IMP
Process View
The network for 'canonical wnt signaling pathway involved in osteoblast differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
canonical wnt signaling pathway involved in osteoblast differentiation
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BBS10 | Bardet-Biedl syndrome 10 | 0.999 | |
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.993 | |
| FGF18 | fibroblast growth factor 18 | 0.962 | |
| SFRP1 | secreted frizzled-related protein 1 | 0.957 | |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.919 | |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.911 | |
| FOXF2 | forkhead box F2 | 0.893 | |
| MXRA5 | matrix-remodelling associated 5 | 0.881 | |
| NDP | Norrie disease (pseudoglioma) | 0.846 | |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.826 | |
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.813 | |
| IHH | Indian hedgehog | 0.609 | |
| WIF1 | WNT inhibitory factor 1 | 0.590 | |
| WNT10A | wingless-type MMTV integration site family, member 10A | 0.516 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.493 | |
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.366 | |
| THBS2 | thrombospondin 2 | 0.341 | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.337 | |
| MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.337 | |
| BMP4 | bone morphogenetic protein 4 | 0.324 | |
| FZD8 | frizzled homolog 8 (Drosophila) | 0.308 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.306 | |
| EHF | ets homologous factor | 0.301 | |
| FGF3 | fibroblast growth factor 3 | 0.282 | |
| AQP5 | aquaporin 5 | 0.249 | |
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.239 | |
| FGF4 | fibroblast growth factor 4 | 0.236 | |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.235 | |
| WNT11 | wingless-type MMTV integration site family, member 11 | 0.219 | |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.216 | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.191 | |
| RGS2 | regulator of G-protein signaling 2, 24kDa | 0.186 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.177 | |
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.170 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.165 | |
| SMAD1 | SMAD family member 1 | 0.164 | |
| COL10A1 | collagen, type X, alpha 1 | 0.159 | |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.155 | |
| PRRX1 | paired related homeobox 1 | 0.149 | |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.147 | |
| COL4A6 | collagen, type IV, alpha 6 | 0.133 | |
| BMP7 | bone morphogenetic protein 7 | 0.129 | |
| FOXF1 | forkhead box F1 | 0.120 | |
| PKP1 | plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) | 0.119 | |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.108 | |
| POU3F1 | POU class 3 homeobox 1 | 0.105 | |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.105 | |
| COL14A1 | collagen, type XIV, alpha 1 | 0.104 | |
| GDF10 | growth differentiation factor 10 | 0.102 | |
| EPHB3 | EPH receptor B3 | 0.102 | |
| LBX1 | ladybird homeobox 1 | 0.101 | |
| SFRP2 | secreted frizzled-related protein 2 | 0.100 | |
| SIX2 | SIX homeobox 2 | 0.099 | |
| FOXD3 | forkhead box D3 | 0.098 | |
| GAS1 | growth arrest-specific 1 | 0.097 | |
| INHBB | inhibin, beta B | 0.094 | |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.093 | |
| GPR124 | G protein-coupled receptor 124 | 0.093 | |
| C1QL1 | complement component 1, q subcomponent-like 1 | 0.092 | |
| HOXD13 | homeobox D13 | 0.092 | |
| VEGFC | vascular endothelial growth factor C | 0.092 | |
| OGN | osteoglycin | 0.091 | |
| COL5A1 | collagen, type V, alpha 1 | 0.090 | |
| OMD | osteomodulin | 0.089 | |
| FOXE1 | forkhead box E1 (thyroid transcription factor 2) | 0.087 | |
| BMP8A | bone morphogenetic protein 8a | 0.086 | |
| WNT6 | wingless-type MMTV integration site family, member 6 | 0.085 | |
| NPAS1 | neuronal PAS domain protein 1 | 0.084 | |
| HMX1 | H6 family homeobox 1 | 0.082 | |
| EGFL6 | EGF-like-domain, multiple 6 | 0.082 | |
| P2RX2 | purinergic receptor P2X, ligand-gated ion channel, 2 | 0.082 | |
| TLX3 | T-cell leukemia homeobox 3 | 0.081 | |
| RAX | retina and anterior neural fold homeobox | 0.080 | |
| TWIST1 | twist homolog 1 (Drosophila) | 0.080 | |
| PRRX2 | paired related homeobox 2 | 0.080 | |
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 | 0.080 | |
| HS3ST6 | heparan sulfate (glucosamine) 3-O-sulfotransferase 6 | 0.079 | |
| FOXB1 | forkhead box B1 | 0.078 | |
| MNX1 | motor neuron and pancreas homeobox 1 | 0.078 | |
| NKX3-2 | NK3 homeobox 2 | 0.076 | |
| WNT7A | wingless-type MMTV integration site family, member 7A | 0.073 | |
| HOXC8 | homeobox C8 | 0.073 | |
| NEUROG2 | neurogenin 2 | 0.073 | |
| COL2A1 | collagen, type II, alpha 1 | 0.073 | |
| WNT4 | wingless-type MMTV integration site family, member 4 | 0.070 | |
| SHH | sonic hedgehog | 0.070 | |
| FBLN1 | fibulin 1 | 0.069 | |
| GDNF | glial cell derived neurotrophic factor | 0.069 | |
| DLX4 | distal-less homeobox 4 | 0.068 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.066 | |
| EPHB2 | EPH receptor B2 | 0.066 | |
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.066 | |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | 0.066 | |
| LRRC17 | leucine rich repeat containing 17 | 0.065 | |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 | 0.064 | |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 | 0.064 | |
| HOXD10 | homeobox D10 | 0.064 | |
| OLFML1 | olfactomedin-like 1 | 0.062 | |
| HOXD11 | homeobox D11 | 0.062 | |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.062 |
