IMP

Process View

Homo sapiens

9 genes annotated in human

cortical actin cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cortical actin cytoskeleton organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cortical actin cytoskeleton organization" (in gray)

Name	Description	Probability	Func Analog Organism
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.832	Human Fly
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.782	Human Fly
RHOA	ras homolog gene family, member A	0.506	Fly
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.483
GAS7	growth arrest-specific 7	0.336
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.292
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.253
SORBS3	sorbin and SH3 domain containing 3	0.238
PFN1	profilin 1	0.182
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.160
ANKRD28	ankyrin repeat domain 28	0.106
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.096
ZYX	zyxin	0.076
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.072	Yeast
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.070
HTT	huntingtin	0.066
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.066
GDA	guanine deaminase	0.064
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.052
PPP6C	protein phosphatase 6, catalytic subunit	0.048	Worm
MSN	moesin	0.048	Fly
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.046	Fly
EZR	ezrin	0.046	Fly
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.044	Fly
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.036
ACTB	actin, beta	0.035
WASF1	WAS protein family, member 1	0.035	Fly
PDIA3	protein disulfide isomerase family A, member 3	0.033
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.033
MYH9	myosin, heavy chain 9, non-muscle	0.028
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.027
CFL1	cofilin 1 (non-muscle)	0.026
TAGLN2	transgelin 2	0.026
PDPK1	3-phosphoinositide dependent protein kinase-1	0.026
MYO9B	myosin IXB	0.024
SOS1	son of sevenless homolog 1 (Drosophila)	0.024
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.023
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.023
DNM1	dynamin 1	0.022	Fly
CAPNS1	calpain, small subunit 1	0.022
RHOC	ras homolog gene family, member C	0.022	Fly
DIAPH1	diaphanous homolog 1 (Drosophila)	0.022
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.022
TTN	titin	0.022
STRN	striatin, calmodulin binding protein	0.022
ADAM17	ADAM metallopeptidase domain 17	0.021
ARHGAP1	Rho GTPase activating protein 1	0.020
RAB1A	RAB1A, member RAS oncogene family	0.020
PICALM	phosphatidylinositol binding clathrin assembly protein	0.020
ABI2	abl-interactor 2	0.020	Fly
TRIM63	tripartite motif containing 63	0.019
ARFIP2	ADP-ribosylation factor interacting protein 2	0.018
FKBP1A	FK506 binding protein 1A, 12kDa	0.018
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.018
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.018
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.015
FLNA	filamin A, alpha	0.015
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.015
CD44	CD44 molecule (Indian blood group)	0.015
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.014
NCF2	neutrophil cytosolic factor 2	0.014
MYPN	myopalladin	0.014
EHD1	EH-domain containing 1	0.013
VASP	vasodilator-stimulated phosphoprotein	0.013
CNN2	calponin 2	0.013
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.013
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.013
TPM4	tropomyosin 4	0.012
DNM2	dynamin 2	0.012	Fly
YAP1	Yes-associated protein 1	0.012
GRB2	growth factor receptor-bound protein 2	0.012
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.012
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.012
STK24	serine/threonine kinase 24	0.011
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.011
AMPH	amphiphysin	0.011
EMP3	epithelial membrane protein 3	0.011
ATP13A2	ATPase type 13A2	0.011
COTL1	coactosin-like 1 (Dictyostelium)	0.011
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.011
RHOG	ras homolog gene family, member G (rho G)	0.011	Human
SPAG9	sperm associated antigen 9	0.011
CORO1A	coronin, actin binding protein, 1A	0.010
CRMP1	collapsin response mediator protein 1	0.010
FMR1	fragile X mental retardation 1	0.010
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.010	Human Fly