IMP
Process View
positive regulation of alpha beta t cell differentiation
Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of alpha beta t cell differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| LCK | lymphocyte-specific protein tyrosine kinase | 0.977 | ||
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.861 | ||
| CD247 | CD247 molecule | 0.819 | ||
| LIN9 | lin-9 homolog (C. elegans) | 0.772 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.682 | ||
| RXRA | retinoid X receptor, alpha | 0.582 | ||
| LAT | linker for activation of T cells | 0.459 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.303 | ||
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.286 | ||
| MED25 | mediator complex subunit 25 | 0.230 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.218 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.214 | ||
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.207 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.195 | ||
| IL4R | interleukin 4 receptor | 0.179 | Mouse | |
| RBMX2 | RNA binding motif protein, X-linked 2 | 0.179 | ||
| CTBP1 | C-terminal binding protein 1 | 0.173 | ||
| IL4 | interleukin 4 | 0.156 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.134 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.134 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.129 | ||
| IL6R | interleukin 6 receptor | 0.109 | ||
| RXRB | retinoid X receptor, beta | 0.105 | ||
| SYK | spleen tyrosine kinase | 0.104 | Mouse | |
| RARA | retinoic acid receptor, alpha | 0.101 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.086 | ||
| CCDC115 | coiled-coil domain containing 115 | 0.086 | ||
| KLHL24 | kelch-like 24 (Drosophila) | 0.082 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.080 | ||
| UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.079 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.074 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.071 | ||
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.067 | ||
| PML | promyelocytic leukemia | 0.065 | ||
| ENG | endoglin | 0.063 | ||
| IKZF3 | IKAROS family zinc finger 3 (Aiolos) | 0.062 | ||
| ZHX1 | zinc fingers and homeoboxes 1 | 0.060 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.060 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.057 | ||
| SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.057 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.054 | ||
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.051 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.050 | ||
| CSNK1G1 | casein kinase 1, gamma 1 | 0.048 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.047 | Mouse | |
| C5orf41 | chromosome 5 open reading frame 41 | 0.046 | ||
| RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.042 | ||
| PRKCQ | protein kinase C, theta | 0.040 | ||
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 | 0.040 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.039 | ||
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.037 | ||
| SH2D2A | SH2 domain containing 2A | 0.037 | ||
| SLA | Src-like-adaptor | 0.036 | ||
| LIN54 | lin-54 homolog (C. elegans) | 0.036 | ||
| IL7R | interleukin 7 receptor | 0.034 | ||
| NLK | nemo-like kinase | 0.033 | ||
| RUNX1 | runt-related transcription factor 1 | 0.033 | ||
| PARD6G | par-6 partitioning defective 6 homolog gamma (C. elegans) | 0.032 | ||
| CHERP | calcium homeostasis endoplasmic reticulum protein | 0.032 | ||
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.031 | Mouse | |
| FSTL1 | follistatin-like 1 | 0.031 | ||
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.031 | ||
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.031 | ||
| IL8 | interleukin 8 | 0.031 | ||
| NUMB | numb homolog (Drosophila) | 0.030 | ||
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.030 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.029 | ||
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.029 | ||
| HDAC9 | histone deacetylase 9 | 0.029 | ||
| PARD6B | par-6 partitioning defective 6 homolog beta (C. elegans) | 0.027 | ||
| CREBBP | CREB binding protein | 0.027 | ||
| SH2D1A | SH2 domain containing 1A | 0.027 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.026 | ||
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.026 | ||
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.025 | ||
| CD38 | CD38 molecule | 0.024 | ||
| MAPK7 | mitogen-activated protein kinase 7 | 0.024 | ||
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.024 | ||
| STK36 | serine/threonine kinase 36 | 0.023 | ||
| ZNF71 | zinc finger protein 71 | 0.023 | ||
| FAM101B | family with sequence similarity 101, member B | 0.023 | ||
| NCOR1 | nuclear receptor corepressor 1 | 0.023 | ||
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.022 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.022 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.022 | ||
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | 0.022 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.022 | ||
| IKZF4 | IKAROS family zinc finger 4 (Eos) | 0.021 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.021 | ||
| THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 0.021 | Human | |
| NMT2 | N-myristoyltransferase 2 | 0.020 | ||
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.020 | ||
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.020 | ||
| PARD6A | par-6 partitioning defective 6 homolog alpha (C. elegans) | 0.020 | ||
| RXRG | retinoid X receptor, gamma | 0.020 | ||
| STK4 | serine/threonine kinase 4 | 0.020 | ||
| TGFBR3 | transforming growth factor, beta receptor III | 0.020 | ||
| CD48 | CD48 molecule | 0.019 | ||
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.019 | ||
| GLA | galactosidase, alpha | 0.018 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.018 | ||
| IL2RB | interleukin 2 receptor, beta | 0.018 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.018 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.018 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.018 | ||
| LIN52 | lin-52 homolog (C. elegans) | 0.017 | ||
| ARHGAP5 | Rho GTPase activating protein 5 | 0.017 | ||
| IL1B | interleukin 1, beta | 0.017 | ||
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | 0.017 | ||
| BUD13 | BUD13 homolog (S. cerevisiae) | 0.017 | ||
| CD37 | CD37 molecule | 0.017 | ||
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.017 | ||
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.016 | ||
| BANP | BTG3 associated nuclear protein | 0.016 | ||
| EPOR | erythropoietin receptor | 0.016 | ||
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.016 | ||
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.015 | ||
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.015 | ||
| FAM64A | family with sequence similarity 64, member A | 0.015 | ||
| GPSM3 | G-protein signaling modulator 3 | 0.015 | ||
| JAK3 | Janus kinase 3 | 0.015 | ||
| SH2D3C | SH2 domain containing 3C | 0.015 | ||
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.014 | ||
| NRP1 | neuropilin 1 | 0.014 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.014 | ||
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.014 | ||
| CD28 | CD28 molecule | 0.014 | ||
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.014 | ||
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.014 | ||
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.014 | ||
| SORBS3 | sorbin and SH3 domain containing 3 | 0.014 | ||
| BCL6 | B-cell CLL/lymphoma 6 | 0.014 | ||
| CD33 | CD33 molecule | 0.014 | ||
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) | 0.014 | ||
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | 0.014 | ||
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.013 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.013 | ||
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 0.013 | ||
| PGR | progesterone receptor | 0.013 | ||
| SELL | selectin L | 0.013 | ||
| PDGFC | platelet derived growth factor C | 0.013 | ||
| CCND3 | cyclin D3 | 0.013 | ||
| CD2 | CD2 molecule | 0.013 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.013 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.013 | ||
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.013 | ||
| MED1 | mediator complex subunit 1 | 0.013 | ||
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.013 | ||
| IL7 | interleukin 7 | 0.013 | ||
| PGAM5 | phosphoglycerate mutase family member 5 | 0.012 | ||
| CD53 | CD53 molecule | 0.012 | ||
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.012 | ||
| HDAC11 | histone deacetylase 11 | 0.012 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.012 | ||
| BID | BH3 interacting domain death agonist | 0.012 | ||
| GSTM4 | glutathione S-transferase mu 4 | 0.012 | ||
| CH25H | cholesterol 25-hydroxylase | 0.012 | ||
| SELE | selectin E | 0.012 | ||
| CHMP7 | CHMP family, member 7 | 0.012 | ||
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.012 | ||
| CRABP2 | cellular retinoic acid binding protein 2 | 0.012 | ||
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.012 | ||
| LNX1 | ligand of numb-protein X 1 | 0.012 | ||
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.012 | ||
| PRKCI | protein kinase C, iota | 0.012 | ||
| IL12A | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) | 0.012 | ||
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.012 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.012 | ||
| PCBP2 | poly(rC) binding protein 2 | 0.012 | ||
| DLG5 | discs, large homolog 5 (Drosophila) | 0.012 | ||
| CMIP | c-Maf-inducing protein | 0.012 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.012 | ||
| RHOH | ras homolog gene family, member H | 0.012 | ||
| ZNF576 | zinc finger protein 576 | 0.012 | ||
| SPI1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.012 | ||
| CCNE1 | cyclin E1 | 0.012 | ||
| HRH1 | histamine receptor H1 | 0.012 | ||
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.012 | ||
| FAIM3 | Fas apoptotic inhibitory molecule 3 | 0.011 | ||
| CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.011 | ||
| SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.011 | ||
| CTSW | cathepsin W | 0.011 | ||
| APP | amyloid beta (A4) precursor protein | 0.011 | ||
| IL32 | interleukin 32 | 0.011 | ||
| PLEK | pleckstrin | 0.011 | ||
| CD22 | CD22 molecule | 0.011 | ||
| CD7 | CD7 molecule | 0.011 | ||
| NR1D1 | nuclear receptor subfamily 1, group D, member 1 | 0.011 | Human | |
| ACVR1 | activin A receptor, type I | 0.011 | ||
| FAM65B | family with sequence similarity 65, member B | 0.011 | ||
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.011 | ||
| ADAMTS4 | ADAM metallopeptidase with thrombospondin type 1 motif, 4 | 0.011 | ||
| KIF21B | kinesin family member 21B | 0.011 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.011 | ||
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.011 | ||
| GIMAP1 | GTPase, IMAP family member 1 | 0.011 | ||
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.011 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.011 | ||
| PPIF | peptidylprolyl isomerase F | 0.011 | ||
| THRB | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | 0.011 | Human | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.011 | ||
| LRMP | lymphoid-restricted membrane protein | 0.011 | ||
| GATA3 | GATA binding protein 3 | 0.011 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.011 | ||
| NRP2 | neuropilin 2 | 0.011 | ||
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 0.011 | ||
| SPAG9 | sperm associated antigen 9 | 0.011 | ||
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.011 | ||
| CD69 | CD69 molecule | 0.011 | ||
| PRKD2 | protein kinase D2 | 0.011 | ||
| KIAA0100 | KIAA0100 | 0.011 | ||
| CD27 | CD27 molecule | 0.011 | ||
| IL24 | interleukin 24 | 0.011 | ||
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.011 | ||
| DLG1 | discs, large homolog 1 (Drosophila) | 0.011 | ||
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.011 | ||
| IL21R | interleukin 21 receptor | 0.011 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.011 | ||
| DIAPH1 | diaphanous homolog 1 (Drosophila) | 0.011 | ||
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.011 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.010 | ||
| DENND1C | DENN/MADD domain containing 1C | 0.010 | ||
| SETDB1 | SET domain, bifurcated 1 | 0.010 | ||
| CLTC | clathrin, heavy chain (Hc) | 0.010 | ||
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.010 | ||
| RGS16 | regulator of G-protein signaling 16 | 0.010 | ||
| AKR1C3 | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 0.010 | ||
| AR | androgen receptor | 0.010 | ||
| BLNK | B-cell linker | 0.010 | ||
| CD4 | CD4 molecule | 0.010 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.010 | ||
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.010 | ||
| GATA2 | GATA binding protein 2 | 0.010 | ||
| ITK | IL2-inducible T-cell kinase | 0.010 | ||
| CSNK1G2 | casein kinase 1, gamma 2 | 0.010 | ||
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 0.010 | ||
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.010 | ||
| GRPEL1 | GrpE-like 1, mitochondrial (E. coli) | 0.010 | ||
| SIPA1 | signal-induced proliferation-associated 1 | 0.010 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.010 | ||
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.010 | ||
| C9orf25 | chromosome 9 open reading frame 25 | 0.010 | ||
| PLAC8 | placenta-specific 8 | 0.010 | ||
| E2F3 | E2F transcription factor 3 | 0.010 | ||
| RUNX3 | runt-related transcription factor 3 | 0.010 | ||
| LMTK3 | lemur tyrosine kinase 3 | 0.010 | ||
| GSTM5 | glutathione S-transferase mu 5 | 0.010 | ||
| USPL1 | ubiquitin specific peptidase like 1 | 0.010 | ||
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 0.010 | ||
| IL18R1 | interleukin 18 receptor 1 | 0.010 | ||
| C19orf6 | chromosome 19 open reading frame 6 | 0.010 | ||
| NPAS2 | neuronal PAS domain protein 2 | 0.010 |