IMP
Process View
macrophage activation involved in immune response
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
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Click on a gene's description to view its network relationships with genes known to be involved in "macrophage activation involved in immune response"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.914 | ||
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.861 | ||
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.795 | ||
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 0.585 | ||
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.471 | ||
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.455 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.351 | ||
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.296 | ||
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.178 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.106 | ||
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.099 | ||
| SH3BP2 | SH3-domain binding protein 2 | 0.089 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.080 | ||
| BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.070 | ||
| CD247 | CD247 molecule | 0.069 | ||
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.069 | ||
| SYK | spleen tyrosine kinase | 0.068 | Mouse | |
| SIRPB1 | signal-regulatory protein beta 1 | 0.067 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.064 | ||
| LCK | lymphocyte-specific protein tyrosine kinase | 0.059 | ||
| LAT | linker for activation of T cells | 0.044 | ||
| MYO9B | myosin IXB | 0.034 | ||
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.032 | ||
| PTPRC | protein tyrosine phosphatase, receptor type, C | 0.029 | ||
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.028 | ||
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.025 | ||
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.021 | ||
| C4BPA | complement component 4 binding protein, alpha | 0.019 | ||
| EGFR | epidermal growth factor receptor | 0.018 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.018 | ||
| ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.018 | ||
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.017 | ||
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.016 | ||
| CD14 | CD14 molecule | 0.015 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.015 | ||
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.015 | ||
| C19orf6 | chromosome 19 open reading frame 6 | 0.014 | ||
| EZR | ezrin | 0.014 | ||
| LST1 | leukocyte specific transcript 1 | 0.013 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.012 | ||
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.012 | ||
| SPI1 | spleen focus forming virus (SFFV) proviral integration oncogene spi1 | 0.011 | ||
| LAPTM5 | lysosomal protein transmembrane 5 | 0.011 | ||
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.011 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.011 | ||
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.010 | ||
| SH2B2 | SH2B adaptor protein 2 | 0.010 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.010 |