IMP
Process View
negative regulation of protein tyrosine kinase activity
Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein tyrosine kinase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.815 | Human | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.651 | Human | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.549 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.360 | Human | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.225 | ||
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.162 | ||
| BLNK | B-cell linker | 0.152 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.152 | ||
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.122 | Human | |
| CUL2 | cullin 2 | 0.104 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.091 | ||
| EGFR | epidermal growth factor receptor | 0.085 | ||
| NCK1 | NCK adaptor protein 1 | 0.046 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.041 | ||
| ZNF496 | zinc finger protein 496 | 0.038 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.036 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.036 | ||
| TNS4 | tensin 4 | 0.036 | ||
| GRB2 | growth factor receptor-bound protein 2 | 0.034 | Fly | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.033 | Human Fly | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.031 | ||
| ITK | IL2-inducible T-cell kinase | 0.031 | ||
| HCK | hemopoietic cell kinase | 0.031 | Human | |
| PSEN1 | presenilin 1 | 0.026 | Mouse | |
| MUC1 | mucin 1, cell surface associated | 0.026 | ||
| EPOR | erythropoietin receptor | 0.022 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.022 | ||
| SPRR2A | small proline-rich protein 2A | 0.019 | ||
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.019 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.018 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.017 | ||
| SNX9 | sorting nexin 9 | 0.017 | ||
| GRB7 | growth factor receptor-bound protein 7 | 0.017 | ||
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.017 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.016 | ||
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.016 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.015 | Human | |
| FLNB | filamin B, beta | 0.015 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.015 | Human | |
| SFN | stratifin | 0.014 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.013 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.013 | ||
| JAK2 | Janus kinase 2 | 0.013 | ||
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.013 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.011 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.011 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.011 | ||
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.011 | ||
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.011 | ||
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.010 | Mouse | |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.010 |