The network for 'regulation of muscle cell apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of muscle cell apoptotic process

Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.

Rattus norvegicus
Name Description Probability Func Analog Organism
Jak2 Janus kinase 2 0.417
LOC100362824 caveolin 2-like 0.178
Cd4 Cd4 molecule 0.128
Soat1 sterol O-acyltransferase 1 0.117
Fgfr2 fibroblast growth factor receptor 2 0.111
Strn striatin, calmodulin binding protein 0.071
Pde5a phosphodiesterase 5A, cGMP-specific 0.061
Smad1 SMAD family member 1 0.057
Edn1 endothelin 1 0.055
Jak1 Janus kinase 1 0.039
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.037
Gata6 GATA binding protein 6 0.036
Emp1 epithelial membrane protein 1 0.036
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.033
Tgfbr3 transforming growth factor, beta receptor III 0.032
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.031
Sell selectin L 0.030
Ddr1 discoidin domain receptor tyrosine kinase 1 0.030
Sept2 septin 2 0.029
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.026
Smad3 SMAD family member 3 0.025
Foxe3 forkhead box E3 0.025
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.025
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.025
Cyp51 cytochrome P450, family 51 0.025
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.023
Pdgfb platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.022
Cd38 CD38 molecule 0.022
Socs5 suppressor of cytokine signaling 5 0.022
Met met proto-oncogene 0.022
Nfib nuclear factor I/B 0.022
Grm5 glutamate receptor, metabotropic 5 0.021
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.021
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.020
Ccbp2 chemokine binding protein 2 0.020
Efna5 ephrin A5 0.020
Slc22a9 solute carrier family 22 (organic anion transporter), member 9 0.020
Bmp6 bone morphogenetic protein 6 0.019
Csnk1g2 casein kinase 1, gamma 2 0.019
Calcrl calcitonin receptor-like 0.019
Nfia nuclear factor I/A 0.018
Casp3 caspase 3 0.018
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.018
Fgf11 fibroblast growth factor 11 0.018
Sdc3 syndecan 3 0.018
Lims1 LIM and senescent cell antigen-like domains 1 0.017
Il1rap interleukin 1 receptor accessory protein 0.017
Smad7 SMAD family member 7 0.017
Kcnq1 potassium voltage-gated channel, KQT-like subfamily, member 1 0.017
Wisp1 WNT1 inducible signaling pathway protein 1 0.017
Sycn syncollin 0.016
Sc4mol sterol-C4-methyl oxidase-like 0.016
Pls3 plastin 3 (T-isoform) 0.016
Stat3 signal transducer and activator of transcription 3 0.016
Adrb1 adrenergic, beta-1-, receptor 0.016
Pitx3 paired-like homeodomain 3 0.015
Hapln1 hyaluronan and proteoglycan link protein 1 0.015
Sp1 Sp1 transcription factor 0.015
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.015
Map3k3 mitogen activated protein kinase kinase kinase 3 0.015
Mdm2 Mdm2 p53 binding protein homolog (mouse) 0.015
Kcnmb1 potassium large conductance calcium-activated channel, subfamily M, beta member 1 0.015
Testin testin gene 0.015
Tgfbr2 transforming growth factor, beta receptor II 0.014
Glra1 glycine receptor, alpha 1 0.014
Ncf1 neutrophil cytosolic factor 1 0.014
Tgfbr1 transforming growth factor, beta receptor 1 0.014
Pdcl phosducin-like 0.014
Agtr1a angiotensin II receptor, type 1a 0.014
Asah1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.014
Nmur2 neuromedin U receptor 2 0.014
Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.014
Rnf4 ring finger protein 4 0.014
Vom2r27 vomeronasal 2 receptor, 27 0.014
Pecam1 platelet/endothelial cell adhesion molecule 1 0.014
Ptprk protein tyrosine phosphatase, receptor type, K, extracellular region 0.014
Lig3 ligase III, DNA, ATP-dependent 0.014
Mrgprf MAS-related GPR, member F 0.014
Ubtf upstream binding transcription factor, RNA polymerase I 0.014
Pdzd2 PDZ domain containing 2 0.013
Hist1h1d histone cluster 1, H1d 0.013
Foxd3 forkhead box D3 0.013
Actc1 actin, alpha, cardiac muscle 1 0.013
Tpm4 tropomyosin 4 0.013
Aanat arylalkylamine N-acetyltransferase 0.013
Igfbp5 insulin-like growth factor binding protein 5 0.013
Mr1 major histocompatibility complex, class I-related 0.013
Crybb3 crystallin, beta B3 0.013
Yipf4 Yip1 domain family, member 4 0.013
Kl Klotho 0.013
Irs1 insulin receptor substrate 1 0.013
Dhrs9 dehydrogenase/reductase (SDR family) member 9 0.013
Wdr62 WD repeat domain 62 0.013
Pdyn prodynorphin 0.013
Pim1 pim-1 oncogene 0.013
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.013
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.013
Sct secretin 0.013
Nppc natriuretic peptide precursor C 0.012
Tmem171 transmembrane protein 171 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 0.524
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.208
ARRB1 arrestin, beta 1 0.050
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.029
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.024
IL23A interleukin 23, alpha subunit p19 0.022
GRB10 growth factor receptor-bound protein 10 0.016
LRRK2 leucine-rich repeat kinase 2 0.015
GSK3B glycogen synthase kinase 3 beta 0.014
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.014
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.013
ITGB1BP3 integrin beta 1 binding protein 3 0.012
IRS1 insulin receptor substrate 1 0.012
HSPB1 heat shock 27kDa protein 1 0.012
HSPB8 heat shock 22kDa protein 8 0.011
IGF2R insulin-like growth factor 2 receptor 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.892
Hand2 heart and neural crest derivatives expressed transcript 2 0.884
Hand1 heart and neural crest derivatives expressed transcript 1 0.841
Neurod1 neurogenic differentiation 1 0.811
Shh sonic hedgehog 0.789
Ptf1a pancreas specific transcription factor, 1a 0.778
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.724
Pten phosphatase and tensin homolog 0.672
Emx1 empty spiracles homolog 1 (Drosophila) 0.634
Isl1 ISL1 transcription factor, LIM/homeodomain 0.608
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.556
Mdm2 transformed mouse 3T3 cell double minute 2 0.446
Otx2 orthodenticle homolog 2 (Drosophila) 0.437
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.433
Gata4 GATA binding protein 4 0.395
Trp53 transformation related protein 53 0.364
Neurog2 neurogenin 2 0.353
Pax6 paired box gene 6 0.335
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.331
Tbx5 T-box 5 0.326
Tgfbr2 transforming growth factor, beta receptor II 0.306
Insm1 insulinoma-associated 1 0.261
Pthlh parathyroid hormone-like peptide 0.257
Mecom MDS1 and EVI1 complex locus 0.256
Ntf3 neurotrophin 3 0.251
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.249
Hoxd13 homeobox D13 0.246
Hoxa1 homeobox A1 0.241
Sox9 SRY-box containing gene 9 0.224
Kiss1 KiSS-1 metastasis-suppressor 0.214
Sfrp2 secreted frizzled-related protein 2 0.188
Apc adenomatosis polyposis coli 0.185
Prph2 peripherin 2 0.173
Fgf8 fibroblast growth factor 8 0.165
Sfrp1 secreted frizzled-related protein 1 0.164
Gli2 GLI-Kruppel family member GLI2 0.161
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.155
Col1a1 collagen, type I, alpha 1 0.152
Pdx1 pancreatic and duodenal homeobox 1 0.147
Grb10 growth factor receptor bound protein 10 0.133
Nf1 neurofibromatosis 1 0.130
Gata1 GATA binding protein 1 0.119
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.116
Nos3 nitric oxide synthase 3, endothelial cell 0.114
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.112
Foxc2 forkhead box C2 0.110
Rxra retinoid X receptor alpha 0.104
Ep300 E1A binding protein p300 0.102
Lepr leptin receptor 0.100
T brachyury 0.099
Nkx6-1 NK6 homeobox 1 0.092
Socs1 suppressor of cytokine signaling 1 0.091
Gp9 glycoprotein 9 (platelet) 0.090
Pax3 paired box gene 3 0.086
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.085
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.083
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.083
Sox11 SRY-box containing gene 11 0.082
Rb1 retinoblastoma 1 0.077
Tgfb2 transforming growth factor, beta 2 0.076
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.074
Igf2 insulin-like growth factor 2 0.073
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.072
Gsk3b glycogen synthase kinase 3 beta 0.067
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.065
Neurog3 neurogenin 3 0.060
Fbn1 fibrillin 1 0.058
Lep leptin 0.055
Npc1 Niemann Pick type C1 0.054
Mdm4 transformed mouse 3T3 cell double minute 4 0.054
Trp63 transformation related protein 63 0.053
Alx3 aristaless-like homeobox 3 0.053
Bmpr1a bone morphogenetic protein receptor, type 1A 0.052
Msx1 homeobox, msh-like 1 0.051
Meox2 mesenchyme homeobox 2 0.050
Tbx1 T-box 1 0.049
Phox2b paired-like homeobox 2b 0.048
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.047
Hes5 hairy and enhancer of split 5 (Drosophila) 0.047
Cdh23 cadherin 23 (otocadherin) 0.046
Mesp1 mesoderm posterior 1 0.046
Wnt6 wingless-related MMTV integration site 6 0.046
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.045
Utf1 undifferentiated embryonic cell transcription factor 1 0.045
Nhlh1 nescient helix loop helix 1 0.045
Smn1 survival motor neuron 1 0.044
Arx aristaless related homeobox 0.044
Esx1 extraembryonic, spermatogenesis, homeobox 1 0.044
Rprm reprimo, TP53 dependent G2 arrest mediator candidate 0.043
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.042
Onecut1 one cut domain, family member 1 0.042
Pax9 paired box gene 9 0.042
Gata6 GATA binding protein 6 0.041
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.041
Rpl4 ribosomal protein L4 0.040
Mdfi MyoD family inhibitor 0.040
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.040
Adam17 a disintegrin and metallopeptidase domain 17 0.039
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.039
En1 engrailed 1 0.038
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism