IMP
Process View
The network for 'response to interferon alpha' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
response to interferon alpha
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.994 | |
| IFI44L | interferon-induced protein 44-like | 0.985 | |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.915 | |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.911 | |
| IFI44 | interferon-induced protein 44 | 0.874 | |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.867 | |
| IRF9 | interferon regulatory factor 9 | 0.825 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.778 | |
| MX2 | myxovirus (influenza virus) resistance 2 (mouse) | 0.777 | |
| ISG15 | ISG15 ubiquitin-like modifier | 0.609 | |
| MX1 | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 0.603 | |
| SP110 | SP110 nuclear body protein | 0.597 | |
| OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 0.564 | |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.554 | |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.395 | |
| IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.365 | |
| AXL | AXL receptor tyrosine kinase | 0.340 | |
| GAS6 | growth arrest-specific 6 | 0.320 | |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.294 | |
| HERC5 | hect domain and RLD 5 | 0.266 | |
| BST2 | bone marrow stromal cell antigen 2 | 0.251 | |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.251 | |
| IFITM1 | interferon induced transmembrane protein 1 (9-27) | 0.231 | |
| IFI6 | interferon, alpha-inducible protein 6 | 0.204 | |
| PLSCR1 | phospholipid scramblase 1 | 0.153 | |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.134 | |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.132 | |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.131 | |
| IRF7 | interferon regulatory factor 7 | 0.123 | |
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.080 | |
| IFI27 | interferon, alpha-inducible protein 27 | 0.072 | |
| JAK1 | Janus kinase 1 | 0.066 | |
| USP18 | ubiquitin specific peptidase 18 | 0.061 | |
| SP100 | SP100 nuclear antigen | 0.056 | |
| TRIM21 | tripartite motif containing 21 | 0.056 | |
| XAF1 | XIAP associated factor 1 | 0.054 | |
| IFI35 | interferon-induced protein 35 | 0.051 | |
| TRIM14 | tripartite motif containing 14 | 0.042 | |
| MOV10 | Mov10, Moloney leukemia virus 10, homolog (mouse) | 0.036 | |
| PML | promyelocytic leukemia | 0.030 | |
| DHX58 | DEXH (Asp-Glu-X-His) box polypeptide 58 | 0.029 | |
| SAMD9 | sterile alpha motif domain containing 9 | 0.027 | |
| CMPK2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.026 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.020 | |
| TRIM22 | tripartite motif containing 22 | 0.019 | |
| PLXNB1 | plexin B1 | 0.018 | |
| KLF13 | Kruppel-like factor 13 | 0.016 | |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.013 | |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.013 | |
| TFG | TRK-fused gene | 0.012 | |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.012 | |
| DICER1 | dicer 1, ribonuclease type III | 0.012 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.012 | |
| RUNX1 | runt-related transcription factor 1 | 0.011 | |
| NMI | N-myc (and STAT) interactor | 0.011 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Stat1 | signal transducer and activator of transcription 1 | 0.833 | |
| Irf9 | interferon regulatory factor 9 | 0.781 | |
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.642 | |
| Irgm1 | immunity-related GTPase family M member 1 | 0.517 | |
| Mndal | myeloid nuclear differentiation antigen like | 0.463 | |
| Rtp4 | receptor transporter protein 4 | 0.436 | |
| Igtp | interferon gamma induced GTPase | 0.420 | |
| Isg15 | ISG15 ubiquitin-like modifier | 0.322 | |
| Ifih1 | interferon induced with helicase C domain 1 | 0.285 | |
| Trim30a | tripartite motif-containing 30A | 0.255 | |
| Ifi47 | interferon gamma inducible protein 47 | 0.234 | |
| Ifi203 | interferon activated gene 203 | 0.196 | |
| Usp18 | ubiquitin specific peptidase 18 | 0.196 | |
| Gbp7 | guanylate binding protein 7 | 0.170 | |
| Gbp3 | guanylate binding protein 3 | 0.148 | |
| Oasl2 | 2'-5' oligoadenylate synthetase-like 2 | 0.138 | |
| Iigp1 | interferon inducible GTPase 1 | 0.133 | |
| Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.124 | |
| Gbp2 | guanylate binding protein 2 | 0.108 | |
| Mnda | myeloid cell nuclear differentiation antigen | 0.082 | |
| Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.072 | |
| Sp100 | nuclear antigen Sp100 | 0.054 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.047 | |
| Tyro3 | TYRO3 protein tyrosine kinase 3 | 0.047 | |
| Ifi44 | interferon-induced protein 44 | 0.044 | |
| Dtx3l | deltex 3-like (Drosophila) | 0.042 | |
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.035 | |
| Ddx58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.030 | |
| Irgm2 | immunity-related GTPase family M member 2 | 0.030 | |
| Parp12 | poly (ADP-ribose) polymerase family, member 12 | 0.029 | |
| Lgals9 | lectin, galactose binding, soluble 9 | 0.028 | |
| Ly6a | lymphocyte antigen 6 complex, locus A | 0.028 | |
| Cmpk2 | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | 0.024 | |
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.023 | |
| Ifi27l2a | interferon, alpha-inducible protein 27 like 2A | 0.022 | |
| D14Ertd668e | DNA segment, Chr 14, ERATO Doi 668, expressed | 0.020 | |
| Trim30d | tripartite motif-containing 30D | 0.020 | |
| Nmi | N-myc (and STAT) interactor | 0.020 | |
| Samd9l | sterile alpha motif domain containing 9-like | 0.019 | |
| Irf7 | interferon regulatory factor 7 | 0.018 | |
| Ifi35 | interferon-induced protein 35 | 0.018 | |
| AI607873 | expressed sequence AI607873 | 0.017 | |
| Ms4a4c | membrane-spanning 4-domains, subfamily A, member 4C | 0.017 | |
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.015 | |
| Tor3a | torsin family 3, member A | 0.015 | |
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.015 | |
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.014 | |
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.014 | |
| Trim21 | tripartite motif-containing 21 | 0.014 | |
| Ifitm3 | interferon induced transmembrane protein 3 | 0.013 | |
| Ifi204 | interferon activated gene 204 | 0.013 | |
| Gvin1 | GTPase, very large interferon inducible 1 | 0.012 | |
| Herc6 | hect domain and RLD 6 | 0.012 | |
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.012 | |
| Ddx60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.012 | |
| Bst2 | bone marrow stromal cell antigen 2 | 0.012 |
Loading network...
Rattus norvegicus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ifitm3 | interferon induced transmembrane protein 3 | 0.971 | |
| S100a11 | S100 calcium binding protein A11 (calizzarin) | 0.328 | |
| C1r | complement component 1, r subcomponent | 0.227 | |
| Ifitm1 | interferon induced transmembrane protein 1 | 0.190 | |
| Mgp | matrix Gla protein | 0.154 | |
| Ifitm2 | interferon induced transmembrane protein 2 | 0.138 | |
| Serping1 | serine (or cysteine) peptidase inhibitor, clade G, member 1 | 0.081 | |
| Timp1 | TIMP metallopeptidase inhibitor 1 | 0.056 | |
| Tagln2 | transgelin 2 | 0.055 | |
| S100a6 | S100 calcium binding protein A6 | 0.051 | |
| Lgals3bp | lectin, galactoside-binding, soluble, 3 binding protein | 0.040 | |
| Ifit3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.028 | |
| C1s | complement component 1, s subcomponent | 0.024 | |
| Lgals3 | lectin, galactoside-binding, soluble, 3 | 0.022 | |
| Lgals1 | lectin, galactoside-binding, soluble, 1 | 0.017 | |
| Anxa5 | annexin A5 | 0.016 | |
| Pla1a | phospholipase A1 member A | 0.014 | |
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.014 | |
| Oasl | 2'-5'-oligoadenylate synthetase-like | 0.012 | |
| Tmem176b | transmembrane protein 176B | 0.011 | |
| Crip | cysteine-rich intestinal protein | 0.011 | |
| S100a10 | S100 calcium binding protein A10 | 0.010 | |
| Psmb8 | proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) | 0.010 |