The network for 'respiratory gaseous exchange' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

respiratory gaseous exchange

The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.

Mus musculus
Name Description Probability Func Analog Organism
Eya1 eyes absent 1 homolog (Drosophila) 0.888
Nhlh1 nescient helix loop helix 1 0.730
Ednra endothelin receptor type A 0.615
Hoxa3 homeobox A3 0.606
Hoxb5 homeobox B5 0.604
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.553
Foxc2 forkhead box C2 0.551
Neurod1 neurogenic differentiation 1 0.544
Hoxa1 homeobox A1 0.544
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.523
Klc1 kinesin light chain 1 0.508
Hoxd3 homeobox D3 0.508
Hoxb4 homeobox B4 0.502
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.457
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.445
Hoxc5 homeobox C5 0.441
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.431
Tcfap2a transcription factor AP-2, alpha 0.429
Lmx1a LIM homeobox transcription factor 1 alpha 0.408
Ebf3 early B-cell factor 3 0.393
Hoxa5 homeobox A5 0.387
Hoxc6 homeobox C6 0.342
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.325
Pax3 paired box gene 3 0.314
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.310
Pax6 paired box gene 6 0.292
Hoxb2 homeobox B2 0.291
Grid1 glutamate receptor, ionotropic, delta 1 0.272
Atf4 activating transcription factor 4 0.271
Hoxa9 homeobox A9 0.267
Hoxb6 homeobox B6 0.266
Prrx1 paired related homeobox 1 0.257
Mab21l2 mab-21-like 2 (C. elegans) 0.248
Gabrb2 gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 0.240
Hoxa2 homeobox A2 0.236
Uncx UNC homeobox 0.218
Gpr50 G-protein-coupled receptor 50 0.212
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.211
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.210
Pou3f4 POU domain, class 3, transcription factor 4 0.209
Myog myogenin 0.204
Isl1 ISL1 transcription factor, LIM/homeodomain 0.196
Sox10 SRY-box containing gene 10 0.190
Phox2b paired-like homeobox 2b 0.185
Hoxb1 homeobox B1 0.184
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.176
Mapk8 mitogen-activated protein kinase 8 0.156
Gdnf glial cell line derived neurotrophic factor 0.156
Dll1 delta-like 1 (Drosophila) 0.155
Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex 0.154
Hand2 heart and neural crest derivatives expressed transcript 2 0.151
Lalba lactalbumin, alpha 0.144
Ebf2 early B-cell factor 2 0.138
Hoxc4 homeobox C4 0.137
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.136
Msx1 homeobox, msh-like 1 0.134
Hoxb9 homeobox B9 0.131
Tyr tyrosinase 0.126
Gsc goosecoid homeobox 0.125
Pbx1 pre B-cell leukemia transcription factor 1 0.120
Hoxb3 homeobox B3 0.118
Pitx3 paired-like homeodomain transcription factor 3 0.118
Hoxa11 homeobox A11 0.118
Zfp36 zinc finger protein 36 0.115
Rhag Rhesus blood group-associated A glycoprotein 0.115
En1 engrailed 1 0.114
Hif3a hypoxia inducible factor 3, alpha subunit 0.113
Neurog2 neurogenin 2 0.112
Rarg retinoic acid receptor, gamma 0.111
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.111
Dlk1 delta-like 1 homolog (Drosophila) 0.111
Twist2 twist homolog 2 (Drosophila) 0.102
Hoxc8 homeobox C8 0.102
Hand1 heart and neural crest derivatives expressed transcript 1 0.101
Sox14 SRY-box containing gene 14 0.100
Notch1 Notch gene homolog 1 (Drosophila) 0.099
Wnt6 wingless-related MMTV integration site 6 0.098
Neurog3 neurogenin 3 0.098
Prph2 peripherin 2 0.098
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.098
ND6 NADH dehydrogenase subunit 6 0.095
Dcx doublecortin 0.094
Crb1 crumbs homolog 1 (Drosophila) 0.092
Hmx3 H6 homeobox 3 0.092
Tbx1 T-box 1 0.091
Psen1 presenilin 1 0.090
Neurod4 neurogenic differentiation 4 0.089
Acvr1 activin A receptor, type 1 0.087
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.086
Prph peripherin 0.084
Dcc deleted in colorectal carcinoma 0.083
Msx2 homeobox, msh-like 2 0.081
Rho rhodopsin 0.081
Prrx2 paired related homeobox 2 0.081
Gata1 GATA binding protein 1 0.080
Rarb retinoic acid receptor, beta 0.079
Gabra1 gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 0.078
Znrf4 zinc and ring finger 4 0.077
Mecom MDS1 and EVI1 complex locus 0.077
Fgfr1 fibroblast growth factor receptor 1 0.075
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.333
TNNI1 troponin I type 1 (skeletal, slow) 0.318
FOS FBJ murine osteosarcoma viral oncogene homolog 0.161
ZFX zinc finger protein, X-linked 0.155
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.123
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.103
MAF v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) 0.102
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.100
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.100
ZNF512B zinc finger protein 512B 0.086
TCEAL5 transcription elongation factor A (SII)-like 5 0.067
GFI1B growth factor independent 1B transcription repressor 0.065
ARRDC3 arrestin domain containing 3 0.065
ARL4D ADP-ribosylation factor-like 4D 0.060
POLA2 polymerase (DNA directed), alpha 2 (70kD subunit) 0.058
HIPK2 homeodomain interacting protein kinase 2 0.055
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.044
USP9X ubiquitin specific peptidase 9, X-linked 0.042
SMAD9 SMAD family member 9 0.039
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.039
JUN jun proto-oncogene 0.038
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.035
ATN1 atrophin 1 0.035
BCL6 B-cell CLL/lymphoma 6 0.035
RGS2 regulator of G-protein signaling 2, 24kDa 0.033
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.033
ADORA2A adenosine A2a receptor 0.032
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.030
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.028
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.026
ARID1B AT rich interactive domain 1B (SWI1-like) 0.025
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.025
PPP1R15A protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.025
ING2 inhibitor of growth family, member 2 0.025
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.024
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.024
HOXA4 homeobox A4 0.024
CBLC Cas-Br-M (murine) ecotropic retroviral transforming sequence c 0.023
HCN2 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 0.023
HOXA10 homeobox A10 0.022
SKI v-ski sarcoma viral oncogene homolog (avian) 0.022
TNNI2 troponin I type 2 (skeletal, fast) 0.022
RBBP5 retinoblastoma binding protein 5 0.022
HOXA7 homeobox A7 0.022
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.021
MAST1 microtubule associated serine/threonine kinase 1 0.021
TNNT2 troponin T type 2 (cardiac) 0.021
NCF1 neutrophil cytosolic factor 1 0.021
EGR3 early growth response 3 0.020
EGR2 early growth response 2 0.020
MAP2K7 mitogen-activated protein kinase kinase 7 0.020
CCNL1 cyclin L1 0.020
RIC8A resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) 0.019
SMAD1 SMAD family member 1 0.019
NELL2 NEL-like 2 (chicken) 0.019
CRYZ crystallin, zeta (quinone reductase) 0.019
PDZD4 PDZ domain containing 4 0.018
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.018
DRD2 dopamine receptor D2 0.018
PRKCB protein kinase C, beta 0.018
NFIL3 nuclear factor, interleukin 3 regulated 0.017
MLL3 myeloid/lymphoid or mixed-lineage leukemia 3 0.017
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.017
KLF4 Kruppel-like factor 4 (gut) 0.017
TRIP6 thyroid hormone receptor interactor 6 0.017
ATF2 activating transcription factor 2 0.017
CYR61 cysteine-rich, angiogenic inducer, 61 0.016
MON1A MON1 homolog A (yeast) 0.016
HDAC4 histone deacetylase 4 0.016
HAND2 heart and neural crest derivatives expressed 2 0.016
NOTCH3 notch 3 0.016
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.016
NBR1 neighbor of BRCA1 gene 1 0.016
RAD23B RAD23 homolog B (S. cerevisiae) 0.016
TNNI3 troponin I type 3 (cardiac) 0.016
MLL2 myeloid/lymphoid or mixed-lineage leukemia 2 0.016
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.015
GADD45B growth arrest and DNA-damage-inducible, beta 0.015
JUNB jun B proto-oncogene 0.015
EGFL7 EGF-like-domain, multiple 7 0.015
BEGAIN brain-enriched guanylate kinase-associated homolog (rat) 0.015
KLF9 Kruppel-like factor 9 0.015
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.015
COL20A1 collagen, type XX, alpha 1 0.015
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.015
PHACTR3 phosphatase and actin regulator 3 0.015
MEIS1 Meis homeobox 1 0.015
DTX3 deltex homolog 3 (Drosophila) 0.015
PSAP prosaposin 0.015
SEPT11 septin 11 0.014
KLF5 Kruppel-like factor 5 (intestinal) 0.014
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.014
PELI1 pellino homolog 1 (Drosophila) 0.014
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.014
SGK1 serum/glucocorticoid regulated kinase 1 0.014
SGSH N-sulfoglucosamine sulfohydrolase 0.014
KLF10 Kruppel-like factor 10 0.014
TRIM9 tripartite motif containing 9 0.014
TMEM59L transmembrane protein 59-like 0.014
EGR1 early growth response 1 0.014
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ddn dendrin 0.331
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.202
Prkcg protein kinase C, gamma 0.093
Drd2 dopamine receptor D2 0.084
Dlg4 discs, large homolog 4 (Drosophila) 0.079
Vcsa1 variable coding sequence A1 0.078
Ncan neurocan 0.065
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.064
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.061
Pfkm phosphofructokinase, muscle 0.060
Galr2 galanin receptor 2 0.057
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.056
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.055
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.053
Rph3a rabphilin 3A 0.049
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.049
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.046
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.046
Chrm1 cholinergic receptor, muscarinic 1 0.045
Prkg2 protein kinase, cGMP-dependent, type II 0.045
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.045
Ncr1 natural cytotoxicity triggering receptor 1 0.045
Nfasc neurofascin 0.043
Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.043
Syn1 synapsin I 0.043
Slit1 slit homolog 1 (Drosophila) 0.043
Adora1 adenosine A1 receptor 0.041
Bcan brevican 0.041
Lin7b lin-7 homolog b (C. elegans) 0.040
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.040
Rgs9 regulator of G-protein signaling 9 0.039
Vom2r44 vomeronasal 2 receptor 44 0.039
Pla2g5 phospholipase A2, group V 0.038
Adora2a adenosine A2a receptor 0.038
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.037
Mbl2 mannose-binding lectin (protein C) 2 0.037
Arc activity-regulated cytoskeleton-associated protein 0.037
Fgfr2 fibroblast growth factor receptor 2 0.036
Ptpn5 protein tyrosine phosphatase, non-receptor type 5 0.036
Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type 0.035
Ar androgen receptor 0.035
Hpcal4 hippocalcin-like 4 0.034
Rgs14 regulator of G-protein signaling 14 0.034
Alox5 arachidonate 5-lipoxygenase 0.033
Tacr2 tachykinin receptor 2 0.033
Apba2 amyloid beta (A4) precursor protein-binding, family A, member 2 0.032
Gria1 glutamate receptor, ionotropic, AMPA 1 0.032
Scn5a sodium channel, voltage-gated, type V, alpha subunit 0.032
Cdh6 cadherin 6 0.032
Amph amphiphysin 0.032
Accn2 amiloride-sensitive cation channel 2, neuronal 0.031
Pygm phosphorylase, glycogen, muscle 0.031
S100b S100 calcium binding protein B 0.031
Chrna1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.030
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.030
Strn striatin, calmodulin binding protein 0.030
Gpr27 G protein-coupled receptor 27 0.030
Camkv CaM kinase-like vesicle-associated 0.029
Sycn syncollin 0.029
Fgf2 fibroblast growth factor 2 0.029
Rorb RAR-related orphan receptor B 0.029
Cartpt CART prepropeptide 0.029
Arpp21 cAMP-regulated phosphoprotein 21 0.028
Cnksr2 connector enhancer of kinase suppressor of Ras 2 0.028
Gpr20 G protein-coupled receptor 20 0.027
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.027
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.027
Gper G protein-coupled estrogen receptor 1 0.027
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.027
Hapln1 hyaluronan and proteoglycan link protein 1 0.027
Fcer1a Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.027
Olr1493 olfactory receptor gene Olr1493 0.027
Smad3 SMAD family member 3 0.027
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.026
Cma1 chymase 1, mast cell 0.026
Syn2 synapsin II 0.026
Ptafr platelet-activating factor receptor 0.026
Acox3 acyl-Coenzyme A oxidase 3, pristanoyl 0.026
Hnmt histamine N-methyltransferase 0.026
Kcnq2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.026
Gad2 glutamate decarboxylase 2 0.026
Nr2c2 nuclear receptor subfamily 2, group C, member 2 0.025
Nrxn1 neurexin 1 0.025
Chrm4 cholinergic receptor, muscarinic 4 0.025
Oprk1 opioid receptor, kappa 1 0.025
Olr416 olfactory receptor 416 0.025
Rab15 RAB15, member RAS oncogene family 0.025
Rab3b RAB3B, member RAS oncogene family 0.025
Ier5 immediate early response 5 0.025
Otx1 orthodenticle homeobox 1 0.024
Cntn5 contactin 5 0.024
Pigl phosphatidylinositol glycan anchor biosynthesis, class L 0.024
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.024
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.024
Trpc4 transient receptor potential cation channel, subfamily C, member 4 0.023
Prol1 proline rich, lacrimal 1 0.023
Dusp4 dual specificity phosphatase 4 0.023
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.023
Eps8 epidermal growth factor receptor pathway substrate 8 0.023
Synpo synaptopodin 0.023
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism