IMP

Process View

Homo sapiens

19 genes annotated in human

regulation of lipid kinase activity

Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of lipid kinase activity"

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Name	Description	Probability	Func Analog Organism
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	1.000	Human
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	1.000	Human
FGF1	fibroblast growth factor 1 (acidic)	0.999	Human
FGFR2	fibroblast growth factor receptor 2	0.999	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.999	Human Rat
EGFR	epidermal growth factor receptor	0.996	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.996	Human
PLCG1	phospholipase C, gamma 1	0.995
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.994	Rat Fly
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.992
GRB7	growth factor receptor-bound protein 7	0.992
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.981
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.977
FGFR1	fibroblast growth factor receptor 1	0.973	Human
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.962	Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.954	Mouse
CCR5	chemokine (C-C motif) receptor 5	0.943
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.916
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.915	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.909
CCL4	chemokine (C-C motif) ligand 4	0.908	Human
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.841
NRP1	neuropilin 1	0.812
ANGPT2	angiopoietin 2	0.806
VEGFA	vascular endothelial growth factor A	0.799	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.791
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.750
SYK	spleen tyrosine kinase	0.746
GRB2	growth factor receptor-bound protein 2	0.650
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.521
SPRR2A	small proline-rich protein 2A	0.501
CXCL9	chemokine (C-X-C motif) ligand 9	0.471
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.470	Human
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.464
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.417
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.395
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.375
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.366	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.357
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.279
MED25	mediator complex subunit 25	0.277
PTK6	PTK6 protein tyrosine kinase 6	0.270	Human
HCK	hemopoietic cell kinase	0.266	Human
CCR7	chemokine (C-C motif) receptor 7	0.250
CCL19	chemokine (C-C motif) ligand 19	0.248
MED28	mediator complex subunit 28	0.227
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.225	Mouse Rat Fly
GRB10	growth factor receptor-bound protein 10	0.205
PDGFA	platelet-derived growth factor alpha polypeptide	0.200	Human
BLNK	B-cell linker	0.198
CCL5	chemokine (C-C motif) ligand 5	0.185	Human
FGF10	fibroblast growth factor 10	0.179	Human
CCL13	chemokine (C-C motif) ligand 13	0.166	Human
IL8	interleukin 8	0.162
ZNF746	zinc finger protein 746	0.158
VAV3	vav 3 guanine nucleotide exchange factor	0.147	Mouse
BCAR1	breast cancer anti-estrogen resistance 1	0.145
GAB1	GRB2-associated binding protein 1	0.143
ITK	IL2-inducible T-cell kinase	0.129
BCL2	B-cell CLL/lymphoma 2	0.128
TGFB3	transforming growth factor, beta 3	0.126
CXCL11	chemokine (C-X-C motif) ligand 11	0.124
CCL22	chemokine (C-C motif) ligand 22	0.120	Human
ANGPT1	angiopoietin 1	0.118
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.104
CD81	CD81 molecule	0.102
CCL8	chemokine (C-C motif) ligand 8	0.094	Human
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.089
ENG	endoglin	0.088
DPP4	dipeptidyl-peptidase 4	0.086
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.085
TNS3	tensin 3	0.084
SLA	Src-like-adaptor	0.084
IDE	insulin-degrading enzyme	0.083
IL7R	interleukin 7 receptor	0.081
RB1	retinoblastoma 1	0.080
RXRA	retinoid X receptor, alpha	0.077
CXCL13	chemokine (C-X-C motif) ligand 13	0.076
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.074
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.073
MATK	megakaryocyte-associated tyrosine kinase	0.071
VCAM1	vascular cell adhesion molecule 1	0.070
VAV1	vav 1 guanine nucleotide exchange factor	0.070
CCL2	chemokine (C-C motif) ligand 2	0.069	Human
IGF1R	insulin-like growth factor 1 receptor	0.068
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.068
CCL3	chemokine (C-C motif) ligand 3	0.067	Human
NRG1	neuregulin 1	0.067
CD63	CD63 molecule	0.064
FGF2	fibroblast growth factor 2 (basic)	0.061
GAS7	growth arrest-specific 7	0.058
ETF1	eukaryotic translation termination factor 1	0.058
CD9	CD9 molecule	0.057	Human
PTPRB	protein tyrosine phosphatase, receptor type, B	0.057
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.056
INSR	insulin receptor	0.056
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.055
PGF	placental growth factor	0.054	Human
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.053
THBS1	thrombospondin 1	0.051
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.049
WIPF1	WAS/WASL interacting protein family, member 1	0.048
KRT8	keratin 8	0.048
CDH5	cadherin 5, type 2 (vascular endothelium)	0.048
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.047
KITLG	KIT ligand	0.047
PTK2	PTK2 protein tyrosine kinase 2	0.045
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.043
IFNG	interferon, gamma	0.041
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.041
UBASH3B	ubiquitin associated and SH3 domain containing B	0.040
E2F4	E2F transcription factor 4, p107/p130-binding	0.039
IL1B	interleukin 1, beta	0.039
TSPAN4	tetraspanin 4	0.039
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.038
VAV2	vav 2 guanine nucleotide exchange factor	0.036	Mouse
FGF7	fibroblast growth factor 7	0.036	Human
RIN1	Ras and Rab interactor 1	0.033
PDCD6IP	programmed cell death 6 interacting protein	0.032
CD79A	CD79a molecule, immunoglobulin-associated alpha	0.031
CTBP1	C-terminal binding protein 1	0.029
FLT4	fms-related tyrosine kinase 4	0.029	Human
CCL11	chemokine (C-C motif) ligand 11	0.029	Human
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.028
IL2RB	interleukin 2 receptor, beta	0.028
CCL7	chemokine (C-C motif) ligand 7	0.028	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.028
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.027
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.027
TNF	tumor necrosis factor	0.026
INO80B	INO80 complex subunit B	0.026
CCR4	chemokine (C-C motif) receptor 4	0.026
CXCL5	chemokine (C-X-C motif) ligand 5	0.025
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.025
TNS4	tensin 4	0.025
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.024	Human
CD83	CD83 molecule	0.023
IL6	interleukin 6 (interferon, beta 2)	0.023
CCR1	chemokine (C-C motif) receptor 1	0.023
CD40	CD40 molecule, TNF receptor superfamily member 5	0.023
IL10	interleukin 10	0.023
FPR3	formyl peptide receptor 3	0.023
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.022
CHN2	chimerin (chimaerin) 2	0.022
PLEK	pleckstrin	0.021
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.021
MUC1	mucin 1, cell surface associated	0.021
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.021
IL2RG	interleukin 2 receptor, gamma	0.020
CD99	CD99 molecule	0.020
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.020
CREBBP	CREB binding protein	0.020
ESR1	estrogen receptor 1	0.019
PDGFC	platelet derived growth factor C	0.019
DLG3	discs, large homolog 3 (Drosophila)	0.018
RXRB	retinoid X receptor, beta	0.018
SELE	selectin E	0.018
FGFR3	fibroblast growth factor receptor 3	0.018
ARRB1	arrestin, beta 1	0.017
SH2D1A	SH2 domain containing 1A	0.017
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.017	Human
SLAMF8	SLAM family member 8	0.017
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.016
NCOA1	nuclear receptor coactivator 1	0.016
OSMR	oncostatin M receptor	0.016
CMIP	c-Maf-inducing protein	0.015
DCN	decorin	0.015
EBI3	Epstein-Barr virus induced 3	0.015
DZIP1	DAZ interacting protein 1	0.015
STAT4	signal transducer and activator of transcription 4	0.015
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.015
SOCS1	suppressor of cytokine signaling 1	0.015
DARC	Duffy blood group, chemokine receptor	0.015
DAB1	disabled homolog 1 (Drosophila)	0.015
XCL1	chemokine (C motif) ligand 1	0.015	Human
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.015
IL18RAP	interleukin 18 receptor accessory protein	0.015
SGOL1	shugoshin-like 1 (S. pombe)	0.014
RGS1	regulator of G-protein signaling 1	0.014
DOK4	docking protein 4	0.014
TOM1L1	target of myb1 (chicken)-like 1	0.014
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.014	Human
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.014
MED1	mediator complex subunit 1	0.014
PTPRA	protein tyrosine phosphatase, receptor type, A	0.014
E2F5	E2F transcription factor 5, p130-binding	0.014
RPL10	ribosomal protein L10	0.013
CD79B	CD79b molecule, immunoglobulin-associated beta	0.013
BTK	Bruton agammaglobulinemia tyrosine kinase	0.013	Human
GNLY	granulysin	0.013
SH3BP2	SH3-domain binding protein 2	0.012
IL1R2	interleukin 1 receptor, type II	0.012
MAP2	microtubule-associated protein 2	0.012
IL21R	interleukin 21 receptor	0.012
WNT2	wingless-type MMTV integration site family member 2	0.012
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.012
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.012
CLEC10A	C-type lectin domain family 10, member A	0.012
SH3RF3	SH3 domain containing ring finger 3	0.012
EIF4E	eukaryotic translation initiation factor 4E	0.012
CD27	CD27 molecule	0.012
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.012
CH25H	cholesterol 25-hydroxylase	0.012
VEGFC	vascular endothelial growth factor C	0.011	Human
SORBS3	sorbin and SH3 domain containing 3	0.011
CSF1	colony stimulating factor 1 (macrophage)	0.011
ITGB7	integrin, beta 7	0.011
TGFB2	transforming growth factor, beta 2	0.011	Human
STC1	stanniocalcin 1	0.011
SRCIN1	SRC kinase signaling inhibitor 1	0.011
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.011
E2F1	E2F transcription factor 1	0.011
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.011
ADAMDEC1	ADAM-like, decysin 1	0.011
INHBA	inhibin, beta A	0.011
LIN54	lin-54 homolog (C. elegans)	0.011
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.011
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.011
C2	complement component 2	0.010
HSPG2	heparan sulfate proteoglycan 2	0.010
IL10RA	interleukin 10 receptor, alpha	0.010
CTGF	connective tissue growth factor	0.010
JAK3	Janus kinase 3	0.010
COL2A1	collagen, type II, alpha 1	0.010
TRO	trophinin	0.010