IMP

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Homo sapiens

3 genes annotated in human

skeletal muscle thin filament assembly

The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "skeletal muscle thin filament assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "skeletal muscle thin filament assembly" (in gray)

Name	Description	Probability	Func Analog Organism
ACTB	actin, beta	1.000	Human
TRIM63	tripartite motif containing 63	1.000
CFL1	cofilin 1 (non-muscle)	0.999
TTN	titin	0.998
ACTG1	actin, gamma 1	0.995	Human
NEB	nebulin	0.993
MYOZ1	myozenin 1	0.988
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.945
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.928
ACTN2	actinin, alpha 2	0.902
MYH9	myosin, heavy chain 9, non-muscle	0.878
ACTA1	actin, alpha 1, skeletal muscle	0.842
CFL2	cofilin 2 (muscle)	0.772
ACTN1	actinin, alpha 1	0.735
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.581
DES	desmin	0.581
CAPN3	calpain 3, (p94)	0.565
TPM4	tropomyosin 4	0.407
TNNC1	troponin C type 1 (slow)	0.383
TCAP	titin-cap (telethonin)	0.380
TPM1	tropomyosin 1 (alpha)	0.329
MYH11	myosin, heavy chain 11, smooth muscle	0.288
ACTC1	actin, alpha, cardiac muscle 1	0.251	Human
CNN2	calponin 2	0.209
MRPL41	mitochondrial ribosomal protein L41	0.199
OBSL1	obscurin-like 1	0.190
TNNI2	troponin I type 2 (skeletal, fast)	0.183
HNF4A	hepatocyte nuclear factor 4, alpha	0.180
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.165
FLNA	filamin A, alpha	0.145
ACTA2	actin, alpha 2, smooth muscle, aorta	0.125	Human
DSTN	destrin (actin depolymerizing factor)	0.110
HSPH1	heat shock 105kDa/110kDa protein 1	0.088
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.088
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.076
PFN1	profilin 1	0.072
TNNI1	troponin I type 1 (skeletal, slow)	0.066
TNNI3	troponin I type 3 (cardiac)	0.065
CNN1	calponin 1, basic, smooth muscle	0.064
TPM2	tropomyosin 2 (beta)	0.063
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.062
TUBA1B	tubulin, alpha 1b	0.059
GSN	gelsolin	0.058
TMSB10	thymosin beta 10	0.056
ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.056
TUBA1C	tubulin, alpha 1c	0.055
ZYX	zyxin	0.050
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.050
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.047
FLNC	filamin C, gamma	0.040
ANK1	ankyrin 1, erythrocytic	0.039
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.037
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.036
MYPN	myopalladin	0.036
CKM	creatine kinase, muscle	0.036
HSPA8	heat shock 70kDa protein 8	0.034
ENO3	enolase 3 (beta, muscle)	0.033
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.031
PPP5C	protein phosphatase 5, catalytic subunit	0.031
MYL9	myosin, light chain 9, regulatory	0.030
CORO1C	coronin, actin binding protein, 1C	0.030
MYOZ2	myozenin 2	0.029
ACTN3	actinin, alpha 3	0.029
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.028
CTBP2	C-terminal binding protein 2	0.028
CSRP1	cysteine and glycine-rich protein 1	0.027
PDPK1	3-phosphoinositide dependent protein kinase-1	0.026
LDB3	LIM domain binding 3	0.025
FBXO25	F-box protein 25	0.024
TNNT1	troponin T type 1 (skeletal, slow)	0.024
TNNC2	troponin C type 2 (fast)	0.024
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.023
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.023
VASP	vasodilator-stimulated phosphoprotein	0.022
RHOA	ras homolog gene family, member A	0.022
PKM2	pyruvate kinase, muscle	0.021
MYBPC3	myosin binding protein C, cardiac	0.021
ACTG2	actin, gamma 2, smooth muscle, enteric	0.020	Human
TNNT3	troponin T type 3 (skeletal, fast)	0.020
FN1	fibronectin 1	0.020
TAGLN2	transgelin 2	0.020
LMCD1	LIM and cysteine-rich domains 1	0.020
TAGLN	transgelin	0.020
NCF1	neutrophil cytosolic factor 1	0.019
MSN	moesin	0.019
NOMO1	NODAL modulator 1	0.019
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.018
COTL1	coactosin-like 1 (Dictyostelium)	0.018
CALD1	caldesmon 1	0.018
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.018
SMPX	small muscle protein, X-linked	0.018
DCAF6	DDB1 and CUL4 associated factor 6	0.017
GFM1	G elongation factor, mitochondrial 1	0.017
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.017
MYOM2	myomesin (M-protein) 2, 165kDa	0.016
GMEB1	glucocorticoid modulatory element binding protein 1	0.016
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.016
VCL	vinculin	0.015
CCDC115	coiled-coil domain containing 115	0.015
MYBPH	myosin binding protein H	0.015
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.014
MYBPC2	myosin binding protein C, fast type	0.014
ACTN4	actinin, alpha 4	0.014
OSTF1	osteoclast stimulating factor 1	0.014
TRIM55	tripartite motif containing 55	0.014
REPS2	RALBP1 associated Eps domain containing 2	0.014
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.014
TNNI3K	TNNI3 interacting kinase	0.013
KBTBD10	kelch repeat and BTB (POZ) domain containing 10	0.013
GAB2	GRB2-associated binding protein 2	0.013
ANKRD23	ankyrin repeat domain 23	0.013
LY6G6F	lymphocyte antigen 6 complex, locus G6F	0.013
TRIM54	tripartite motif containing 54	0.013
MYBPC1	myosin binding protein C, slow type	0.013
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.012
VAV3	vav 3 guanine nucleotide exchange factor	0.012
HNF1A	HNF1 homeobox A	0.012
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.012
PDLIM7	PDZ and LIM domain 7 (enigma)	0.012
SYNPO2L	synaptopodin 2-like	0.012
SVIL	supervillin	0.011
PYGM	phosphorylase, glycogen, muscle	0.011
LIMK1	LIM domain kinase 1	0.011
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.011
PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	0.010
FHL2	four and a half LIM domains 2	0.010
MIB2	mindbomb homolog 2 (Drosophila)	0.010
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.010
WDR1	WD repeat domain 1	0.010	Worm
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.010
PDLIM3	PDZ and LIM domain 3	0.010
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.010
PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.010