.304
lag-1 Protein LAG-1 0.224
daf-2 Protein DAF-2 0.224
egl-18 Protein EGL-18 0.216
hlh-30 Protein HLH-30 0.215
oac-46 Protein OAC-46 0.208
pxf-1 Protein PXF-1 0.202
acy-3 Protein ACY-3 0.171
bar-1 Protein BAR-1 0.160
akt-1 Protein AKT-1 0.139
acs-20 Protein ACS-20 0.136
cids-2 Protein CIDS-2 0.106
gpa-17 Protein GPA-17 0.102
daf-7 Protein DAF-7 0.102
ztf-27 Protein ZTF-27 0.099
unc-17 Protein UNC-17 0.093
K02G10.5 Protein K02G10.5 0.091
pal-1 Protein PAL-1 0.089
sma-6 Protein SMA-6 0.083
nlp-8 Protein NLP-8 0.076
tam-1 Protein TAM-1 0.076
pat-3 Protein PAT-3 0.075
rgl-1 Protein RGL-1 0.069
inx-1 Protein INX-1 0.068
K02A6.2 Protein K02A6.2 0.068
pmk-1 Protein PMK-1 0.068
ape-1 Protein APE-1 0.063
mig-2 Protein MIG-2 0.060
pde-2 Protein PDE-2 0.058
cav-2 Protein CAV-2 0.058
pept-3 Protein PEPT-3 0.056
ina-1 Protein INA-1 0.055
ZC506.1 Protein ZC506.1 0.054
T05A8.3 Protein T05A8.3 0.053
itr-1 Protein ITR-1 0.053
egl-30 Protein EGL-30 0.053
ccch-1 Protein CCCH-1 0.053
sms-1 Protein SMS-1 0.050
CELE_M05D6.3 Protein M05D6.3 0.050
miz-1 Protein MIZ-1 0.049
rgs-2 Protein RGS-2 0.048
C11E4.6 Protein C11E4.6 0.047
inx-19 Protein INX-19 0.047
tag-53 Protein TAG-53 0.046
ttyh-1 Protein TTYH-1 0.046
cfim-2 Protein CFIM-2 0.046
sup-17 Protein SUP-17 0.046
T19A5.3 Protein T19A5.3 0.045
egl-27 Protein EGL-27 0.045
F16F9.1 Protein F16F9.1 0.044
C05C9.1 Protein C05C9.1 0.044
hlh-14 Protein HLH-14 0.044
Y54G2A.11 Protein Y54G2A.11 0.044
dpy-31 Protein DPY-31 0.044
unc-6 Protein UNC-6 0.043
plc-3 Protein PLC-3 0.041
sax-3 Protein SAX-3 0.040
CELE_F23C8.6 Protein F23C8.6 0.040
clh-5 Protein CLH-5 0.040
che-14 Protein CHE-14 0.040
C26E1.2 Protein C26E1.2 0.039
dcn-1 Protein DCN-1 0.038
unc-83 Protein UNC-83 0.038
F14B8.6 Protein F14B8.6 0.038
let-19 Protein LET-19 0.037
hlh-1 Protein HLH-1 0.037
unc-43 Protein UNC-43 0.037
T05D4.3 Protein T05D4.3 0.037
vav-1 Protein VAV-1 0.036
F22D3.2 Protein F22D3.2 0.036
F09F9.4 Protein F09F9.4 0.036
nlp-12 Protein NLP-12 0.036
mep-1 Protein MEP-1 0.036
dnj-1 Protein DNJ-1 0.035
T01G1.2 Protein T01G1.2 0.035
daf-6 Protein DAF-6 0.035
glo-4 Protein GLO-4 0.035
mek-2 Protein MEK-2 0.034
tol-1 Protein TOL-1 0.034
lin-2 Protein LIN-2 0.033
madf-5 Protein MADF-5 0.033
lin-11 Protein LIN-11 0.033
kgb-1 Protein KGB-1 0.032
cyy-1 Protein CYY-1 0.032
atx-3 Protein ATX-3 0.032
nhx-9 Protein NHX-9 0.032
sel-8 Protein SEL-8 0.031
peb-1 Protein PEB-1 0.031
CELE_R10D12.1 Protein R10D12.1 0.031
vab-1 Protein VAB-1 0.031
acl-14 Protein ACL-14 0.031
F11E6.8 Protein F11E6.8 0.030
egl-8 Protein EGL-8 0.030
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Danio rerio
Name Description Probability Func Analog Organism
sox9a SRY-box containing gene 9a 0.986
fgf3 fibroblast growth factor 3 0.929
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.907
efnb2a ephrin B2a 0.824
bmp2a bone morphogenetic protein 2a 0.811
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.789
ptch2 patched 2 0.726
foxd3 forkhead box D3 0.607
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.564
ndr2 nodal-related 2 0.562
nrp1a neuropilin 1a 0.560
wnt4a wingless-type MMTV integration site family, member 4a 0.547
fgf8a fibroblast growth factor 8 a 0.544
lef1 lymphocyte enhancer binding factor 1 0.524
chd chordin 0.510
vcana versican a 0.510
fgfr3 fibroblast growth factor receptor 3 0.478
btg2 B-cell translocation gene 2 0.475
igf1rb insulin-like growth factor 1b receptor 0.463
wnt1 wingless-type MMTV integration site family, member 1 0.455
fgfr1b fibroblast growth factor receptor 1b 0.421
ephb4b eph receptor B4b 0.410
wnt3a wingless-type MMTV integration site family, member 3A 0.405
spry4 sprouty (Drosophila) homolog 4 0.394
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.381
amotl2a angiomotin like 2a 0.369
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.369
osr1 odd-skipped related 1 (Drosophila) 0.360
lft1 lefty1 0.358
tbx2b T-box 2b 0.358
tbx1 T-box 1 0.344
notch3 notch homolog 3 0.339
gngt2b guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b 0.339
emilin1a elastin microfibril interfacer 1a 0.334
atoh1a atonal homolog 1a 0.328
zbtb4 zinc finger and BTB domain containing 4 0.323
fbn2b fibrillin 2b 0.307
flt4 fms-related tyrosine kinase 4 0.296
igf1 insulin-like growth factor 1 0.293
otx2 orthodenticle homolog 2 0.283
ankrd6 ankyrin repeat domain 6 0.272
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.272
boc brother of CDO 0.270
robo3 roundabout homolog 3 0.269
rag1 recombination activating gene 1 0.268
met met proto-oncogene (hepatocyte growth factor receptor) 0.267
mbnl2 muscleblind-like 2 (Drosophila) 0.248
ascl1a achaete-scute complex-like 1a (Drosophila) 0.246
wnt9a wingless-type MMTV integration site family, member 9A 0.246
wnt8b wingless-type MMTV integration site family, member 8b 0.244
mib mind bomb 0.240
twist1b twist1b 0.230
fn1 fibronectin 1 0.229
crestin crestin 0.228
pcdh8 protocadherin 8 0.224
pou5f1 POU domain, class 5, transcription factor 1 0.224
odc1 ornithine decarboxylase 1 0.217
esrrga estrogen-related receptor gamma a 0.216
smad1 MAD homolog 1 (Drosophila) 0.209
esr2a estrogen receptor 2a 0.208
gbx2 gastrulation brain homeo box 2 0.204
wnt7bb wingless-type MMTV integration site family, member 7Bb 0.202
twist3 twist3 0.202
cyp1a cytochrome P450, family 1, subfamily A 0.200
epha4a eph receptor A4a 0.200
onecutl one cut domain, family member, like 0.199
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.196
ext2 exostoses (multiple) 2 0.196
frzb frizzled-related protein 0.192
aldh1a3 aldehyde dehydrogenase 1 family, member A3 0.190
eya1 eyes absent homolog 1 0.189
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.188
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.184
six4b sine oculis homeobox homolog 4b 0.182
sox10 SRY-box containing gene 10 0.169
psen1 presenilin 1 0.166
gdf6a growth differentiation factor 6a 0.164
pomca proopiomelanocortin a 0.164
ippk inositol 1,3,4,5,6-pentakisphosphate 2-kinase 0.161
gata3 GATA-binding protein 3 0.161
tal1 T-cell acute lymphocytic leukemia 1 0.160
ephb4a eph receptor B4a 0.159
nkx3.2 NK3 homeobox 2 0.156
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.155
ghra growth hormone receptor a 0.152
frmd6 FERM domain containing 6 0.148
cdh5 cadherin 5 0.147
rho rhodopsin 0.147
dlg2 discs, large (Drosophila) homolog 2 0.142
ptk2.1 protein tyrosine kinase 2a 0.141
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.141
igfbp3 insulin-like growth factor binding protein 3 0.137
mef2a myocyte enhancer factor 2a 0.137
fzd8a frizzled homolog 8a 0.137
mpz myelin protein zero 0.135
ihha Indian hedgehog homolog a 0.134
rc3 rabconnectin 3 0.133
sec24c SEC24 family, member C (S. cerevisiae) 0.131
copeb core promoter element binding protein 0.131
atoh1b atonal homolog 1b 0.130
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
GRB2 growth factor receptor-bound protein 2 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.000
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
PLCG1 phospholipase C, gamma 1 1.000
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.000
MAPK14 mitogen-activated protein kinase 14 1.000
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 1.000
MAPK1 mitogen-activated protein kinase 1 1.000
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 1.000
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 1.000
CREBBP CREB binding protein 0.999
INSR insulin receptor 0.999
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.999
IRS1 insulin receptor substrate 1 0.999
ESR1 estrogen receptor 1 0.999
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.999
FGFR1 fibroblast growth factor receptor 1 0.998
IGF1R insulin-like growth factor 1 receptor 0.998
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.997
SH3KBP1 SH3-domain kinase binding protein 1 0.997
GRB10 growth factor receptor-bound protein 10 0.997
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.997
FYN FYN oncogene related to SRC, FGR, YES 0.997
LCK lymphocyte-specific protein tyrosine kinase 0.996
GHR growth hormone receptor 0.996
SOS1 son of sevenless homolog 1 (Drosophila) 0.995
FGFR2 fibroblast growth factor receptor 2 0.995
VAV1 vav 1 guanine nucleotide exchange factor 0.995
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.994
GAB1 GRB2-associated binding protein 1 0.992
LAT linker for activation of T cells 0.991
DNM2 dynamin 2 0.990
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.986
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.986
BCAR1 breast cancer anti-estrogen resistance 1 0.984
GSK3B glycogen synthase kinase 3 beta 0.984
JAK2 Janus kinase 2 0.978
ATF2 activating transcription factor 2 0.978
FGF1 fibroblast growth factor 1 (acidic) 0.976
PTK2 PTK2 protein tyrosine kinase 2 0.973
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.968
NCK1 NCK adaptor protein 1 0.966
MET met proto-oncogene (hepatocyte growth factor receptor) 0.965
DUSP1 dual specificity phosphatase 1 0.962
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.962
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.957
CAV1 caveolin 1, caveolae protein, 22kDa 0.956
PTK2B PTK2B protein tyrosine kinase 2 beta 0.953
SORBS3 sorbin and SH3 domain containing 3 0.946
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.946
EPHA2 EPH receptor A2 0.945
JUN jun proto-oncogene 0.945
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.941
APP amyloid beta (A4) precursor protein 0.940
PTPRJ protein tyrosine phosphatase, receptor type, J 0.937
FHL2 four and a half LIM domains 2 0.935
SH3BP4 SH3-domain binding protein 4 0.931
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.930
TEK TEK tyrosine kinase, endothelial 0.924
IRS2 insulin receptor substrate 2 0.915
SOCS3 suppressor of cytokine signaling 3 0.913
DLG1 discs, large homolog 1 (Drosophila) 0.912
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.912
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.909
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.905
NCK2 NCK adaptor protein 2 0.903
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.901
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.897
AR androgen receptor 0.890
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.885
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.883
VEGFA vascular endothelial growth factor A 0.883
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.880
MUC1 mucin 1, cell surface associated 0.879
STAT1 signal transducer and activator of transcription 1, 91kDa 0.878
MAP2K1 mitogen-activated protein kinase kinase 1 0.877
SH3GL2 SH3-domain GRB2-like 2 0.858
SOCS1 suppressor of cytokine signaling 1 0.856
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.853
VAV2 vav 2 guanine nucleotide exchange factor 0.853
MAPK3 mitogen-activated protein kinase 3 0.832
PDCD6IP programmed cell death 6 interacting protein 0.831
SPRY2 sprouty homolog 2 (Drosophila) 0.829
PECAM1 platelet/endothelial cell adhesion molecule 0.827
CDH5 cadherin 5, type 2 (vascular endothelium) 0.823
C1QA complement component 1, q subcomponent, A chain 0.816
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.811
THBS1 thrombospondin 1 0.801
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.800
PRKCA protein kinase C, alpha 0.787
STAMBP STAM binding protein 0.774
DNM1 dynamin 1 0.773
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Mus musculus
Name Description Probability Func Analog Organism
Egfr epidermal growth factor receptor 1.000
Grb2 growth factor receptor bound protein 2 1.000
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.998
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.998
Efnb2 ephrin B2 0.997
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.996
Cbl Casitas B-lineage lymphoma 0.994
Ephb2 Eph receptor B2 0.993
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.992
Ctnnb1 catenin (cadherin associated protein), beta 1 0.990
Ntf3 neurotrophin 3 0.987
Inpp5d inositol polyphosphate-5-phosphatase D 0.987
Shc1 src homology 2 domain-containing transforming protein C1 0.986
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.982
Nos3 nitric oxide synthase 3, endothelial cell 0.978
Epas1 endothelial PAS domain protein 1 0.977
Vegfa vascular endothelial growth factor A 0.977
Nf1 neurofibromatosis 1 0.974
Gli3 GLI-Kruppel family member GLI3 0.973
Src Rous sarcoma oncogene 0.972
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.970
Notch1 Notch gene homolog 1 (Drosophila) 0.969
Stat3 signal transducer and activator of transcription 3 0.962
Apc adenomatosis polyposis coli 0.961
Ptk2 PTK2 protein tyrosine kinase 2 0.951
Irs1 insulin receptor substrate 1 0.951
Flt4 FMS-like tyrosine kinase 4 0.950
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.948
Plcg1 phospholipase C, gamma 1 0.945
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.944
Fyn Fyn proto-oncogene 0.940
Ret ret proto-oncogene 0.936
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.934
App amyloid beta (A4) precursor protein 0.932
Grb10 growth factor receptor bound protein 10 0.927
Tek endothelial-specific receptor tyrosine kinase 0.924
Psen1 presenilin 1 0.923
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.923
Shh sonic hedgehog 0.921
Insr insulin receptor 0.917
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.915
Phox2a paired-like homeobox 2a 0.908
Smad6 MAD homolog 6 (Drosophila) 0.905
Fzd4 frizzled homolog 4 (Drosophila) 0.903
Lepr leptin receptor 0.896
Jag2 jagged 2 0.886
Ar androgen receptor 0.881
Kdr kinase insert domain protein receptor 0.876
Fshr follicle stimulating hormone receptor 0.875
Gab1 growth factor receptor bound protein 2-associated protein 1 0.874
Foxc1 forkhead box C1 0.869
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.861
Lep leptin 0.859
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.857
Fgfr1 fibroblast growth factor receptor 1 0.852
Tgfa transforming growth factor alpha 0.852
Rxra retinoid X receptor alpha 0.849
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.845
Alx4 aristaless-like homeobox 4 0.844
Hnf4a hepatic nuclear factor 4, alpha 0.833
Shc3 src homology 2 domain-containing transforming protein C3 0.830
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.830
Pax3 paired box gene 3 0.823
Ephb3 Eph receptor B3 0.820
Ptprc protein tyrosine phosphatase, receptor type, C 0.814
Sox10 SRY-box containing gene 10 0.811
Kl klotho 0.809
Jak2 Janus kinase 2 0.806
Dll4 delta-like 4 (Drosophila) 0.803
Lef1 lymphoid enhancer binding factor 1 0.800
Axl AXL receptor tyrosine kinase 0.797
Emx1 empty spiracles homolog 1 (Drosophila) 0.791
Drd2 dopamine receptor D2 0.785
Prkce protein kinase C, epsilon 0.783
Arid5b AT rich interactive domain 5B (MRF1-like) 0.777
Fgfr2 fibroblast growth factor receptor 2 0.777
Il1r1 interleukin 1 receptor, type I 0.776
Kcne1l potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene 0.776
Stat5b signal transducer and activator of transcription 5B 0.774
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.768
Syt7 synaptotagmin VII 0.767
Esr1 estrogen receptor 1 (alpha) 0.767
Csf1r colony stimulating factor 1 receptor 0.763
Cdk5r2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.757
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.756
Smad3 MAD homolog 3 (Drosophila) 0.754
Itih1 inter-alpha trypsin inhibitor, heavy chain 1 0.752
Hoxd13 homeobox D13 0.744
Fzd8 frizzled homolog 8 (Drosophila) 0.743
Tbx3 T-box 3 0.742
Pdgfb platelet derived growth factor, B polypeptide 0.740
Ikzf4 IKAROS family zinc finger 4 0.738
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 0.735
Tiparp TCDD-inducible poly(ADP-ribose) polymerase 0.733
Dlg1 discs, large homolog 1 (Drosophila) 0.728
Ly6h lymphocyte antigen 6 complex, locus H 0.728
Tbx15 T-box 15 0.724
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.724
Epor erythropoietin receptor 0.721
Fgfr4 fibroblast growth factor receptor 4 0.720
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Inpp5d inositol polyphosphate-5-phosphatase D 0.719
Sgk1 serum/glucocorticoid regulated kinase 1 0.661
Sirpa signal-regulatory protein alpha 0.653
Jak1 Janus kinase 1 0.598
Egfr epidermal growth factor receptor 0.539
Stk10 serine/threonine kinase 10 0.524
Jak2 Janus kinase 2 0.523
Fgfr2 fibroblast growth factor receptor 2 0.501
Myh9 myosin, heavy chain 9, non-muscle 0.499
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.419
Acvr1 activin A receptor, type I 0.417
Irs1 insulin receptor substrate 1 0.414
Tmbim6 transmembrane BAX inhibitor motif containing 6 0.409
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.398
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.347
Ptprs protein tyrosine phosphatase, receptor type, S 0.344
Prdm2 PR domain containing 2, with ZNF domain 0.329
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.318
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.301
Grb2 growth factor receptor bound protein 2 0.296
Gria2 glutamate receptor, ionotropic, AMPA 2 0.276
S1pr2 sphingosine-1-phosphate receptor 2 0.275
Grm5 glutamate receptor, metabotropic 5 0.273
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.260
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.240
Gata6 GATA binding protein 6 0.237
RGD1309414 similar to KIAA0913 protein 0.236
Nckap1 NCK-associated protein 1 0.231
Prrx1 paired related homeobox 1 0.221
Sod3 superoxide dismutase 3, extracellular 0.211
Map2 microtubule-associated protein 2 0.209
Itgb1 integrin, beta 1 0.209
Cd44 Cd44 molecule 0.205
Ddr2 discoidin domain receptor tyrosine kinase 2 0.202
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.202
LOC100363783 rCG53773-like 0.199
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.198
Nrxn1 neurexin 1 0.195
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.182
Cfp complement factor properdin 0.181
Ralgds ral guanine nucleotide dissociation stimulator 0.180
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.179
Tecr trans-2,3-enoyl-CoA reductase 0.176
Smad7 SMAD family member 7 0.174
Adra2c adrenergic, alpha-2C-, receptor 0.174
Tgfbr2 transforming growth factor, beta receptor II 0.170
Glg1 golgi apparatus protein 1 0.169
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.167
Klk1l kallikrein 1-like peptidase 0.166
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.165
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.164
Flt1 FMS-related tyrosine kinase 1 0.163
Shox2 short stature homeobox 2 0.157
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.154
Smad1 SMAD family member 1 0.151
Olr287 olfactory receptor 287 0.150
Gjb4 gap junction protein, beta 4 0.144
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.144
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.144
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.139
Rara retinoic acid receptor, alpha 0.138
Pxn paxillin 0.138
Met met proto-oncogene 0.138
RGD1305793 similar to hypothetical protein FLJ20154 0.137
Fgfr1 Fibroblast growth factor receptor 1 0.136
Stat5b signal transducer and activator of transcription 5B 0.136
Nras neuroblastoma ras oncogene 0.132
Itgam integrin, alpha M 0.132
Prkcb protein kinase C, beta 0.131
Fgf18 fibroblast growth factor 18 0.129
Pik3r1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.128
Ube2h ubiquitin-conjugating enzyme E2H 0.128
Map3k3 mitogen activated protein kinase kinase kinase 3 0.124
Itgb5 integrin, beta 5 0.123
Fgf5 fibroblast growth factor 5 0.123
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.122
Ptafr platelet-activating factor receptor 0.121
Bcl2 B-cell CLL/lymphoma 2 0.121
Soat1 sterol O-acyltransferase 1 0.120
Agtr1a angiotensin II receptor, type 1a 0.120
Enpep glutamyl aminopeptidase 0.119
Eef2 eukaryotic translation elongation factor 2 0.119
Stx6 syntaxin 6 0.119
Madcam1 mucosal vascular addressin cell adhesion molecule 1 0.118
Ednra endothelin receptor type A 0.117
Ptk2b PTK2B protein tyrosine kinase 2 beta 0.117
Hk1 hexokinase 1 0.117
Cadm1 cell adhesion molecule 1 0.116
Mprip myosin phosphatase Rho interacting protein 0.116
Ncan neurocan 0.116
Sstr5 somatostatin receptor 5 0.115
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.114
Tpc1808 tropic 1808 0.112
Lnpep leucyl/cystinyl aminopeptidase 0.112
Lphn2 latrophilin 2 0.111
Creb1 cAMP responsive element binding protein 1 0.110
Grip1 glutamate receptor interacting protein 1 0.109
P2ry2 purinergic receptor P2Y, G-protein coupled, 2 0.108
Foxs1 forkhead box S1 0.106
Map1a microtubule-associated protein 1A 0.106
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism