The network for 'regulation of platelet activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of platelet activation

Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.

Rattus norvegicus
Name Description Probability Func Analog Organism
Cd44 Cd44 molecule 0.110
Gja1 gap junction protein, alpha 1 0.079
Icam1 intercellular adhesion molecule 1 0.070
Ddr2 discoidin domain receptor tyrosine kinase 2 0.061
Olr1500 olfactory receptor 1500 0.054
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.052
Bst1 bone marrow stromal cell antigen 1 0.051
Ncan neurocan 0.049
Ccl4 chemokine (C-C motif) ligand 4 0.048
Axl Axl receptor tyrosine kinase 0.044
Itgb7 integrin, beta 7 0.042
Casp1 caspase 1 0.040
Rorb RAR-related orphan receptor B 0.040
Edn1 endothelin 1 0.039
Inpp5d inositol polyphosphate-5-phosphatase D 0.038
Ptafr platelet-activating factor receptor 0.038
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.038
Arl11 ADP-ribosylation factor-like 11 0.037
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.037
Phkg1 phosphorylase kinase, gamma 1 0.034
Pmp22 peripheral myelin protein 22 0.034
Pla1a phospholipase A1 member A 0.034
Fgf14 fibroblast growth factor 14 0.033
Plau plasminogen activator, urokinase 0.033
Ccl3 chemokine (C-C motif) ligand 3 0.032
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.032
Colec12 collectin sub-family member 12 0.030
Cma1 chymase 1, mast cell 0.030
Gpc3 glypican 3 0.030
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.029
Gna15 guanine nucleotide binding protein, alpha 15 0.029
Fn1 fibronectin 1 0.029
Hck hemopoietic cell kinase 0.028
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.027
Gucy2f guanylate cyclase 2F 0.027
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.026
Cd37 CD37 molecule 0.026
Bgn biglycan 0.026
Wipf1 WAS/WASL interacting protein family, member 1 0.026
Kcnq2 potassium voltage-gated channel, KQT-like subfamily, member 2 0.026
Fshb follicle stimulating hormone, beta polypeptide 0.026
Pecam1 platelet/endothelial cell adhesion molecule 1 0.025
Aebp1 AE binding protein 1 0.025
Gja4 gap junction protein, alpha 4 0.025
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.024
Pth parathyroid hormone 0.024
Cd83 CD83 molecule 0.024
Ltbp3 latent transforming growth factor beta binding protein 3 0.023
Agtr1a angiotensin II receptor, type 1a 0.023
Vcan versican 0.023
Runx1 runt-related transcription factor 1 0.023
Mmp12 matrix metallopeptidase 12 0.023
Ednrb endothelin receptor type B 0.023
Gpr88 G-protein coupled receptor 88 0.023
Homer3 homer homolog 3 (Drosophila) 0.023
RGD1564664 similar to LOC387763 protein 0.022
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.022
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.022
Il7 interleukin 7 0.022
Il1rap interleukin 1 receptor accessory protein 0.022
Cd247 Cd247 molecule 0.021
Slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 0.021
Gria4 glutamate receptor, ionotrophic, AMPA 4 0.021
Ly86 lymphocyte antigen 86 0.021
Tpsb2 tryptase beta 2 0.021
Crhbp corticotropin releasing hormone binding protein 0.021
Csrnp2 cysteine-serine-rich nuclear protein 2 0.020
Fat3 FAT tumor suppressor homolog 3 (Drosophila) 0.020
Npy5r neuropeptide Y receptor Y5 0.020
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.020
Ctrc chymotrypsin C (caldecrin) 0.020
Kcnk13 potassium channel, subfamily K, member 13 0.020
Cd5 Cd5 molecule 0.020
C5ar1 complement component 5a receptor 1 0.020
Ripk3 receptor-interacting serine-threonine kinase 3 0.020
LOC60591 calcium-activated potassium channel beta subunit 0.020
Olr287 olfactory receptor 287 0.020
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.020
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.020
Dock8 dedicator of cytokinesis 8 0.020
Fgf7 fibroblast growth factor 7 0.019
Lst1 leukocyte specific transcript 1 0.019
Kalrn kalirin, RhoGEF kinase 0.019
Lamc1 laminin, gamma 1 0.019
Prrx1 paired related homeobox 1 0.019
Il6 interleukin 6 0.019
Olr1523 olfactory receptor 1523 0.019
Gad2 glutamate decarboxylase 2 0.019
Adam17 ADAM metallopeptidase domain 17 0.019
Mmp9 matrix metallopeptidase 9 0.019
Rhoj ras homolog gene family, member J 0.019
Athl1 ATH1, acid trehalase-like 1 (yeast) 0.019
Tal1 T-cell acute lymphocytic leukemia 1 0.018
Cxcl2 chemokine (C-X-C motif) ligand 2 0.018
Cryge crystallin, gamma E 0.018
Il1b interleukin 1 beta 0.018
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.018
S1pr2 sphingosine-1-phosphate receptor 2 0.018
Sla src-like adaptor 0.018
A3galt2 alpha 1,3-galactosyltransferase 2 0.018
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.812
NCF1 neutrophil cytosolic factor 1 0.750
C1QA complement component 1, q subcomponent, A chain 0.690
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.646
VEGFA vascular endothelial growth factor A 0.473
PLCG1 phospholipase C, gamma 1 0.395
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.221
NRP1 neuropilin 1 0.173
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.168
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.149
SYK spleen tyrosine kinase 0.087
C1QC complement component 1, q subcomponent, C chain 0.064
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 0.060
CTNND1 catenin (cadherin-associated protein), delta 1 0.050
EGFR epidermal growth factor receptor 0.049
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.046
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.041
LAT linker for activation of T cells 0.038
FASLG Fas ligand (TNF superfamily, member 6) 0.035
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.029
C1QB complement component 1, q subcomponent, B chain 0.028
GAB1 GRB2-associated binding protein 1 0.027
LCK lymphocyte-specific protein tyrosine kinase 0.025
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.022
CDH5 cadherin 5, type 2 (vascular endothelium) 0.021
PGF placental growth factor 0.019
HP haptoglobin 0.018
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.017
APOC1 apolipoprotein C-I 0.015
LY96 lymphocyte antigen 96 0.014
LCAT lecithin-cholesterol acyltransferase 0.014
PDGFA platelet-derived growth factor alpha polypeptide 0.013
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.012
BTK Bruton agammaglobulinemia tyrosine kinase 0.012
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.011
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.011
ZNF746 zinc finger protein 746 0.011
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.010
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.010
KITLG KIT ligand 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Lck lymphocyte protein tyrosine kinase 0.910
Ldb3 LIM domain binding 3 0.887
Ptprc protein tyrosine phosphatase, receptor type, C 0.832
Fas Fas (TNF receptor superfamily member 6) 0.622
Selp selectin, platelet 0.579
Prkce protein kinase C, epsilon 0.446
Lat linker for activation of T cells 0.444
Il2rg interleukin 2 receptor, gamma chain 0.399
Blnk B-cell linker 0.373
Lyz2 lysozyme 2 0.358
Fyn Fyn proto-oncogene 0.342
Ikzf1 IKAROS family zinc finger 1 0.312
Rag2 recombination activating gene 2 0.302
Cd28 CD28 antigen 0.246
Nos3 nitric oxide synthase 3, endothelial cell 0.238
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.222
Cd19 CD19 antigen 0.212
Tcra T-cell receptor alpha chain 0.174
Ccr2 chemokine (C-C motif) receptor 2 0.171
Sykb spleen tyrosine kinase 0.138
Igh immunoglobulin heavy chain complex 0.124
Ush1g Usher syndrome 1G homolog (human) 0.116
Src Rous sarcoma oncogene 0.112
Itgb3 integrin beta 3 0.095
Lcp1 lymphocyte cytosolic protein 1 0.083
Zap70 zeta-chain (TCR) associated protein kinase 0.079
Ush1c Usher syndrome 1C homolog (human) 0.078
Pparg peroxisome proliferator activated receptor gamma 0.076
Sele selectin, endothelial cell 0.075
Actn2 actinin alpha 2 0.070
Prkcb protein kinase C, beta 0.069
Cdh5 cadherin 5 0.066
Sell selectin, lymphocyte 0.065
Tnf tumor necrosis factor 0.065
Alox5ap arachidonate 5-lipoxygenase activating protein 0.062
Was Wiskott-Aldrich syndrome homolog (human) 0.062
Fyb FYN binding protein 0.059
Mmp9 matrix metallopeptidase 9 0.059
Ptpre protein tyrosine phosphatase, receptor type, E 0.058
Orai1 ORAI calcium release-activated calcium modulator 1 0.057
Bcl2 B-cell leukemia/lymphoma 2 0.057
Il7r interleukin 7 receptor 0.057
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.055
Nfam1 Nfat activating molecule with ITAM motif 1 0.054
Grxcr1 glutaredoxin, cysteine rich 1 0.053
Sirpa signal-regulatory protein alpha 0.051
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.051
Cbl Casitas B-lineage lymphoma 0.050
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.049
Plcd1 phospholipase C, delta 1 0.049
Pten phosphatase and tensin homolog 0.049
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.049
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.048
Cd4 CD4 antigen 0.048
Ptk2 PTK2 protein tyrosine kinase 2 0.047
Cd14 CD14 antigen 0.047
Vhl von Hippel-Lindau tumor suppressor 0.042
Grb2 growth factor receptor bound protein 2 0.042
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.042
Myo6 myosin VI 0.041
Whrn whirlin 0.039
Ticam1 toll-like receptor adaptor molecule 1 0.038
Ncoa3 nuclear receptor coactivator 3 0.036
ND6 NADH dehydrogenase subunit 6 0.036
Cx3cr1 chemokine (C-X3-C) receptor 1 0.035
Rasgrp1 RAS guanyl releasing protein 1 0.034
Rag1 recombination activating gene 1 0.034
Cd22 CD22 antigen 0.034
Blk B lymphoid kinase 0.033
Sla src-like adaptor 0.033
Rgs14 regulator of G-protein signaling 14 0.033
Notch2 Notch gene homolog 2 (Drosophila) 0.033
Itgb2 integrin beta 2 0.033
Csf1 colony stimulating factor 1 (macrophage) 0.032
Il2rb interleukin 2 receptor, beta chain 0.032
LOC100503041 PDZ domain-containing protein 7-like 0.031
Foxn1 forkhead box N1 0.030
Itk IL2-inducible T-cell kinase 0.030
Pik3cg phosphoinositide-3-kinase, catalytic, gamma polypeptide 0.029
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.028
Inpp5d inositol polyphosphate-5-phosphatase D 0.028
Akt1 thymoma viral proto-oncogene 1 0.028
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.026
Asprv1 aspartic peptidase, retroviral-like 1 0.025
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.025
Ccl4 chemokine (C-C motif) ligand 4 0.025
Cd247 CD247 antigen 0.025
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.024
Cd40 CD40 antigen 0.023
Fcgr1 Fc receptor, IgG, high affinity I 0.023
Fbxw7 F-box and WD-40 domain protein 7 0.022
Myo7a myosin VIIA 0.022
Lair1 leukocyte-associated Ig-like receptor 1 0.022
Cmklr1 chemokine-like receptor 1 0.022
Hcst hematopoietic cell signal transducer 0.021
Fam65b family with sequence similarity 65, member B 0.021
Nfib nuclear factor I/B 0.021
Ms4a4c membrane-spanning 4-domains, subfamily A, member 4C 0.021
Itga2b integrin alpha 2b 0.020
Myo15 myosin XV 0.020
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism