The network for 'cellular response to cadmium ion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to cadmium ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.

Mus musculus
Name Description Probability Func Analog Organism
Atf2 activating transcription factor 2 0.986
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.948
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.925
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.912
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.908
Cps1 carbamoyl-phosphate synthetase 1 0.885
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.884
Mapk1 mitogen-activated protein kinase 1 0.857
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.833
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.830
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.800
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.787
Hrg histidine-rich glycoprotein 0.752
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.675
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 0.668
Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 0.664
Mup5 major urinary protein 5 0.660
Slc22a18 solute carrier family 22 (organic cation transporter), member 18 0.599
Aadac arylacetamide deacetylase (esterase) 0.585
Akr1c6 aldo-keto reductase family 1, member C6 0.564
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.562
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.548
Nsfl1c NSFL1 (p97) cofactor (p47) 0.539
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.520
F9 coagulation factor IX 0.509
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.502
Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 0.492
Inmt indolethylamine N-methyltransferase 0.483
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 0.453
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.435
Fmo3 flavin containing monooxygenase 3 0.434
G6pc glucose-6-phosphatase, catalytic 0.433
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 0.416
Prkce protein kinase C, epsilon 0.412
Hamp hepcidin antimicrobial peptide 0.397
Apoc4 apolipoprotein C-IV 0.391
Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 0.390
Nr1i3 nuclear receptor subfamily 1, group I, member 3 0.387
Afm afamin 0.376
Tdo2 tryptophan 2,3-dioxygenase 0.361
Cml2 camello-like 2 0.361
Tat tyrosine aminotransferase 0.352
Pon1 paraoxonase 1 0.346
Azgp1 alpha-2-glycoprotein 1, zinc 0.343
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.336
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.330
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.322
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.322
Mat1a methionine adenosyltransferase I, alpha 0.320
Sult1d1 sulfotransferase family 1D, member 1 0.315
Crp C-reactive protein, pentraxin-related 0.313
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.302
Akr1d1 aldo-keto reductase family 1, member D1 0.297
Otc ornithine transcarbamylase 0.296
F13b coagulation factor XIII, beta subunit 0.280
Alb albumin 0.275
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.267
Upp2 uridine phosphorylase 2 0.254
Ces3a carboxylesterase 3A 0.246
Pigr polymeric immunoglobulin receptor 0.246
Cyp2c39 cytochrome P450, family 2, subfamily c, polypeptide 39 0.246
Keg1 kidney expressed gene 1 0.246
Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.243
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.243
Hgd homogentisate 1, 2-dioxygenase 0.241
Dmgdh dimethylglycine dehydrogenase precursor 0.241
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.239
Gstm3 glutathione S-transferase, mu 3 0.236
Mknk1 MAP kinase-interacting serine/threonine kinase 1 0.236
Cyp2d9 cytochrome P450, family 2, subfamily d, polypeptide 9 0.229
Vnn3 vanin 3 0.228
Asgr2 asialoglycoprotein receptor 2 0.224
Cyp2c68 cytochrome P450, family 2, subfamily c, polypeptide 68 0.222
Sult2a2 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2 0.216
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.208
Ppl periplakin 0.201
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.200
Bhmt betaine-homocysteine methyltransferase 0.200
Mbl2 mannose-binding lectin (protein C) 2 0.193
Rdh7 retinol dehydrogenase 7 0.191
Apoc3 apolipoprotein C-III 0.188
Fmo1 flavin containing monooxygenase 1 0.181
Ces1g carboxylesterase 1G 0.180
Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.171
Ces1c carboxylesterase 1C 0.167
Uox urate oxidase 0.167
Sult1b1 sulfotransferase family 1B, member 1 0.166
Mapk14 mitogen-activated protein kinase 14 0.159
Mapk8 mitogen-activated protein kinase 8 0.155
Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 0.154
Rdh16 retinol dehydrogenase 16 0.153
Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 0.149
Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.146
Krtap6-1 keratin associated protein 6-1 0.145
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.144
Acot12 acyl-CoA thioesterase 12 0.141
Agxt alanine-glyoxylate aminotransferase 0.140
Apoh apolipoprotein H 0.138
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.136
Fbp1 fructose bisphosphatase 1 0.135
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Mekk1 CG7717 gene product from transcript CG7717-RB 0.300
kay kayak 0.128
p38b CG7393 gene product from transcript CG7393-RA 0.101
Ric Ras which interacts with Calmodulin 0.054
hpo hippo 0.050
Mt2 Methyltransferase 2 0.046
MTF-1 Metal response element-binding Transcription Factor-1 0.045
Tak1 TGF-beta activated kinase 1 0.045
MP1 Melanization Protease 1 0.040
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.039
S6k RPS6-p70-protein kinase 0.031
puc puckered 0.026
Trx-2 thioredoxin-2 0.022
Fkbp13 CG9847 gene product from transcript CG9847-RC 0.019
chinmo Chronologically inappropriate morphogenesis 0.017
CG2118 CG2118 gene product from transcript CG2118-RB 0.015
PHGPx CG12013 gene product from transcript CG12013-RC 0.015
Aplip1 APP-like protein interacting protein 1 0.014
whd withered 0.013
yip2 yippee interacting protein 2 0.013
cert ceramide transfer protein 0.013
Chd64 CG14996 gene product from transcript CG14996-RB 0.013
Rel Relish 0.012
CG5335 CG5335 gene product from transcript CG5335-RA 0.011
bmm brummer 0.011
Aats-arg Arginyl-tRNA synthetase 0.011
Ser7 CG2045 gene product from transcript CG2045-RA 0.011
NLaz Neural Lazarillo 0.010
synj synaptojanin 0.010
Vps16A Vacuolar protein sorting 16A 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
MT1H metallothionein 1H 0.981
MT1E metallothionein 1E 0.976
MT1F metallothionein 1F 0.976
MT2A metallothionein 2A 0.559
MT1X metallothionein 1X 0.554
MAPK14 mitogen-activated protein kinase 14 0.397
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.183
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.173
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.132
MAP2K4 mitogen-activated protein kinase kinase 4 0.125
MT1G metallothionein 1G 0.078
MAPK1 mitogen-activated protein kinase 1 0.075
TTR transthyretin 0.069
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.028
MAPK3 mitogen-activated protein kinase 3 0.026
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.023
ARRB1 arrestin, beta 1 0.023
DUSP1 dual specificity phosphatase 1 0.021
JUN jun proto-oncogene 0.019
GPR50 G protein-coupled receptor 50 0.013
MT1M metallothionein 1M 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism
Vdac1 voltage-dependent anion channel 1 0.023
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.015
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.011
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
UBI4 Ubi4p 0.038
MRT4 Mrt4p 0.011