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Homo sapiens

3 genes annotated in human

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activation of phospholipase d activity

GO:0031584

Any process that initiates the activity of inactive phospholipase D.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "activation of phospholipase d activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "activation of phospholipase d activity" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.997
ARFIP2	ADP-ribosylation factor interacting protein 2	0.856
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.817	Human
CCL2	chemokine (C-C motif) ligand 2	0.795	Human
CCL8	chemokine (C-C motif) ligand 8	0.676	Human
CCL4	chemokine (C-C motif) ligand 4	0.609	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.568
CCL5	chemokine (C-C motif) ligand 5	0.537
ARCN1	archain 1	0.372
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.368
CXCL13	chemokine (C-X-C motif) ligand 13	0.332
DPP4	dipeptidyl-peptidase 4	0.328
IDE	insulin-degrading enzyme	0.311
IL1B	interleukin 1, beta	0.271
VCAM1	vascular cell adhesion molecule 1	0.246
IL8	interleukin 8	0.242
IL6	interleukin 6 (interferon, beta 2)	0.168
CCR1	chemokine (C-C motif) receptor 1	0.148
CCL13	chemokine (C-C motif) ligand 13	0.125	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.118
RGS1	regulator of G-protein signaling 1	0.096
SEC22B	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)	0.087
CCL7	chemokine (C-C motif) ligand 7	0.087	Human
TMED2	transmembrane emp24 domain trafficking protein 2	0.078
IL10	interleukin 10	0.076
IL18RAP	interleukin 18 receptor accessory protein	0.072
CD83	CD83 molecule	0.068
SERP1	stress-associated endoplasmic reticulum protein 1	0.068
ZNF71	zinc finger protein 71	0.067
CCR7	chemokine (C-C motif) receptor 7	0.065
CCDC115	coiled-coil domain containing 115	0.057
IFNG	interferon, gamma	0.057
RAB11A	RAB11A, member RAS oncogene family	0.056
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.052
RAB1A	RAB1A, member RAS oncogene family	0.050
CYTH2	cytohesin 2	0.050
GNLY	granulysin	0.048
SELE	selectin E	0.047
ADAMDEC1	ADAM-like, decysin 1	0.044
SLAMF8	SLAM family member 8	0.044
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.043
IL2RB	interleukin 2 receptor, beta	0.043
FPR3	formyl peptide receptor 3	0.042
CXCL11	chemokine (C-X-C motif) ligand 11	0.042
TRAM1	translocation associated membrane protein 1	0.040
CXCL10	chemokine (C-X-C motif) ligand 10	0.037
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.037
CCL22	chemokine (C-C motif) ligand 22	0.037
C4orf14	chromosome 4 open reading frame 14	0.035
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	0.035
BET1	blocked early in transport 1 homolog (S. cerevisiae)	0.035
CXCL2	chemokine (C-X-C motif) ligand 2	0.035
CH25H	cholesterol 25-hydroxylase	0.034
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.034
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.032
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.032
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.032
SLAMF7	SLAM family member 7	0.031
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.031
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.030
WBP11	WW domain binding protein 11	0.028
ARRB1	arrestin, beta 1	0.027
VHL	von Hippel-Lindau tumor suppressor	0.027
INHBA	inhibin, beta A	0.027
SAR1B	SAR1 homolog B (S. cerevisiae)	0.026
TNF	tumor necrosis factor	0.026
CD163	CD163 molecule	0.026
SELP	selectin P (granule membrane protein 140kDa, antigen CD62)	0.025
TMEM50B	transmembrane protein 50B	0.024
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.024
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.023
CCR4	chemokine (C-C motif) receptor 4	0.023
C1QB	complement component 1, q subcomponent, B chain	0.023
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.023
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.022
CXCL5	chemokine (C-X-C motif) ligand 5	0.022
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.022
C12orf23	chromosome 12 open reading frame 23	0.022
CAPNS1	calpain, small subunit 1	0.022
CCL19	chemokine (C-C motif) ligand 19	0.021	Human
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.020
SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	0.020
GLT8D1	glycosyltransferase 8 domain containing 1	0.020
DARC	Duffy blood group, chemokine receptor	0.019
FKBP1A	FK506 binding protein 1A, 12kDa	0.019
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.019
CCL3	chemokine (C-C motif) ligand 3	0.019	Human
CFL1	cofilin 1 (non-muscle)	0.018
IL1RN	interleukin 1 receptor antagonist	0.018
CALM3	calmodulin 3 (phosphorylase kinase, delta)	0.018
APOC1	apolipoprotein C-I	0.018
NKG7	natural killer cell group 7 sequence	0.018
MSC	musculin	0.018
XCL2	chemokine (C motif) ligand 2	0.017
UBD	ubiquitin D	0.017
CD69	CD69 molecule	0.017
YIPF6	Yip1 domain family, member 6	0.017
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.016
MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.016
NUCB2	nucleobindin 2	0.016
AIG1	androgen-induced 1	0.016
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.016
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.016
CCR3	chemokine (C-C motif) receptor 3	0.016
RGS16	regulator of G-protein signaling 16	0.015
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.015
TMEM106A	transmembrane protein 106A	0.015
WRB	tryptophan rich basic protein	0.015
CRIPT	cysteine-rich PDZ-binding protein	0.015
NMT2	N-myristoyltransferase 2	0.014
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.014
SAR1A	SAR1 homolog A (S. cerevisiae)	0.014
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.014
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.014
IL32	interleukin 32	0.013
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.013
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.013
OASL	2'-5'-oligoadenylate synthetase-like	0.013
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.013
CCL21	chemokine (C-C motif) ligand 21	0.013
CALU	calumenin	0.013
GOLGA5	golgin A5	0.013
IL7R	interleukin 7 receptor	0.013
ERLEC1	endoplasmic reticulum lectin 1	0.013
ADIPOR1	adiponectin receptor 1	0.013
TRAF1	TNF receptor-associated factor 1	0.013
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.013
IL1A	interleukin 1, alpha	0.013
CXCR6	chemokine (C-X-C motif) receptor 6	0.013
UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	0.012
AGA	aspartylglucosaminidase	0.012
SRGN	serglycin	0.012
MPV17	MpV17 mitochondrial inner membrane protein	0.012
C1QA	complement component 1, q subcomponent, A chain	0.012
CCL23	chemokine (C-C motif) ligand 23	0.012	Human
TRIM55	tripartite motif containing 55	0.012
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.012
SELT	selenoprotein T	0.012
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.012
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.012
TMED7	transmembrane emp24 protein transport domain containing 7	0.012
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.012
MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like	0.012
CNIH	cornichon homolog (Drosophila)	0.011
EGFL6	EGF-like-domain, multiple 6	0.011
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.011
YIPF5	Yip1 domain family, member 5	0.011
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.011
TRAPPC1	trafficking protein particle complex 1	0.011
PRF1	perforin 1 (pore forming protein)	0.011
CXCR3	chemokine (C-X-C motif) receptor 3	0.011
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.011
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.011
SCOC	short coiled-coil protein	0.011
BAD	BCL2-associated agonist of cell death	0.011
NNMT	nicotinamide N-methyltransferase	0.010
IL1R2	interleukin 1 receptor, type II	0.010
TMCO1	transmembrane and coiled-coil domains 1	0.010
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.010
LAMP3	lysosomal-associated membrane protein 3	0.010
CCL20	chemokine (C-C motif) ligand 20	0.010	Human
MSR1	macrophage scavenger receptor 1	0.010
C3	complement component 3	0.010
OSTC	oligosaccharyltransferase complex subunit	0.010
PDPN	podoplanin	0.010
MARCO	macrophage receptor with collagenous structure	0.010
IDO1	indoleamine 2,3-dioxygenase 1	0.010
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.010
VCAN	versican	0.010