IMP

Process View

Homo sapiens

11 genes annotated in human

urate metabolic process

The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "urate metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "urate metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
PLAUR	plasminogen activator, urokinase receptor	0.600
BHLHE40	basic helix-loop-helix family, member e40	0.593
PGK1	phosphoglycerate kinase 1	0.411
SLC28A1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.397
DAXX	death-domain associated protein	0.360
SLC6A12	solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12	0.252
SLC34A1	solute carrier family 34 (sodium phosphate), member 1	0.248
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.234
ODC1	ornithine decarboxylase 1	0.226
LDHA	lactate dehydrogenase A	0.207
GCK	glucokinase (hexokinase 4)	0.186
UCK2	uridine-cytidine kinase 2	0.178
CKS2	CDC28 protein kinase regulatory subunit 2	0.136
HPRT1	hypoxanthine phosphoribosyltransferase 1	0.118
SLC17A3	solute carrier family 17 (sodium phosphate), member 3	0.117
PRODH2	proline dehydrogenase (oxidase) 2	0.087
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.087
TFRC	transferrin receptor (p90, CD71)	0.086
HPD	4-hydroxyphenylpyruvate dioxygenase	0.073
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.068
ADM	adrenomedullin	0.064
GLA	galactosidase, alpha	0.057
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.054	Human
C8A	complement component 8, alpha polypeptide	0.053
G6PC	glucose-6-phosphatase, catalytic subunit	0.053
SLC13A3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3	0.053
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.050
SLC22A8	solute carrier family 22 (organic anion transporter), member 8	0.050	Human
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.049	Human
GLYAT	glycine-N-acyltransferase	0.046
UPP1	uridine phosphorylase 1	0.045
PRPS1	phosphoribosyl pyrophosphate synthetase 1	0.043
SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1	0.041
CYP2A6	cytochrome P450, family 2, subfamily A, polypeptide 6	0.040
AQP2	aquaporin 2 (collecting duct)	0.040
HABP2	hyaluronan binding protein 2	0.038
GMPS	guanine monphosphate synthetase	0.038
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.037
PRPS2	phosphoribosyl pyrophosphate synthetase 2	0.035	Human
ENO1	enolase 1, (alpha)	0.031
SLC12A3	solute carrier family 12 (sodium/chloride transporters), member 3	0.030
HRG	histidine-rich glycoprotein	0.029
GGH	gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)	0.029
KNG1	kininogen 1	0.029
HAO2	hydroxyacid oxidase 2 (long chain)	0.028
NFIL3	nuclear factor, interleukin 3 regulated	0.028
DPYS	dihydropyrimidinase	0.026
SLC22A2	solute carrier family 22 (organic cation transporter), member 2	0.026	Human
TMEM97	transmembrane protein 97	0.026
TMX1	thioredoxin-related transmembrane protein 1	0.025
CST9L	cystatin 9-like	0.025
CA5A	carbonic anhydrase VA, mitochondrial	0.024
PAH	phenylalanine hydroxylase	0.023
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.023
DAO	D-amino-acid oxidase	0.022
SLC22A6	solute carrier family 22 (organic anion transporter), member 6	0.022	Human
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.022
PLAU	plasminogen activator, urokinase	0.021
PRPSAP1	phosphoribosyl pyrophosphate synthetase-associated protein 1	0.021
AGXT	alanine-glyoxylate aminotransferase	0.021
PKLR	pyruvate kinase, liver and RBC	0.021
SLC17A2	solute carrier family 17 (sodium phosphate), member 2	0.020	Human
NDRG1	N-myc downstream regulated 1	0.020
XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	0.020
PCNA	proliferating cell nuclear antigen	0.019
TM4SF5	transmembrane 4 L six family member 5	0.019
PRC1	protein regulator of cytokinesis 1	0.019
STC1	stanniocalcin 1	0.018
ALDOB	aldolase B, fructose-bisphosphate	0.018
BHMT	betaine--homocysteine S-methyltransferase	0.018
C9orf167	chromosome 9 open reading frame 167	0.018
PLG	plasminogen	0.018
AK2	adenylate kinase 2	0.018
PDZK1	PDZ domain containing 1	0.017
TFDP1	transcription factor Dp-1	0.017
CASR	calcium-sensing receptor	0.017
C9	complement component 9	0.017
TREM1	triggering receptor expressed on myeloid cells 1	0.017
RDH16	retinol dehydrogenase 16 (all-trans)	0.016
MST4	serine/threonine protein kinase MST4	0.016
IER3	immediate early response 3	0.016
GRPEL1	GrpE-like 1, mitochondrial (E. coli)	0.016
XDH	xanthine dehydrogenase	0.016
VDAC1	voltage-dependent anion channel 1	0.016
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.016
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.016
PGAM1	phosphoglycerate mutase 1 (brain)	0.015
CDHR2	cadherin-related family member 2	0.015
AIRE	autoimmune regulator	0.015
ADH6	alcohol dehydrogenase 6 (class V)	0.015
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.015
AQP7	aquaporin 7	0.014
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.014
SLC35F2	solute carrier family 35, member F2	0.014
C8B	complement component 8, beta polypeptide	0.014
PGLYRP4	peptidoglycan recognition protein 4	0.014
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.014
SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.014
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.014
IL8	interleukin 8	0.014
VIL1	villin 1	0.014
HAO1	hydroxyacid oxidase (glycolate oxidase) 1	0.013
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.013	Human
KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1	0.013
AFM	afamin	0.013
HNF1B	HNF1 homeobox B	0.013
MPHOSPH6	M-phase phosphoprotein 6	0.013
RHBG	Rh family, B glycoprotein (gene/pseudogene)	0.012
MCM6	minichromosome maintenance complex component 6	0.012
UPB1	ureidopropionase, beta	0.012
A1CF	APOBEC1 complementation factor	0.012
FTCD	formiminotransferase cyclodeaminase	0.012
CDK2	cyclin-dependent kinase 2	0.012
C7orf68	chromosome 7 open reading frame 68	0.012
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.011
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
SPP2	secreted phosphoprotein 2, 24kDa	0.011
MASP2	mannan-binding lectin serine peptidase 2	0.011
PROZ	protein Z, vitamin K-dependent plasma glycoprotein	0.011
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.011
SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	0.010
ADORA2B	adenosine A2b receptor	0.010
ALDOA	aldolase A, fructose-bisphosphate	0.010
SFXN1	sideroflexin 1	0.010
NAT8B	N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)	0.010
CRP	C-reactive protein, pentraxin-related	0.010
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.010
CAMK2A	calcium/calmodulin-dependent protein kinase II alpha	0.010