|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.995
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.990
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.984
|
Human Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.983
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.983
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.979
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.979
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.971
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.960
|
Fly |
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.957
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.957
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.947
|
Mouse |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.946
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.945
|
Fly |
|
|
cell activation
|
GO:0001775 |
213 |
0.941
|
Human Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.941
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.938
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.933
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.929
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.928
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.928
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.924
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.923
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.922
|
Fly |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.918
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.911
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.909
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.907
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.906
|
Fly |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.899
|
Mouse Fly |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.899
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.898
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.884
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.882
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.881
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.879
|
Fly |
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.876
|
Mouse |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.874
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.871
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.869
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.868
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.868
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.860
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.849
|
Human |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.845
|
|
|
|
granulocyte migration
|
GO:0097530 |
40 |
0.842
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.829
|
Human Mouse Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.827
|
Human Mouse Fly |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.824
|
Human |
|
|
neuron projection development
|
GO:0031175 |
106 |
0.815
|
Fly |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.812
|
Human |
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
5 |
0.801
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.783
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.783
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.774
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.758
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.752
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.743
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.741
|
Human Mouse Fly |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.727
|
Human Mouse Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.724
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.719
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.715
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.713
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.712
|
Mouse |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.711
|
Human Mouse Fly |
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
10 |
0.708
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.702
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.698
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.695
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.677
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.677
|
Mouse Fly |
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.672
|
Mouse |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.669
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.658
|
Mouse |
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.652
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.650
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.639
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.638
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.634
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.619
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.617
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.615
|
|
|
|
negative regulation of calcium mediated signaling
|
GO:0050849 |
4 |
0.614
|
|
|
|
t cell selection
|
GO:0045058 |
4 |
0.613
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.601
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.593
|
Human Mouse Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.590
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.584
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.582
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.579
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.577
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.575
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.564
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.564
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.563
|
Human Mouse Fly |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.563
|
Human Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.560
|
Mouse Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.553
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.548
|
|
|
|
regulation of collagen catabolic process
|
GO:0010710 |
3 |
0.542
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.536
|
Human |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.536
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.531
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.523
|
Human Mouse Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.523
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.513
|
Human Mouse Fly |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.506
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.506
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.505
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.503
|
Fly |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.502
|
Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.502
|
Human Mouse Fly |
|
|
platelet activation
|
GO:0030168 |
44 |
0.501
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.498
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.489
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.483
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.480
|
Mouse |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.472
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.471
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.469
|
Human |
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.469
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.461
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.460
|
Human Mouse Fly |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.447
|
Human Mouse Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.442
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.440
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.438
|
Fly |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.429
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.427
|
Mouse Fly |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.423
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.422
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.419
|
Human Mouse Fly |
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.419
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.412
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.402
|
Fly |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.401
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.394
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.391
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.391
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.381
|
Mouse Fly |
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.379
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.377
|
Fly |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.370
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.364
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.363
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.359
|
Mouse |
|
|
positive thymic t cell selection
|
GO:0045059 |
1 |
0.359
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.354
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.350
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.340
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.338
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.338
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.336
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.334
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.332
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.328
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.327
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.322
|
Human |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.316
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.314
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.312
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.312
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.312
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.305
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.301
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.300
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.299
|
|
|
|
macrophage activation involved in immune response
|
GO:0002281 |
1 |
0.296
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.295
|
Human Mouse Fly |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.293
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.292
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.292
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.290
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.276
|
Human Mouse Fly |
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.273
|
Fly |
|
|
cation transport
|
GO:0006812 |
331 |
0.266
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.266
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.266
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.265
|
Mouse Fly |
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.265
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.264
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.264
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.262
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.256
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.253
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.251
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.250
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.246
|
Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.244
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.243
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.242
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.240
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.239
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.239
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.234
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.229
|
Fly |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.225
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.224
|
Human |
|
|
endocytosis
|
GO:0006897 |
159 |
0.224
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.223
|
Human Mouse Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.221
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.220
|
Human |
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.220
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.219
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.219
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.216
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.215
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.212
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.209
|
Human Mouse Fly |
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.200
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.199
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.198
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.195
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.192
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.189
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.186
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.186
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.186
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.182
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.182
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.181
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.179
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.179
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.179
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
37 |
0.179
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.177
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.177
|
Mouse Fly |
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.177
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.175
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.174
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
15 |
0.173
|
|
|
|
regulation of sequestering of calcium ion
|
GO:0051282 |
41 |
0.173
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.172
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.171
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.167
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.167
|
Fly |
|
|
regulation of stress fiber assembly
|
GO:0051492 |
32 |
0.162
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.162
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.161
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.159
|
Human Mouse Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.158
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.158
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.154
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.153
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.152
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.152
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.151
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.151
|
Human |
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.149
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.145
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.145
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.143
|
Human Mouse Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.143
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.141
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.138
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.137
|
|
|
|
thymic t cell selection
|
GO:0045061 |
2 |
0.136
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.136
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.133
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.132
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
5 |
0.131
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.131
|
Fly |
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.130
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.130
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.129
|
Worm |
|
|
neutrophil migration
|
GO:1990266 |
25 |
0.127
|
Mouse |
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.127
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.125
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.124
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.124
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.124
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.121
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.119
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.119
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.118
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.117
|
Mouse Fly |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.117
|
Human Mouse Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.117
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.114
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.114
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.112
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.111
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.110
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.109
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.109
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.108
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.108
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.107
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.107
|
|
|
|
regulation of neutrophil activation
|
GO:1902563 |
1 |
0.106
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.105
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.104
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.104
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.102
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.102
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.102
|
|
|
|
neutrophil mediated immunity
|
GO:0002446 |
4 |
0.101
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.101
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.101
|
Worm |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.101
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.100
|
Human |
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.100
|
Mouse |
|
|
response to hormone
|
GO:0009725 |
175 |
0.097
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.096
|
Fly |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.095
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
37 |
0.095
|
Mouse |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.093
|
|
|
|
positive regulation of cell migration involved in sprouting angiogenesis
|
GO:0090050 |
3 |
0.093
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.092
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.091
|
Mouse Fly |
|
|
regulation of system process
|
GO:0044057 |
101 |
0.091
|
|
|
|
system process
|
GO:0003008 |
349 |
0.091
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.091
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.090
|
|
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.090
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.090
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.089
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.088
|
|
|
|
growth
|
GO:0040007 |
202 |
0.088
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
41 |
0.087
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.086
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.086
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.086
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.085
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.084
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.083
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.082
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.082
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.082
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.081
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.080
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.080
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.079
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.079
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.079
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.079
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.078
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.078
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.077
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.076
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.076
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.076
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.075
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.075
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.074
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.074
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.074
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.073
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.072
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.072
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.072
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
24 |
0.072
|
Mouse |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.072
|
Mouse |
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.071
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.071
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.071
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.070
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
7 |
0.069
|
|
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.066
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.066
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.066
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.066
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.065
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.065
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.064
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.064
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.064
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.063
|
Human Mouse Fly |
|
|
memory
|
GO:0007613 |
3 |
0.063
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.063
|
Human Mouse Fly |
|
|
natural killer cell proliferation
|
GO:0001787 |
4 |
0.062
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.062
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.061
|
Fly |
|
|
regulation of calcium ion transport into cytosol
|
GO:0010522 |
33 |
0.060
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.060
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.060
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.060
|
Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.059
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
19 |
0.058
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.058
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.057
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.057
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.057
|
Human |
|
|
secretion
|
GO:0046903 |
254 |
0.057
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.056
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.056
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.056
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.055
|
Fly |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.055
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.055
|
Human Mouse Fly |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.055
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.055
|
|
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.054
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.054
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.053
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
4 |
0.053
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.053
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.053
|
|
|
|
negative regulation of b cell receptor signaling pathway
|
GO:0050859 |
2 |
0.053
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.053
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.052
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.052
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.052
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.052
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.052
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.052
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.052
|
Human Mouse Fly |
|
|
response to insulin
|
GO:0032868 |
45 |
0.051
|
|
|
|
regulation of b cell receptor signaling pathway
|
GO:0050855 |
4 |
0.051
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.051
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.050
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
39 |
0.050
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.050
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.050
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.050
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.049
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.049
|
|
|
|
zinc ion homeostasis
|
GO:0055069 |
12 |
0.048
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.047
|
Human |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.047
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.047
|
Mouse Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.047
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.047
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.046
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.046
|
|
|
|
positive regulation of cell adhesion mediated by integrin
|
GO:0033630 |
9 |
0.046
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.046
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.045
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.045
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.045
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.045
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
4 |
0.045
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.045
|
|
|
|
regulation of insulin secretion
|
GO:0050796 |
33 |
0.044
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.044
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.044
|
Fly |
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.043
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.043
|
|
|
|
monosaccharide transport
|
GO:0015749 |
32 |
0.043
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.043
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.042
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.042
|
|
|
|
platelet degranulation
|
GO:0002576 |
2 |
0.042
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
10 |
0.042
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.042
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.041
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.041
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
20 |
0.041
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.040
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.040
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.040
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.040
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.040
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.039
|
Worm |
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.039
|
Human |
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.039
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.039
|
|
|
|
regulation of phagocytosis engulfment
|
GO:0060099 |
2 |
0.039
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.039
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.039
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.039
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
10 |
0.038
|
|
|
|
cellular extravasation
|
GO:0045123 |
21 |
0.038
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.038
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.038
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.038
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.038
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.038
|
|
|
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.037
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.037
|
|
|
|
sensory perception of chemical stimulus
|
GO:0007606 |
38 |
0.036
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.036
|
Fly |
|
|
positive regulation of phagocytosis
|
GO:0050766 |
15 |
0.036
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.036
|
|
|
|
negative regulation of protein tyrosine kinase activity
|
GO:0061099 |
13 |
0.036
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
21 |
0.036
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.035
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.035
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.035
|
|
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.035
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.035
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.035
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.035
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.034
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.034
|
|
