The network for 'calcium ion transport from endoplasmic reticulum to cytosol' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

calcium ion transport from endoplasmic reticulum to cytosol

The directed movement of calcium ion from endoplasmic reticulum to cytosol.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 0.996
GSTM1 glutathione S-transferase mu 1 0.986
GSTM2 glutathione S-transferase mu 2 (muscle) 0.968
CCL5 chemokine (C-C motif) ligand 5 0.945
CXCL9 chemokine (C-X-C motif) ligand 9 0.457
CCL22 chemokine (C-C motif) ligand 22 0.425
CCR7 chemokine (C-C motif) receptor 7 0.419
CCL4 chemokine (C-C motif) ligand 4 0.374
CCL3 chemokine (C-C motif) ligand 3 0.291
KIAA1683 KIAA1683 0.291
CCR4 chemokine (C-C motif) receptor 4 0.241
GSTM4 glutathione S-transferase mu 4 0.231
IL2RB interleukin 2 receptor, beta 0.195
IFNG interferon, gamma 0.152
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.145
DTNA dystrobrevin, alpha 0.124
SYNM synemin, intermediate filament protein 0.110
CCL7 chemokine (C-C motif) ligand 7 0.107
ACVR1B activin A receptor, type IB 0.107
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.084
CCL19 chemokine (C-C motif) ligand 19 0.077
CXCL13 chemokine (C-X-C motif) ligand 13 0.075
AKAP6 A kinase (PRKA) anchor protein 6 0.066
CCR1 chemokine (C-C motif) receptor 1 0.063
CCL8 chemokine (C-C motif) ligand 8 0.061
CCL13 chemokine (C-C motif) ligand 13 0.058
CCL2 chemokine (C-C motif) ligand 2 0.056
CCR2 chemokine (C-C motif) receptor 2 0.044
IL16 interleukin 16 (lymphocyte chemoattractant factor) 0.043
IL1B interleukin 1, beta 0.040
IDE insulin-degrading enzyme 0.040
IL10 interleukin 10 0.039
CD40LG CD40 ligand 0.037
MYO10 myosin X 0.034
EHD1 EH-domain containing 1 0.034
IRF4 interferon regulatory factor 4 0.033
TGFBR1 transforming growth factor, beta receptor 1 0.030
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.030
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.030
CCR6 chemokine (C-C motif) receptor 6 0.029
CXCR6 chemokine (C-X-C motif) receptor 6 0.029
IL2RG interleukin 2 receptor, gamma 0.028
SPTA1 spectrin, alpha, erythrocytic 1 (elliptocytosis 2) 0.025
IL21R interleukin 21 receptor 0.025
ARRB2 arrestin, beta 2 0.024
CXCR3 chemokine (C-X-C motif) receptor 3 0.023
IL8 interleukin 8 0.023
GSTM3 glutathione S-transferase mu 3 (brain) 0.022
RGS1 regulator of G-protein signaling 1 0.020
DARC Duffy blood group, chemokine receptor 0.019
SLAMF7 SLAM family member 7 0.019
CCL21 chemokine (C-C motif) ligand 21 0.018
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.018
DTNB dystrobrevin, beta 0.018
DPP4 dipeptidyl-peptidase 4 0.015
ARRB1 arrestin, beta 1 0.015
CCL11 chemokine (C-C motif) ligand 11 0.015
IL18RAP interleukin 18 receptor accessory protein 0.015
ARF3 ADP-ribosylation factor 3 0.014
CD2 CD2 molecule 0.014
ADAMDEC1 ADAM-like, decysin 1 0.013
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.013
CFL1 cofilin 1 (non-muscle) 0.013
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.012
TNF tumor necrosis factor 0.012
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.012
CCL23 chemokine (C-C motif) ligand 23 0.012
IL1R2 interleukin 1 receptor, type II 0.012
IL10RA interleukin 10 receptor, alpha 0.012
SIT1 signaling threshold regulating transmembrane adaptor 1 0.012
CCR9 chemokine (C-C motif) receptor 9 0.012
CD48 CD48 molecule 0.011
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.011
SPTB spectrin, beta, erythrocytic 0.011
EBI3 Epstein-Barr virus induced 3 0.011
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.011
TRAPPC1 trafficking protein particle complex 1 0.011
IL4 interleukin 4 0.011
CLEC10A C-type lectin domain family 10, member A 0.011
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.011
IL7R interleukin 7 receptor 0.011
RHAG Rh-associated glycoprotein 0.010
CXCR5 chemokine (C-X-C motif) receptor 5 0.010
IL1F5 interleukin 1 family, member 5 (delta) 0.010
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.010
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.912
Sgcg sarcoglycan, gamma (dystrophin-associated glycoprotein) 0.808
Ldb3 LIM domain binding 3 0.788
Ryr2 ryanodine receptor 2, cardiac 0.760
Ccr1 chemokine (C-C motif) receptor 1 0.634
Casq2 calsequestrin 2 0.623
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.597
Hbb-b1 hemoglobin, beta adult major chain 0.562
Myom2 myomesin 2 0.548
Cav3 caveolin 3 0.531
Spna1 spectrin alpha 1 0.490
Spnb1 spectrin beta 1 0.406
Actn2 actinin alpha 2 0.406
Pvalb parvalbumin 0.374
Myl1 myosin, light polypeptide 1 0.321
Srpk3 serine/arginine-rich protein specific kinase 3 0.305
Dtna dystrobrevin alpha 0.274
Ckmt2 creatine kinase, mitochondrial 2 0.258
Ckm creatine kinase, muscle 0.245
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.238
Sh3bgr SH3-binding domain glutamic acid-rich protein 0.192
Ttn titin 0.187
Cox6a2 cytochrome c oxidase, subunit VI a, polypeptide 2 0.186
Phkg1 phosphorylase kinase gamma 1 0.172
Hrc histidine rich calcium binding protein 0.158
Ccr2 chemokine (C-C motif) receptor 2 0.157
Lmod3 leiomodin 3 (fetal) 0.151
Alpk3 alpha-kinase 3 0.151
Scn1a sodium channel, voltage-gated, type I, alpha 0.148
Tcap titin-cap 0.146
Smyd1 SET and MYND domain containing 1 0.140
Cox8b cytochrome c oxidase, subunit VIIIb 0.125
Ccl2 chemokine (C-C motif) ligand 2 0.120
Yipf7 Yip1 domain family, member 7 0.118
Myoz2 myozenin 2 0.107
Actc1 actin, alpha, cardiac muscle 1 0.105
Dag1 dystroglycan 1 0.103
Hspb7 heat shock protein family, member 7 (cardiovascular) 0.101
Myom1 myomesin 1 0.095
Nckap1l NCK associated protein 1 like 0.087
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 0.087
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult 0.085
Pgam2 phosphoglycerate mutase 2 0.081
Myl3 myosin, light polypeptide 3 0.070
Ptpro protein tyrosine phosphatase, receptor type, O 0.068
Txlnb taxilin beta 0.062
Cmya5 cardiomyopathy associated 5 0.062
Fktn fukutin 0.058
Lmod2 leiomodin 2 (cardiac) 0.057
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.056
Itgb1bp2 integrin beta 1 binding protein 2 0.053
Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.047
Frmd5 FERM domain containing 5 0.046
Usp13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.046
Pygm muscle glycogen phosphorylase 0.046
Art1 ADP-ribosyltransferase 1 0.046
6330503K22Rik RIKEN cDNA 6330503K22 gene 0.045
Casq1 calsequestrin 1 0.045
Smpx small muscle protein, X-linked 0.045
Sln sarcolipin 0.045
Kcna7 potassium voltage-gated channel, shaker-related subfamily, member 7 0.042
Gja1 gap junction protein, alpha 1 0.037
Coro6 coronin 6 0.036
Art3 ADP-ribosyltransferase 3 0.036
Lrrc2 leucine rich repeat containing 2 0.036
Apobec2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2 0.036
Asb11 ankyrin repeat and SOCS box-containing 11 0.035
Rbm24 RNA binding motif protein 24 0.035
Gnao1 guanine nucleotide binding protein, alpha O 0.035
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.035
2310046A06Rik RIKEN cDNA 2310046A06 gene 0.034
Popdc3 popeye domain containing 3 0.032
Prkcc protein kinase C, gamma 0.032
Csrp3 cysteine and glycine-rich protein 3 0.032
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.031
Kitl kit ligand 0.030
Mstn myostatin 0.028
Calm1 calmodulin 1 0.027
Rpl3l ribosomal protein L3-like 0.027
Esrrg estrogen-related receptor gamma 0.027
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.026
Pbx1 pre B-cell leukemia transcription factor 1 0.026
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.026
Klhl24 kelch-like 24 (Drosophila) 0.026
Tuba8 tubulin, alpha 8 0.025
Tnnt2 troponin T2, cardiac 0.025
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.025
Eef1a2 eukaryotic translation elongation factor 1 alpha 2 0.025
Etl4 enhancer trap locus 4 0.025
Xirp1 xin actin-binding repeat containing 1 0.024
Sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.024
Rgs6 regulator of G-protein signaling 6 0.024
Sgcb sarcoglycan, beta (dystrophin-associated glycoprotein) 0.024
En2 engrailed 2 0.023
Fkrp fukutin related protein 0.022
Tnnt3 troponin T3, skeletal, fast 0.022
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.021
Popdc2 popeye domain containing 2 0.021
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.021
Uros uroporphyrinogen III synthase 0.021
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Rattus norvegicus
Name Description Probability Func Analog Organism
Asph aspartate-beta-hydroxylase 0.715
Nexn nexilin (F actin binding protein) 0.258
Unc45b unc-45 homolog B (C. elegans) 0.196
Pgam2 phosphoglycerate mutase 2 (muscle) 0.183
Ldb3 LIM domain binding 3 0.146
Myl1 myosin, light chain 1 0.135
Casq2 calsequestrin 2 (cardiac muscle) 0.132
Pygm phosphorylase, glycogen, muscle 0.126
Dhrs7c dehydrogenase/reductase (SDR family) member 7C 0.118
Pkia protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.118
Ckm creatine kinase, muscle 0.116
Fitm1 fat storage-inducing transmembrane protein 1 0.107
Lrrc39 leucine rich repeat containing 39 0.077
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.075
Inpp4b inositol polyphosphate-4-phosphatase, type II 0.072
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.072
Ttn titin 0.071
Ampd1 adenosine monophosphate deaminase 1 (isoform M) 0.066
Apobec2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.065
Actc1 actin, alpha, cardiac muscle 1 0.063
Mybpc1 myosin binding protein C, slow type 0.062
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.061
Phka1 phosphorylase kinase, alpha 1 0.061
Sspn sarcospan 0.060
Ccl4 chemokine (C-C motif) ligand 4 0.058
Ky kyphoscoliosis peptidase 0.056
Cav3 caveolin 3 0.053
Asb12 ankyrin repeat and SOCS box-containing 12 0.053
Cdon Cdon homolog (mouse) 0.052
Art1 ADP-ribosyltransferase 1 0.049
Ndufc1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 0.046
Tnnc2 troponin C type 2 (fast) 0.045
Tnni3k TNNI3 interacting kinase 0.044
Hrc histidine rich calcium binding protein 0.043
Myo9a myosin IXA 0.043
Smpx small muscle protein, X-linked 0.042
Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.039
Ndufs4 NADH dehydrogenase (ubiquinone) Fe-S protein 4 0.039
Rpl3l ribosomal protein L3-like 0.038
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.036
Tnni1 troponin I type 1 (skeletal, slow) 0.034
Tnnt3 troponin T type 3 (skeletal, fast) 0.034
P2ry1 purinergic receptor P2Y, G-protein coupled, 1 0.033
Rasa2 RAS p21 protein activator 2 0.033
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.032
Obscn obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.032
A2bp1 ataxin 2 binding protein 1 0.031
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.030
Cacng1 calcium channel, voltage-dependent, gamma subunit 1 0.030
Scn4b sodium channel, voltage-gated, type IV, beta 0.030
Fgf16 fibroblast growth factor 16 0.030
Gstm1 glutathione S-transferase mu 1 0.029
Hcrtr2 hypocretin (orexin) receptor 2 0.029
Ckmt2 creatine kinase, mitochondrial 2, sarcomeric 0.029
Utrn utrophin 0.028
Myh2 myosin, heavy chain 2, skeletal muscle, adult 0.027
Capn6 calpain 6 0.027
Plp1 proteolipid protein 1 0.026
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.026
Mylpf myosin light chain, phosphorylatable, fast skeletal muscle 0.026
Slc26a2 solute carrier family 26 (sulfate transporter), member 2 0.026
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.026
Abcd2 ATP-binding cassette, subfamily D (ALD), member 2 0.026
Myoc myocilin 0.025
Tmod4 tropomodulin 4 0.025
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.025
Neb nebulin 0.025
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult 0.025
Sele selectin E 0.024
Selp selectin P 0.024
Tgfb2 transforming growth factor, beta 2 0.024
Sptbn1 spectrin, beta, non-erythrocytic 1 0.024
Rgs1 regulator of G-protein signaling 1 0.024
Nrxn1 neurexin 1 0.024
Cd83 CD83 molecule 0.023
Trim72 tripartite motif-containing 72 0.023
LOC681849 similar to Protein C6orf142 homolog 0.023
Rhag Rh-associated glycoprotein 0.023
Stc1 stanniocalcin 1 0.022
Adrbk2 adrenergic, beta, receptor kinase 2 0.021
Colec12 collectin sub-family member 12 0.021
Tmem38a transmembrane protein 38a 0.021
Inhba inhibin beta-A 0.021
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.021
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.021
Chrm2 cholinergic receptor, muscarinic 2 0.020
Myf6 myogenic factor 6 0.020
Ctsk cathepsin K 0.020
Sparcl1 SPARC-like 1 (hevin) 0.020
Klra5 killer cell lectin-like receptor, subfamily A, member 5 0.020
Fgf13 fibroblast growth factor 13 0.020
Lama2 laminin, alpha 2 0.020
Lims1 LIM and senescent cell antigen-like domains 1 0.019
Mmp8 matrix metallopeptidase 8 0.019
Kcnd2 potassium voltage-gated channel, Shal-related subfamily, member 2 0.019
Sv2b synaptic vesicle glycoprotein 2b 0.018
Atxn3 ataxin 3 0.018
Cox8b cytochrome c oxidase, subunit VIIIb 0.018
Manea mannosidase, endo-alpha 0.018
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.018
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism