IMP
Process View
non canonical wnt signaling pathway via jnk cascade
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade.
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Click on a gene's description to view its network relationships with genes known to be involved in "non canonical wnt signaling pathway via jnk cascade"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.964 | ||
| ZNF512B | zinc finger protein 512B | 0.878 | ||
| WT1 | Wilms tumor 1 | 0.610 | ||
| CSNK1E | casein kinase 1, epsilon | 0.547 | ||
| CEP164 | centrosomal protein 164kDa | 0.506 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.465 | ||
| LRRK2 | leucine-rich repeat kinase 2 | 0.445 | ||
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.250 | ||
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.184 | ||
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.140 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.109 | ||
| NDP | Norrie disease (pseudoglioma) | 0.106 | ||
| SFRP1 | secreted frizzled-related protein 1 | 0.093 | ||
| MXRA5 | matrix-remodelling associated 5 | 0.088 | ||
| RGS2 | regulator of G-protein signaling 2, 24kDa | 0.073 | ||
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | 0.061 | ||
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.054 | ||
| MYST2 | MYST histone acetyltransferase 2 | 0.050 | ||
| AXIN1 | axin 1 | 0.048 | ||
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.045 | ||
| EHF | ets homologous factor | 0.041 | ||
| GPR124 | G protein-coupled receptor 124 | 0.041 | ||
| OGN | osteoglycin | 0.038 | ||
| FOXF2 | forkhead box F2 | 0.038 | ||
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.037 | ||
| OMD | osteomodulin | 0.034 | ||
| FZD7 | frizzled homolog 7 (Drosophila) | 0.034 | ||
| GDF10 | growth differentiation factor 10 | 0.027 | ||
| KLHL12 | kelch-like 12 (Drosophila) | 0.026 | ||
| THBS2 | thrombospondin 2 | 0.026 | ||
| SFRP4 | secreted frizzled-related protein 4 | 0.025 | Human | |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.024 | ||
| TNFAIP8L1 | tumor necrosis factor, alpha-induced protein 8-like 1 | 0.023 | ||
| BAHD1 | bromo adjacent homology domain containing 1 | 0.023 | ||
| ITIH5 | inter-alpha (globulin) inhibitor H5 | 0.022 | ||
| CSNK1D | casein kinase 1, delta | 0.021 | ||
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.020 | ||
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.020 | ||
| PDGFC | platelet derived growth factor C | 0.019 | ||
| BMP4 | bone morphogenetic protein 4 | 0.019 | ||
| RAI2 | retinoic acid induced 2 | 0.018 | ||
| SDC2 | syndecan 2 | 0.018 | ||
| ZBTB48 | zinc finger and BTB domain containing 48 | 0.018 | ||
| LAMA2 | laminin, alpha 2 | 0.018 | ||
| ZNF423 | zinc finger protein 423 | 0.018 | ||
| LMO4 | LIM domain only 4 | 0.018 | ||
| C16orf48 | chromosome 16 open reading frame 48 | 0.018 | ||
| PRPF3 | PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) | 0.018 | ||
| OLFML3 | olfactomedin-like 3 | 0.018 | ||
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.017 | ||
| GPC4 | glypican 4 | 0.017 | ||
| FZD1 | frizzled homolog 1 (Drosophila) | 0.017 | Human | |
| LHFP | lipoma HMGIC fusion partner | 0.017 | ||
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.016 | ||
| LUM | lumican | 0.016 | ||
| COL8A1 | collagen, type VIII, alpha 1 | 0.016 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.016 | ||
| DPY19L4 | dpy-19-like 4 (C. elegans) | 0.016 | ||
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.015 | ||
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.015 | ||
| TRIL | TLR4 interactor with leucine-rich repeats | 0.015 | ||
| LRRC17 | leucine rich repeat containing 17 | 0.015 | ||
| PTN | pleiotrophin | 0.015 | ||
| MFAP5 | microfibrillar associated protein 5 | 0.015 | ||
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.015 | ||
| PRELP | proline/arginine-rich end leucine-rich repeat protein | 0.015 | ||
| SPARCL1 | SPARC-like 1 (hevin) | 0.015 | ||
| TCF7L1 | transcription factor 7-like 1 (T-cell specific, HMG-box) | 0.015 | ||
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.014 | ||
| FRZB | frizzled-related protein | 0.014 | Human | |
| C7 | complement component 7 | 0.014 | ||
| BMP7 | bone morphogenetic protein 7 | 0.014 | ||
| PEG10 | paternally expressed 10 | 0.014 | ||
| KCNE4 | potassium voltage-gated channel, Isk-related family, member 4 | 0.014 | ||
| ASPN | asporin | 0.014 | ||
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.013 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.013 | ||
| ZNF408 | zinc finger protein 408 | 0.013 | ||
| CASQ2 | calsequestrin 2 (cardiac muscle) | 0.013 | ||
| CAPN6 | calpain 6 | 0.013 | ||
| SMAD1 | SMAD family member 1 | 0.013 | ||
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.013 | ||
| FBLN1 | fibulin 1 | 0.013 | ||
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.013 | ||
| ANGPT1 | angiopoietin 1 | 0.012 | ||
| MSX1 | msh homeobox 1 | 0.012 | ||
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.012 | Mouse | |
| PDGFD | platelet derived growth factor D | 0.012 | ||
| JAG1 | jagged 1 | 0.012 | ||
| THBS4 | thrombospondin 4 | 0.012 | ||
| RAB5B | RAB5B, member RAS oncogene family | 0.012 | ||
| LMOD1 | leiomodin 1 (smooth muscle) | 0.012 | ||
| CTSK | cathepsin K | 0.012 | ||
| VGLL3 | vestigial like 3 (Drosophila) | 0.012 | ||
| POSTN | periostin, osteoblast specific factor | 0.012 | ||
| COL14A1 | collagen, type XIV, alpha 1 | 0.012 | ||
| SOX9 | SRY (sex determining region Y)-box 9 | 0.012 | ||
| MFAP4 | microfibrillar-associated protein 4 | 0.012 | ||
| AXIN2 | axin 2 | 0.012 | ||
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) | 0.011 | ||
| PARM1 | prostate androgen-regulated mucin-like protein 1 | 0.011 | ||
| DACT1 | dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) | 0.011 | ||
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.011 | ||
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.011 | ||
| ITGA8 | integrin, alpha 8 | 0.011 | ||
| FAT4 | FAT tumor suppressor homolog 4 (Drosophila) | 0.011 | ||
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.011 | ||
| DIDO1 | death inducer-obliterator 1 | 0.011 | ||
| KCNS3 | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | 0.011 | ||
| PITX1 | paired-like homeodomain 1 | 0.011 | ||
| CCDC92 | coiled-coil domain containing 92 | 0.011 | ||
| NKD2 | naked cuticle homolog 2 (Drosophila) | 0.010 | ||
| DOK5 | docking protein 5 | 0.010 | ||
| FOXQ1 | forkhead box Q1 | 0.010 | ||
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.010 | ||
| BICC1 | bicaudal C homolog 1 (Drosophila) | 0.010 | ||
| APOD | apolipoprotein D | 0.010 | ||
| COL21A1 | collagen, type XXI, alpha 1 | 0.010 | ||
| SOX17 | SRY (sex determining region Y)-box 17 | 0.010 | ||
| INHBB | inhibin, beta B | 0.010 | ||
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.010 | ||
| NOTCH2 | notch 2 | 0.010 |