IMP

Process View

Homo sapiens

12 genes annotated in human

Multi-species View

spindle localization

GO:0051653

Any process in which is the spindle is transported to, and/or maintained in, a specific location.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "spindle localization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "spindle localization" (in gray)

Name	Description	Probability	Func Analog Organism
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.149	Worm
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.129
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.117
APC	adenomatous polyposis coli	0.102
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.074
ANKRD28	ankyrin repeat domain 28	0.070
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.067	Worm
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.065	Worm
KIF23	kinesin family member 23	0.058
GDA	guanine deaminase	0.044
GSK3B	glycogen synthase kinase 3 beta	0.043	Worm
GRB2	growth factor receptor-bound protein 2	0.040
MARK2	MAP/microtubule affinity-regulating kinase 2	0.039
CNOT6	CCR4-NOT transcription complex, subunit 6	0.038
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.036	Worm
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.034
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.027
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.027	Worm
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.026
PRKCZ	protein kinase C, zeta	0.026
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.025
AXIN1	axin 1	0.025
NCAPG	non-SMC condensin I complex, subunit G	0.024
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.021
FLNA	filamin A, alpha	0.021
ZBED1	zinc finger, BED-type containing 1	0.020
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.018	Worm
PRC1	protein regulator of cytokinesis 1	0.018
KIF5B	kinesin family member 5B	0.018	Worm
IQGAP1	IQ motif containing GTPase activating protein 1	0.017
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.017
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.017
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.016
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.016
KIF1B	kinesin family member 1B	0.015
CAPNS1	calpain, small subunit 1	0.015
CD44	CD44 molecule (Indian blood group)	0.015
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.015
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.015	Worm Fly
CSNK1E	casein kinase 1, epsilon	0.015
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.015
WIPF1	WAS/WASL interacting protein family, member 1	0.014
RHOA	ras homolog gene family, member A	0.014
GPSM2	G-protein signaling modulator 2	0.014	Mouse Fly
LRRK2	leucine-rich repeat kinase 2	0.013
PPP6R2	protein phosphatase 6, regulatory subunit 2	0.013
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.013	Worm
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.013
CKAP5	cytoskeleton associated protein 5	0.012
BTRC	beta-transducin repeat containing	0.012
SPC24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.012
NCF2	neutrophil cytosolic factor 2	0.012
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.011
NUP62	nucleoporin 62kDa	0.011
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.010
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.010
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.010