IMP
Process View
negative regulation of cardioblast differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cardioblast differentiation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.988 | Fly | |
| CSNK1E | casein kinase 1, epsilon | 0.929 | ||
| RFWD2 | ring finger and WD repeat domain 2 | 0.803 | ||
| AXIN1 | axin 1 | 0.500 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.438 | ||
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.398 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.272 | Fly | |
| CREBBP | CREB binding protein | 0.254 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.248 | ||
| DUSP1 | dual specificity phosphatase 1 | 0.221 | ||
| TWIST2 | twist homolog 2 (Drosophila) | 0.213 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.184 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.177 | ||
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.142 | Fly | |
| REPS2 | RALBP1 associated Eps domain containing 2 | 0.138 | ||
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.127 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.125 | ||
| FAM110A | family with sequence similarity 110, member A | 0.124 | ||
| TRIM63 | tripartite motif containing 63 | 0.112 | ||
| JUN | jun proto-oncogene | 0.108 | ||
| CEP164 | centrosomal protein 164kDa | 0.104 | ||
| SP100 | SP100 nuclear antigen | 0.094 | ||
| JUP | junction plakoglobin | 0.081 | Fly | |
| SCNN1A | sodium channel, nonvoltage-gated 1 alpha | 0.068 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.068 | ||
| APC | adenomatous polyposis coli | 0.067 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.066 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.058 | ||
| LBX1 | ladybird homeobox 1 | 0.052 | ||
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.050 | ||
| PITX1 | paired-like homeodomain 1 | 0.049 | ||
| MCC | mutated in colorectal cancers | 0.047 | ||
| FZD8 | frizzled homolog 8 (Drosophila) | 0.047 | ||
| CRMP1 | collapsin response mediator protein 1 | 0.035 | ||
| WT1 | Wilms tumor 1 | 0.035 | ||
| C9orf100 | chromosome 9 open reading frame 100 | 0.034 | ||
| ZNF512B | zinc finger protein 512B | 0.033 | ||
| FOXD3 | forkhead box D3 | 0.033 | ||
| NPAS1 | neuronal PAS domain protein 1 | 0.030 | ||
| DSP | desmoplakin | 0.030 | ||
| AR | androgen receptor | 0.029 | ||
| FAM110C | family with sequence similarity 110, member C | 0.028 | ||
| SNIP1 | Smad nuclear interacting protein 1 | 0.026 | ||
| TIFA | TRAF-interacting protein with forkhead-associated domain | 0.025 | ||
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.024 | ||
| HES1 | hairy and enhancer of split 1, (Drosophila) | 0.024 | ||
| PYY | peptide YY | 0.024 | ||
| OCLN | occludin | 0.021 | ||
| NKD2 | naked cuticle homolog 2 (Drosophila) | 0.020 | ||
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.020 | ||
| AP1M1 | adaptor-related protein complex 1, mu 1 subunit | 0.020 | ||
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | 0.019 | ||
| IER2 | immediate early response 2 | 0.017 | ||
| FGF3 | fibroblast growth factor 3 | 0.017 | ||
| CDK10 | cyclin-dependent kinase 10 | 0.016 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.016 | ||
| NFIL3 | nuclear factor, interleukin 3 regulated | 0.016 | ||
| ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.015 | ||
| FZD2 | frizzled homolog 2 (Drosophila) | 0.015 | ||
| CSNK1D | casein kinase 1, delta | 0.015 | ||
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.014 | ||
| VASP | vasodilator-stimulated phosphoprotein | 0.014 | ||
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) | 0.014 | ||
| GBX2 | gastrulation brain homeobox 2 | 0.013 | ||
| DPPA2 | developmental pluripotency associated 2 | 0.013 | ||
| TWIST1 | twist homolog 1 (Drosophila) | 0.013 | ||
| DSG2 | desmoglein 2 | 0.013 | ||
| C16orf48 | chromosome 16 open reading frame 48 | 0.013 | ||
| ZNF408 | zinc finger protein 408 | 0.013 | ||
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.013 | ||
| GLIS2 | GLIS family zinc finger 2 | 0.013 | ||
| RUNX1 | runt-related transcription factor 1 | 0.012 | ||
| HOXC8 | homeobox C8 | 0.012 | ||
| FOXO1 | forkhead box O1 | 0.012 | ||
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.012 | ||
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.012 | ||
| SCAF1 | SR-related CTD-associated factor 1 | 0.012 | ||
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.012 | ||
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.011 | ||
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.011 | ||
| ARHGEF19 | Rho guanine nucleotide exchange factor (GEF) 19 | 0.011 | ||
| ESRRA | estrogen-related receptor alpha | 0.011 | ||
| POU4F3 | POU class 4 homeobox 3 | 0.011 | ||
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.011 | ||
| PER1 | period homolog 1 (Drosophila) | 0.011 | ||
| SFRP5 | secreted frizzled-related protein 5 | 0.011 | ||
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.011 | ||
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.010 |