Process View
The network for 'progesterone biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.424 | |
| Gabarapl2 | GABA(A) receptor-associated protein like 2 | 0.148 | |
| Hibadh | 3-hydroxyisobutyrate dehydrogenase | 0.145 | |
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.129 | |
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.098 | |
| Star | steroidogenic acute regulatory protein | 0.074 | |
| Rup2 | urinary protein 2 | 0.067 | |
| Cyp4a10 | cytochrome P450, family 4, subfamily a, polypeptide 10 | 0.064 | |
| Cox6c | cytochrome c oxidase, subunit VIc | 0.061 | |
| Prss3 | protease, serine, 3 | 0.055 | |
| Echs1 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 0.054 | |
| Abhd14b | abhydrolase domain containing 14b | 0.053 | |
| Pla2g16 | phospholipase A2, group XVI | 0.051 | |
| Scnn1g | sodium channel, nonvoltage-gated 1, gamma | 0.048 | |
| Nlrp6 | NLR family, pyrin domain containing 6 | 0.046 | |
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.044 | |
| Prl7d1 | prolactin family 7, subfamily d, member 1 | 0.044 | |
| Omd | osteomodulin | 0.042 | |
| Fam108b1 | family with sequence similarity 108, member B1 | 0.041 | |
| Hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 0.039 | |
| Hrh2 | histamine receptor H 2 | 0.038 | |
| Gucy2f | guanylate cyclase 2F | 0.037 | |
| Acadm | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 0.037 | |
| Si | sucrase-isomaltase (alpha-glucosidase) | 0.035 | |
| Smpx | small muscle protein, X-linked | 0.033 | |
| Scgb2a1 | secretoglobin, family 2A, member 1 | 0.033 | |
| RGD1304731 | similar to RIKEN cDNA 5330437I02 gene | 0.032 | |
| Tspy1 | testis specific protein, Y-linked 1 | 0.032 | |
| Slc9a3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.031 | |
| Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.029 | |
| Vom1r105 | vomeronasal 1 receptor 105 | 0.028 | |
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.028 | |
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.028 | |
| Mcee | methylmalonyl CoA epimerase | 0.027 | |
| Slc22a25 | solute carrier family 22, member 25 | 0.027 | |
| Hoxb8 | homeo box B8 | 0.027 | |
| Aqp8 | aquaporin 8 | 0.025 | |
| Naglt1 | Na+ dependent glucose transporter 1 | 0.024 | |
| Chrna3 | cholinergic receptor, nicotinic, alpha 3 | 0.024 | |
| Faslg | Fas ligand (TNF superfamily, member 6) | 0.024 | |
| Apoh | apolipoprotein H (beta-2-glycoprotein I) | 0.024 | |
| Ppyr1 | pancreatic polypeptide receptor 1 | 0.023 | |
| Rln1 | relaxin 1 | 0.023 | |
| Hbg1 | hemoglobin, gamma A | 0.023 | |
| LOC100361547 | Cytochrome P450, family 2, subfamily c, polypeptide 7-like | 0.022 | |
| Hcrtr2 | hypocretin (orexin) receptor 2 | 0.022 | |
| Atp4b | ATPase, H+/K+ exchanging, beta polypeptide | 0.022 | |
| Cyb5a | cytochrome b5 type A (microsomal) | 0.021 | |
| Spt1 | salivary protein 1 | 0.021 | |
| Clca4 | chloride channel accessory 4 | 0.021 | |
| Rhag | Rh-associated glycoprotein | 0.021 | |
| Ugt2b | UDP glycosyltransferase 2 family, polypeptide B | 0.020 | |
| Cubn | cubilin (intrinsic factor-cobalamin receptor) | 0.020 | |
| Atxn1 | ataxin 1 | 0.020 | |
| Eci2 | enoyl-Coenzyme A delta isomerase 2 | 0.020 | |
| Crisp1 | cysteine-rich secretory protein 1 | 0.020 | |
| Gpr150 | G protein-coupled receptor 150 | 0.020 | |
| Hao2 | hydroxyacid oxidase 2 (long chain) | 0.019 | |
| Mybpc1 | myosin binding protein C, slow type | 0.019 | |
| Cacnb4 | calcium channel, voltage-dependent, beta 4 subunit | 0.018 | |
| Olr416 | olfactory receptor 416 | 0.018 | |
| Cyp2d2 | cytochrome P450, family 2, subfamily d, polypeptide 2 | 0.018 | |
| Ocm | oncomodulin | 0.018 | |
| Sdha | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.017 | |
| Pxmp2 | peroxisomal membrane protein 2 | 0.017 | |
| Csrp3 | cysteine and glycine-rich protein 3 | 0.017 | |
| Drd1a | dopamine receptor D1A | 0.017 | |
| ND4 | NADH dehydrogenase subunit 4 | 0.017 | |
| Cmbl | carboxymethylenebutenolidase homolog (Pseudomonas) | 0.017 | |
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.017 | |
| Gsta4 | glutathione S-transferase alpha 4 | 0.017 | |
| Fut1 | fucosyltransferase 1 | 0.017 | |
| Vip | vasoactive intestinal peptide | 0.017 | |
| Svs5 | seminal vesicle secretory protein 5 | 0.016 | |
| Cgm4 | carcinoembryonic antigen gene family 4 | 0.016 | |
| Prl3c1 | Prolactin family 3, subfamily c, member 1 | 0.016 | |
| Odf1 | outer dense fiber of sperm tails 1 | 0.016 | |
| Chrna10 | cholinergic receptor, nicotinic, alpha 10 | 0.016 | |
| Ppard | peroxisome proliferator-activated receptor delta | 0.016 | |
| Tacr2 | tachykinin receptor 2 | 0.016 | |
| Ucp1 | uncoupling protein 1 (mitochondrial, proton carrier) | 0.016 | |
| Lalba | lactalbumin, alpha | 0.016 | |
| Cyp17a1 | cytochrome P450, family 17, subfamily a, polypeptide 1 | 0.015 | |
| Npffr2 | neuropeptide FF receptor 2 | 0.015 | |
| Atp2c2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.015 | |
| Adk | adenosine kinase | 0.015 | |
| Grik3 | glutamate receptor, ionotropic, kainate 3 | 0.014 | |
| Akp3 | alkaline phosphatase 3, intestine, not Mn requiring | 0.014 | |
| Cd80 | Cd80 molecule | 0.014 | |
| Aldh6a1 | aldehyde dehydrogenase 6 family, member A1 | 0.014 | |
| Mettl7b | methyltransferase like 7B | 0.014 | |
| Pdhb | pyruvate dehydrogenase (lipoamide) beta | 0.014 | |
| Vcsa2 | variable coding sequence A2 | 0.014 | |
| Zadh2 | zinc binding alcohol dehydrogenase, domain containing 2 | 0.013 | |
| Gcm1 | glial cells missing homolog 1 (Drosophila) | 0.013 | |
| Mamdc4 | MAM domain containing 4 | 0.013 | |
| Omp | olfactory marker protein | 0.013 | |
| Gpx2 | glutathione peroxidase 2 | 0.013 | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.013 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.013 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.938 | |
| Mc2r | melanocortin 2 receptor | 0.502 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.222 | |
| Mep1a | meprin 1 alpha | 0.159 | |
| Afm | afamin | 0.124 | |
| Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble | 0.120 | |
| Akr1c21 | aldo-keto reductase family 1, member C21 | 0.112 | |
| Cyp2c50 | cytochrome P450, family 2, subfamily c, polypeptide 50 | 0.099 | |
| Acadm | acyl-Coenzyme A dehydrogenase, medium chain | 0.094 | |
| Star | steroidogenic acute regulatory protein | 0.093 | |
| Aqp8 | aquaporin 8 | 0.090 | |
| Cat | catalase | 0.088 | |
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.083 | |
| Akr1c6 | aldo-keto reductase family 1, member C6 | 0.081 | |
| Aadac | arylacetamide deacetylase (esterase) | 0.076 | |
| Hsdl2 | hydroxysteroid dehydrogenase like 2 | 0.076 | |
| Slc12a1 | solute carrier family 12, member 1 | 0.061 | |
| 4931406C07Rik | RIKEN cDNA 4931406C07 gene | 0.057 | |
| Chpt1 | choline phosphotransferase 1 | 0.054 | |
| Hao2 | hydroxyacid oxidase 2 | 0.053 | |
| Hoxa10 | homeobox A10 | 0.051 | |
| Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | 0.050 | |
| Otc | ornithine transcarbamylase | 0.046 | |
| Hgd | homogentisate 1, 2-dioxygenase | 0.046 | |
| Hsd17b4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.044 | |
| Adh4 | alcohol dehydrogenase 4 (class II), pi polypeptide | 0.041 | |
| Cyp2a12 | cytochrome P450, family 2, subfamily a, polypeptide 12 | 0.039 | |
| Rdh7 | retinol dehydrogenase 7 | 0.035 | |
| Pik3c2g | phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide | 0.035 | |
| Aldh6a1 | aldehyde dehydrogenase family 6, subfamily A1 | 0.035 | |
| Phyh | phytanoyl-CoA hydroxylase | 0.034 | |
| Abcc2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | 0.033 | |
| Nr1i3 | nuclear receptor subfamily 1, group I, member 3 | 0.032 | |
| Lypla1 | lysophospholipase 1 | 0.031 | |
| Serpina6 | serine (or cysteine) peptidase inhibitor, clade A, member 6 | 0.031 | |
| Fbp1 | fructose bisphosphatase 1 | 0.029 | |
| G6pc | glucose-6-phosphatase, catalytic | 0.029 | |
| Hsd3b6 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 | 0.029 | |
| Cyp7a1 | cytochrome P450, family 7, subfamily a, polypeptide 1 | 0.027 | |
| Hpd | 4-hydroxyphenylpyruvic acid dioxygenase | 0.026 | |
| Apoh | apolipoprotein H | 0.026 | |
| C9 | complement component 9 | 0.026 | |
| Hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 0.025 | |
| Cps1 | carbamoyl-phosphate synthetase 1 | 0.025 | |
| Timd2 | T-cell immunoglobulin and mucin domain containing 2 | 0.024 | |
| Prl7a1 | prolactin family 7, subfamily a, member 1 | 0.024 | |
| F13b | coagulation factor XIII, beta subunit | 0.024 | |
| Uox | urate oxidase | 0.023 | |
| Cyp2c39 | cytochrome P450, family 2, subfamily c, polypeptide 39 | 0.023 | |
| Cyp2c29 | cytochrome P450, family 2, subfamily c, polypeptide 29 | 0.023 | |
| Upp2 | uridine phosphorylase 2 | 0.023 | |
| Hsd3b5 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 | 0.022 | |
| Sult1b1 | sulfotransferase family 1B, member 1 | 0.021 | |
| Hadhb | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 0.021 | |
| Acsm3 | acyl-CoA synthetase medium-chain family member 3 | 0.020 | |
| Hadh | hydroxyacyl-Coenzyme A dehydrogenase | 0.019 | |
| Nr5a2 | nuclear receptor subfamily 5, group A, member 2 | 0.019 | |
| Sva | seminal vesicle antigen | 0.018 | |
| Cyp2j5 | cytochrome P450, family 2, subfamily j, polypeptide 5 | 0.018 | |
| Car1 | carbonic anhydrase 1 | 0.017 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.017 | |
| Cyp2d9 | cytochrome P450, family 2, subfamily d, polypeptide 9 | 0.017 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.017 | |
| Muc13 | mucin 13, epithelial transmembrane | 0.017 | |
| BC013529 | cDNA sequence BC013529 | 0.017 | |
| G6pc2 | glucose-6-phosphatase, catalytic, 2 | 0.017 | |
| Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2 | 0.017 | |
| Ces1g | carboxylesterase 1G | 0.016 | |
| Mbl2 | mannose-binding lectin (protein C) 2 | 0.016 | |
| Ces3a | carboxylesterase 3A | 0.016 | |
| Ar | androgen receptor | 0.016 | |
| Slc17a1 | solute carrier family 17 (sodium phosphate), member 1 | 0.015 | |
| Necap2 | NECAP endocytosis associated 2 | 0.015 | |
| Cyp2d26 | cytochrome P450, family 2, subfamily d, polypeptide 26 | 0.015 | |
| Tnp1 | transition protein 1 | 0.015 | |
| Dram2 | VDNA-damage regulated autophagy modulator 2 | 0.015 | |
| Clrn3 | clarin 3 | 0.015 | |
| Tdo2 | tryptophan 2,3-dioxygenase | 0.015 | |
| 1700074P13Rik | RIKEN cDNA 1700074P13 gene | 0.015 | |
| Acat1 | acetyl-Coenzyme A acetyltransferase 1 | 0.014 | |
| Ugt2b1 | UDP glucuronosyltransferase 2 family, polypeptide B1 | 0.014 | |
| Pah | phenylalanine hydroxylase | 0.014 | |
| Ugt2b5 | UDP glucuronosyltransferase 2 family, polypeptide B5 | 0.014 | |
| Acad11 | acyl-Coenzyme A dehydrogenase family, member 11 | 0.014 | |
| Apob | apolipoprotein B | 0.014 | |
| Vmn1r51 | vomeronasal 1 receptor 51 | 0.014 | |
| Slc25a20 | solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 | 0.014 | |
| Rab9 | RAB9, member RAS oncogene family | 0.014 | |
| Slc26a1 | solute carrier family 26 (sulfate transporter), member 1 | 0.014 | |
| Serpina5 | serine (or cysteine) peptidase inhibitor, clade A, member 5 | 0.014 | |
| F9 | coagulation factor IX | 0.014 | |
| Ugt2b34 | UDP glucuronosyltransferase 2 family, polypeptide B34 | 0.013 | |
| Syap1 | synapse associated protein 1 | 0.013 | |
| Hrsp12 | heat-responsive protein 12 | 0.013 | |
| Alb | albumin | 0.013 | |
| Cst8 | cystatin 8 (cystatin-related epididymal spermatogenic) | 0.013 | |
| Klkb1 | kallikrein B, plasma 1 | 0.013 | |
| Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.013 | |
| Csn1s2a | casein alpha s2-like A | 0.013 | |
| Cyp2c54 | cytochrome P450, family 2, subfamily c, polypeptide 54 | 0.013 |