IMP
Process View
The network for 'negative regulation of type b pancreatic cell apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of type b pancreatic cell apoptotic process
Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.999 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.637 | |
| PSEN1 | presenilin 1 | 0.382 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.358 | |
| TCF4 | transcription factor 4 | 0.176 | |
| GLIS2 | GLIS family zinc finger 2 | 0.148 | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.144 | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.100 | |
| APC | adenomatous polyposis coli | 0.067 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.062 | |
| EMD | emerin | 0.061 | |
| HIC1 | hypermethylated in cancer 1 | 0.058 | |
| BTRC | beta-transducin repeat containing | 0.049 | |
| JUP | junction plakoglobin | 0.047 | |
| CAPN2 | calpain 2, (m/II) large subunit | 0.044 | |
| AR | androgen receptor | 0.035 | |
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.032 | |
| CREBBP | CREB binding protein | 0.031 | |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.028 | |
| TNIK | TRAF2 and NCK interacting kinase | 0.023 | |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.022 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.021 | |
| S100A10 | S100 calcium binding protein A10 | 0.019 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.015 | |
| FERMT2 | fermitin family member 2 | 0.013 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pax6 | paired box gene 6 | 0.997 | |
| Prrx1 | paired related homeobox 1 | 0.994 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.992 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.977 | |
| Neurog2 | neurogenin 2 | 0.965 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.896 | |
| Neurod1 | neurogenic differentiation 1 | 0.863 | |
| Shh | sonic hedgehog | 0.833 | |
| Onecut1 | one cut domain, family member 1 | 0.814 | |
| Insm1 | insulinoma-associated 1 | 0.761 | |
| Neurod4 | neurogenic differentiation 4 | 0.673 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.648 | |
| Gata4 | GATA binding protein 4 | 0.568 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.526 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.525 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.524 | |
| Dlx6 | distal-less homeobox 6 | 0.510 | |
| En1 | engrailed 1 | 0.498 | |
| Mecom | MDS1 and EVI1 complex locus | 0.441 | |
| Msx1 | homeobox, msh-like 1 | 0.432 | |
| Gata1 | GATA binding protein 1 | 0.397 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.356 | |
| Nkx3-2 | NK3 homeobox 2 | 0.356 | |
| Nhlh1 | nescient helix loop helix 1 | 0.343 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.338 | |
| Gsc | goosecoid homeobox | 0.334 | |
| Lhx5 | LIM homeobox protein 5 | 0.329 | |
| Pax3 | paired box gene 3 | 0.308 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.302 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.295 | |
| Hoxd13 | homeobox D13 | 0.292 | |
| Nkx6-1 | NK6 homeobox 1 | 0.274 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.266 | |
| Hic1 | hypermethylated in cancer 1 | 0.242 | |
| Srrm4 | serine/arginine repetitive matrix 4 | 0.241 | |
| Foxd2 | forkhead box D2 | 0.238 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.238 | |
| Foxc2 | forkhead box C2 | 0.234 | |
| Dlx1 | distal-less homeobox 1 | 0.233 | |
| Tcf3 | transcription factor 3 | 0.224 | |
| Alx3 | aristaless-like homeobox 3 | 0.210 | |
| Sox11 | SRY-box containing gene 11 | 0.207 | |
| Col22a1 | collagen, type XXII, alpha 1 | 0.207 | |
| Lhx3 | LIM homeobox protein 3 | 0.203 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.192 | |
| Six3 | sine oculis-related homeobox 3 homolog (Drosophila) | 0.190 | |
| Sox9 | SRY-box containing gene 9 | 0.184 | |
| Nkx2-2 | NK2 transcription factor related, locus 2 (Drosophila) | 0.180 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.176 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.162 | |
| Lep | leptin | 0.160 | |
| Neurog3 | neurogenin 3 | 0.149 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.148 | |
| Prph2 | peripherin 2 | 0.147 | |
| Shox2 | short stature homeobox 2 | 0.147 | |
| Lhx9 | LIM homeobox protein 9 | 0.142 | |
| Prox1 | prospero-related homeobox 1 | 0.139 | |
| Pou4f2 | POU domain, class 4, transcription factor 2 | 0.137 | |
| Fgf8 | fibroblast growth factor 8 | 0.136 | |
| Efna2 | ephrin A2 | 0.135 | |
| Tal2 | T-cell acute lymphocytic leukemia 2 | 0.133 | |
| Ebf3 | early B-cell factor 3 | 0.132 | |
| Cbfa2t3 | core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) | 0.131 | |
| Zic1 | zinc finger protein of the cerebellum 1 | 0.126 | |
| Dlx2 | distal-less homeobox 2 | 0.125 | |
| Pde6b | phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide | 0.115 | |
| Runx2 | runt related transcription factor 2 | 0.112 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.101 | |
| Runx1t1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.101 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.101 | |
| Ebf2 | early B-cell factor 2 | 0.100 | |
| Cdx2 | caudal type homeobox 2 | 0.099 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.099 | |
| Prph | peripherin | 0.097 | |
| Sim2 | single-minded homolog 2 (Drosophila) | 0.095 | |
| Evx1 | even skipped homeotic gene 1 homolog | 0.093 | |
| Lmo2 | LIM domain only 2 | 0.092 | |
| Neurog1 | neurogenin 1 | 0.090 | |
| Atoh7 | atonal homolog 7 (Drosophila) | 0.088 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.085 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.085 | |
| Nkx1-2 | NK1 transcription factor related, locus 2 (Drosophila) | 0.084 | |
| Hoxd1 | homeobox D1 | 0.083 | |
| T | brachyury | 0.078 | |
| Bmp2 | bone morphogenetic protein 2 | 0.076 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.075 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.073 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.073 | |
| Pou3f2 | POU domain, class 3, transcription factor 2 | 0.071 | |
| Hoxb1 | homeobox B1 | 0.071 | |
| Prrx2 | paired related homeobox 2 | 0.071 | |
| En2 | engrailed 2 | 0.071 | |
| Foxd4 | forkhead box D4 | 0.070 | |
| Myf5 | myogenic factor 5 | 0.069 | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.068 | |
| Fgf17 | fibroblast growth factor 17 | 0.066 | |
| Kcnj11 | potassium inwardly rectifying channel, subfamily J, member 11 | 0.065 | |
| Smo | smoothened homolog (Drosophila) | 0.065 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.065 | |
| Pax9 | paired box gene 9 | 0.064 |