The network for 'hippocampus development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

hippocampus development

The progression of the hippocampus over time from its initial formation until its mature state.

Name Description Probability Func Analog Organism
Lgals3 lectin, galactoside-binding, soluble, 3 0.177
Tlr4 toll-like receptor 4 0.103
Neurod2 neurogenic differentiation 2 0.094
Dlg4 discs, large homolog 4 (Drosophila) 0.088
Nkx6-1 NK6 homeobox 1 0.065
Nme1 non-metastatic cells 1, protein (NM23A) expressed in 0.064
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.064
S100a10 S100 calcium binding protein A10 0.061
Npy5r neuropeptide Y receptor Y5 0.061
Bcan brevican 0.056
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.050
Dbp D site of albumin promoter (albumin D-box) binding protein 0.050
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.046
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.045
Lrrc7 leucine rich repeat containing 7 0.044
Hoxa2 homeo box A2 0.043
Aqp4 aquaporin 4 0.040
Shank1 SH3 and multiple ankyrin repeat domains 1 0.039
Anxa2 annexin A2 0.039
S100a11 S100 calcium binding protein A11 (calizzarin) 0.038
Cckbr cholecystokinin B receptor 0.038
Gabbr2 gamma-aminobutyric acid (GABA) B receptor 2 0.038
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.035
Chrm1 cholinergic receptor, muscarinic 1 0.034
Ppia peptidylprolyl isomerase A (cyclophilin A) 0.034
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.033
Anxa5 annexin A5 0.033
Egr3 early growth response 3 0.033
Ppy pancreatic polypeptide 0.033
Adra2c adrenergic, alpha-2C-, receptor 0.032
Casp2 caspase 2 0.032
Synpo synaptopodin 0.031
Pgam1 phosphoglycerate mutase 1 (brain) 0.031
Nat1 N-acetyltransferase 1 0.031
Acrv1 acrosomal vesicle protein 1 0.031
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.030
Vcsa1 variable coding sequence A1 0.030
Olr1493 olfactory receptor gene Olr1493 0.029
Casp3 caspase 3 0.028
Cr1l complement component (3b/4b) receptor 1-like 0.028
S100a6 S100 calcium binding protein A6 0.028
Mll5 myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila) 0.028
Myo1d myosin ID 0.028
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.027
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.027
Gja4 gap junction protein, alpha 4 0.027
Prdx2 peroxiredoxin 2 0.027
Ptprc protein tyrosine phosphatase, receptor type, C 0.026
Gse1 genetic suppressor element 1 0.026
Slc25a5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.025
Cd9 CD9 molecule 0.025
Trim29 tripartite motif-containing 29 0.025
Gabrg3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.025
Jak1 Janus kinase 1 0.025
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.025
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.024
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.024
Mdh1 malate dehydrogenase 1, NAD (soluble) 0.024
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.024
Psmb5 proteasome (prosome, macropain) subunit, beta type 5 0.024
Rup2 urinary protein 2 0.023
Pou3f3 POU class 3 homeobox 3 0.023
Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) 0.023
Ptch1 patched homolog 1 (Drosophila) 0.023
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.023
Slc16a8 solute carrier family 16, member 8 (monocarboxylic acid transporter 3) 0.023
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.023
Ctsc cathepsin C 0.023
Galnt5 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) 0.023
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.023
Crhbp corticotropin releasing hormone binding protein 0.023
Ar androgen receptor 0.022
Retnla resistin like alpha 0.022
Cnga2 cyclic nucleotide gated channel alpha 2 0.022
Il12b interleukin 12B 0.022
Casp7 caspase 7 0.022
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.022
Dad1 defender against cell death 1 0.022
Impg2 interphotoreceptor matrix proteoglycan 2 0.022
Pomp proteasome maturation protein 0.021
Abcc2 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 0.021
Klk8 kallikrein related-peptidase 8 0.021
Hrh2 histamine receptor H 2 0.021
Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.021
Tnr tenascin R 0.021
Kcnc3 potassium voltage gated channel, Shaw-related subfamily, member 3 0.021
Csrnp2 cysteine-serine-rich nuclear protein 2 0.020
Stx2 syntaxin 2 0.020
Pou3f1 POU class 3 homeobox 1 0.020
Cd36 CD36 molecule (thrombospondin receptor) 0.020
Svs1 seminal vesicle secretory protein 1 0.020
Gria2 glutamate receptor, ionotropic, AMPA 2 0.020
Ppard peroxisome proliferator-activated receptor delta 0.020
Grik3 glutamate receptor, ionotropic, kainate 3 0.020
Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.020
Fgf7 fibroblast growth factor 7 0.020
Arpc1b actin related protein 2/3 complex, subunit 1B 0.020
Trpc4 transient receptor potential cation channel, subfamily C, member 4 0.020
Dhfr dihydrofolate reductase 0.020
Nrxn3 neurexin 3 0.020
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HDAC1 histone deacetylase 1 0.987
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.954
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.845
TSC2 tuberous sclerosis 2 0.842
DLG4 discs, large homolog 4 (Drosophila) 0.766
RXRA retinoid X receptor, alpha 0.720
BBS2 Bardet-Biedl syndrome 2 0.685
USP46 ubiquitin specific peptidase 46 0.620
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.613
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.561
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.475
NDEL1 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 0.365
SCHIP1 schwannomin interacting protein 1 0.352
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.333
APAF1 apoptotic peptidase activating factor 1 0.298
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.246
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.235
BBS9 Bardet-Biedl syndrome 9 0.227
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.188
MKL1 megakaryoblastic leukemia (translocation) 1 0.187
RPL18A ribosomal protein L18a 0.168
WWOX WW domain containing oxidoreductase 0.162
XIAP X-linked inhibitor of apoptosis 0.159
MYOCD myocardin 0.154
GSK3B glycogen synthase kinase 3 beta 0.145
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.138
SKI v-ski sarcoma viral oncogene homolog (avian) 0.130
DCTN1 dynactin 1 0.122
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.117
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.116
HNF4A hepatocyte nuclear factor 4, alpha 0.107
AXIN1 axin 1 0.104
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.095
CREBBP CREB binding protein 0.093
SCRIB scribbled homolog (Drosophila) 0.093
ALK anaplastic lymphoma receptor tyrosine kinase 0.092
MED25 mediator complex subunit 25 0.090
LRP6 low density lipoprotein receptor-related protein 6 0.088
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.088
APTX aprataxin 0.087
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.085
NCOR2 nuclear receptor corepressor 2 0.083
CDK5 cyclin-dependent kinase 5 0.082
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.081
EGR1 early growth response 1 0.080
ZHX1 zinc fingers and homeoboxes 1 0.078
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.077
PCM1 pericentriolar material 1 0.076
SPRR2A small proline-rich protein 2A 0.074
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.074
KDM6A lysine (K)-specific demethylase 6A 0.074
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.074
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.073
MYOG myogenin (myogenic factor 4) 0.072
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.072
FOS FBJ murine osteosarcoma viral oncogene homolog 0.070
MYOD1 myogenic differentiation 1 0.070
HDAC2 histone deacetylase 2 0.070
PTN pleiotrophin 0.069
PAX8 paired box 8 0.068
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.065
WDR48 WD repeat domain 48 0.064
EGR3 early growth response 3 0.063
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.063
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.062
CLIP1 CAP-GLY domain containing linker protein 1 0.061
USP12 ubiquitin specific peptidase 12 0.061
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.059
SPOP speckle-type POZ protein 0.058
HDAC3 histone deacetylase 3 0.057
PDX1 pancreatic and duodenal homeobox 1 0.053
MKL2 MKL/myocardin-like 2 0.052
QKI quaking homolog, KH domain RNA binding (mouse) 0.051
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.051
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.051
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.050
NLGN1 neuroligin 1 0.050
LAMA4 laminin, alpha 4 0.049
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.049
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.048
CABLES1 Cdk5 and Abl enzyme substrate 1 0.047
NPEPPS aminopeptidase puromycin sensitive 0.047
PDE4D phosphodiesterase 4D, cAMP-specific 0.046
BBS1 Bardet-Biedl syndrome 1 0.046
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.044
PPARA peroxisome proliferator-activated receptor alpha 0.042
ARL4D ADP-ribosylation factor-like 4D 0.042
BAI1 brain-specific angiogenesis inhibitor 1 0.042
EGR2 early growth response 2 0.041
TCF4 transcription factor 4 0.041
LHX3 LIM homeobox 3 0.040
PNKP polynucleotide kinase 3'-phosphatase 0.040
YAP1 Yes-associated protein 1 0.039
DEAF1 deformed epidermal autoregulatory factor 1 (Drosophila) 0.038
WDR20 WD repeat domain 20 0.038
STK36 serine/threonine kinase 36 0.037
MAP2K4 mitogen-activated protein kinase kinase 4 0.037
BCL6 B-cell CLL/lymphoma 6 0.036
BIRC2 baculoviral IAP repeat containing 2 0.036
SIX3 SIX homeobox 3 0.035
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Mus musculus
Name Description Probability Func Analog Organism
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Shh sonic hedgehog 1.000
Emx1 empty spiracles homolog 1 (Drosophila) 0.999
Pax6 paired box gene 6 0.997
Pax2 paired box gene 2 0.997
Gli3 GLI-Kruppel family member GLI3 0.996
Dab1 disabled homolog 1 (Drosophila) 0.989
Pax3 paired box gene 3 0.988
Lhx1 LIM homeobox protein 1 0.972
Rarg retinoic acid receptor, gamma 0.971
Lef1 lymphoid enhancer binding factor 1 0.971
Sox2 SRY-box containing gene 2 0.970
Ctnnb1 catenin (cadherin associated protein), beta 1 0.970
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.965
Fgf10 fibroblast growth factor 10 0.950
Msx1 homeobox, msh-like 1 0.942
Fgf8 fibroblast growth factor 8 0.938
Gli2 GLI-Kruppel family member GLI2 0.935
Dlx5 distal-less homeobox 5 0.923
Bbs4 Bardet-Biedl syndrome 4 (human) 0.915
Lmx1b LIM homeobox transcription factor 1 beta 0.903
Foxg1 forkhead box G1 0.890
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.884
Fgfr1 fibroblast growth factor receptor 1 0.883
Foxc2 forkhead box C2 0.877
Foxc1 forkhead box C1 0.876
Adrb1 adrenergic receptor, beta 1 0.876
Sox9 SRY-box containing gene 9 0.870
Nog noggin 0.852
Neurod1 neurogenic differentiation 1 0.848
Trp63 transformation related protein 63 0.835
Lhx5 LIM homeobox protein 5 0.827
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.816
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.811
Fgfr2 fibroblast growth factor receptor 2 0.802
Efnb2 ephrin B2 0.800
Emx2 empty spiracles homolog 2 (Drosophila) 0.798
Hoxd13 homeobox D13 0.794
Isl1 ISL1 transcription factor, LIM/homeodomain 0.778
Pou3f3 POU domain, class 3, transcription factor 3 0.776
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.773
Hand2 heart and neural crest derivatives expressed transcript 2 0.771
Gsc goosecoid homeobox 0.763
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.759
Hes5 hairy and enhancer of split 5 (Drosophila) 0.756
Prrx1 paired related homeobox 1 0.756
Kiss1 KiSS-1 metastasis-suppressor 0.755
En1 engrailed 1 0.754
Epha4 Eph receptor A4 0.724
Tsc2 tuberous sclerosis 2 0.717
Atoh7 atonal homolog 7 (Drosophila) 0.707
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.674
Dlx1 distal-less homeobox 1 0.674
Ret ret proto-oncogene 0.673
Nodal nodal 0.665
Tcfap2a transcription factor AP-2, alpha 0.661
Sox3 SRY-box containing gene 3 0.652
Hoxa1 homeobox A1 0.638
Bmp7 bone morphogenetic protein 7 0.635
Dlx2 distal-less homeobox 2 0.634
Neurog3 neurogenin 3 0.626
Hoxd11 homeobox D11 0.622
Insm1 insulinoma-associated 1 0.617
Gdnf glial cell line derived neurotrophic factor 0.616
Hoxa13 homeobox A13 0.606
Smo smoothened homolog (Drosophila) 0.589
Bmp4 bone morphogenetic protein 4 0.572
Wnt7a wingless-related MMTV integration site 7A 0.562
Pitx2 paired-like homeodomain transcription factor 2 0.558
Zfpm2 zinc finger protein, multitype 2 0.547
T brachyury 0.542
Twist2 twist homolog 2 (Drosophila) 0.541
Adra2b adrenergic receptor, alpha 2b 0.540
Gata4 GATA binding protein 4 0.537
Shc3 src homology 2 domain-containing transforming protein C3 0.514
Hdac2 histone deacetylase 2 0.513
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.503
Wnt6 wingless-related MMTV integration site 6 0.499
Dlx6 distal-less homeobox 6 0.499
Hoxa10 homeobox A10 0.494
Pou3f2 POU domain, class 3, transcription factor 2 0.484
Runx1t1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.473
Hmx3 H6 homeobox 3 0.462
Pbx1 pre B-cell leukemia transcription factor 1 0.461
Pthlh parathyroid hormone-like peptide 0.460
Ptk7 PTK7 protein tyrosine kinase 7 0.459
Hes1 hairy and enhancer of split 1 (Drosophila) 0.456
Ephb2 Eph receptor B2 0.455
Wnt3a wingless-related MMTV integration site 3A 0.452
Id1 inhibitor of DNA binding 1 0.451
Tlx3 T-cell leukemia, homeobox 3 0.449
Tbx1 T-box 1 0.447
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.443
Lhx3 LIM homeobox protein 3 0.441
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.440
Phox2b paired-like homeobox 2b 0.439
Trp53 transformation related protein 53 0.438
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.434
Mmp24 matrix metallopeptidase 24 0.430
Rarb retinoic acid receptor, beta 0.430
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism