IMP
Process View
ionotropic glutamate receptor signaling pathway
A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "ionotropic glutamate receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| DLG4 | discs, large homolog 4 (Drosophila) | 1.000 | Rat | |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 1.000 | Human Mouse Rat | |
| KCNA1 | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 1.000 | ||
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 1.000 | Human Mouse Rat | |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 1.000 | ||
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 1.000 | Human Mouse Rat | |
| KCNA4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 1.000 | ||
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 1.000 | ||
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha | 1.000 | ||
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 | 0.999 | ||
| NLGN1 | neuroligin 1 | 0.999 | Mouse Rat | |
| SPRR2A | small proline-rich protein 2A | 0.997 | ||
| CRIPT | cysteine-rich PDZ-binding protein | 0.995 | ||
| APP | amyloid beta (A4) precursor protein | 0.913 | Mouse | |
| GRIP1 | glutamate receptor interacting protein 1 | 0.852 | ||
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | 0.850 | ||
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 | 0.828 | Human Rat | |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta | 0.811 | ||
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.715 | ||
| BAI1 | brain-specific angiogenesis inhibitor 1 | 0.641 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.611 | ||
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.519 | ||
| MATK | megakaryocyte-associated tyrosine kinase | 0.386 | ||
| GRIN2D | glutamate receptor, ionotropic, N-methyl D-aspartate 2D | 0.305 | Human Mouse Rat | |
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.199 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.182 | ||
| GRIK2 | glutamate receptor, ionotropic, kainate 2 | 0.145 | ||
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.135 | ||
| GRIN3B | glutamate receptor, ionotropic, N-methyl-D-aspartate 3B | 0.135 | Human Rat | |
| GRIA4 | glutamate receptor, ionotrophic, AMPA 4 | 0.133 | ||
| MAPT | microtubule-associated protein tau | 0.132 | ||
| DLGAP2 | discs, large (Drosophila) homolog-associated protein 2 | 0.096 | ||
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.093 | ||
| KCND2 | potassium voltage-gated channel, Shal-related subfamily, member 2 | 0.089 | ||
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.078 | ||
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 | 0.075 | ||
| NOS1 | nitric oxide synthase 1 (neuronal) | 0.058 | ||
| DLG3 | discs, large homolog 3 (Drosophila) | 0.052 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.042 | ||
| KCNQ2 | potassium voltage-gated channel, KQT-like subfamily, member 2 | 0.037 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.033 | ||
| KCNJ4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.033 | ||
| DLG2 | discs, large homolog 2 (Drosophila) | 0.031 | ||
| MED28 | mediator complex subunit 28 | 0.029 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.027 | ||
| PICK1 | protein interacting with PRKCA 1 | 0.025 | ||
| PRKCD | protein kinase C, delta | 0.024 | ||
| ADRB1 | adrenergic, beta-1-, receptor | 0.024 | ||
| BACE1 | beta-site APP-cleaving enzyme 1 | 0.023 | ||
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.022 | ||
| NSF | N-ethylmaleimide-sensitive factor | 0.020 | ||
| PITPNM3 | PITPNM family member 3 | 0.018 | ||
| PRKCG | protein kinase C, gamma | 0.018 | ||
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.016 | ||
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A | 0.015 | ||
| MAP2 | microtubule-associated protein 2 | 0.015 | ||
| KCNA2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.015 | ||
| MAP1A | microtubule-associated protein 1A | 0.015 | ||
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.014 | ||
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 0.013 | ||
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 0.013 | ||
| KCNA5 | potassium voltage-gated channel, shaker-related subfamily, member 5 | 0.013 | ||
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.012 | ||
| ARHGAP32 | Rho GTPase activating protein 32 | 0.012 | ||
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.012 | ||
| PRLHR | prolactin releasing hormone receptor | 0.012 | ||
| GRIA3 | glutamate receptor, ionotrophic, AMPA 3 | 0.012 | ||
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.012 | ||
| HCN2 | hyperpolarization activated cyclic nucleotide-gated potassium channel 2 | 0.012 | ||
| SH2D1A | SH2 domain containing 1A | 0.012 | ||
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | 0.011 | ||
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.011 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.010 | ||
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta | 0.010 | ||
| KCNC1 | potassium voltage-gated channel, Shaw-related subfamily, member 1 | 0.010 |