IMP

Process View

Homo sapiens

11 genes annotated in human

positive regulation of fatty acid metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of fatty acid metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of fatty acid metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	0.960
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.940	Yeast
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.843	Rat
PEX19	peroxisomal biogenesis factor 19	0.684
NOXA1	NADPH oxidase activator 1	0.516
GRB10	growth factor receptor-bound protein 10	0.451
PPARG	peroxisome proliferator-activated receptor gamma	0.427	Rat
HNF4A	hepatocyte nuclear factor 4, alpha	0.369	Rat
IGF1R	insulin-like growth factor 1 receptor	0.364
RARA	retinoic acid receptor, alpha	0.313
RXRA	retinoid X receptor, alpha	0.303
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.257
SMAD4	SMAD family member 4	0.212
ESRRG	estrogen-related receptor gamma	0.190
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.178	Yeast
NCF1	neutrophil cytosolic factor 1	0.171
FBXL15	F-box and leucine-rich repeat protein 15	0.160
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.158
NCOR2	nuclear receptor corepressor 2	0.137
SETD8	SET domain containing (lysine methyltransferase) 8	0.108
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.105
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.101
PRKCZ	protein kinase C, zeta	0.091	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.089
ALB	albumin	0.068
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.066
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.061	Yeast
NCOA1	nuclear receptor coactivator 1	0.055
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.054
HP	haptoglobin	0.053
SUFU	suppressor of fused homolog (Drosophila)	0.051
SQSTM1	sequestosome 1	0.050
CDCP1	CUB domain containing protein 1	0.044
PROX1	prospero homeobox 1	0.036
PEX14	peroxisomal biogenesis factor 14	0.034
APOC1	apolipoprotein C-I	0.033
IRS1	insulin receptor substrate 1	0.030
PEX11B	peroxisomal biogenesis factor 11 beta	0.030
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.029
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.027
RUNX1	runt-related transcription factor 1	0.027
EDF1	endothelial differentiation-related factor 1	0.026
APOA2	apolipoprotein A-II	0.025
CYBA	cytochrome b-245, alpha polypeptide	0.024
APOC3	apolipoprotein C-III	0.024
SH2B1	SH2B adaptor protein 1	0.024
APOE	apolipoprotein E	0.024
PDX1	pancreatic and duodenal homeobox 1	0.023
ANKRD13A	ankyrin repeat domain 13A	0.023
PGRMC1	progesterone receptor membrane component 1	0.023
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.022
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.021
APOA1	apolipoprotein A-I	0.020	Human
SH3RF1	SH3 domain containing ring finger 1	0.019
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.019
GATA2	GATA binding protein 2	0.018
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.017
BAD	BCL2-associated agonist of cell death	0.017
XPO7	exportin 7	0.017
PEX3	peroxisomal biogenesis factor 3	0.017
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.016
PEX16	peroxisomal biogenesis factor 16	0.016
MED25	mediator complex subunit 25	0.016
TSC22D1	TSC22 domain family, member 1	0.016
CREBBP	CREB binding protein	0.016
TRIM9	tripartite motif containing 9	0.016
IRS2	insulin receptor substrate 2	0.015
GLI1	GLI family zinc finger 1	0.015
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.015
LCAT	lecithin-cholesterol acyltransferase	0.015
CCL14	chemokine (C-C motif) ligand 14	0.014
SREBF2	sterol regulatory element binding transcription factor 2	0.014
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.014	Yeast
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.014
PDPK1	3-phosphoinositide dependent protein kinase-1	0.014
PRKCB	protein kinase C, beta	0.013
SH3KBP1	SH3-domain kinase binding protein 1	0.013
PEX26	peroxisomal biogenesis factor 26	0.013
MYOD1	myogenic differentiation 1	0.013
OPTN	optineurin	0.013
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.013
PXMP2	peroxisomal membrane protein 2, 22kDa	0.012
JUN	jun proto-oncogene	0.012
APOB	apolipoprotein B (including Ag(x) antigen)	0.011
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.011
F11R	F11 receptor	0.011
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.011
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.010	Yeast
PICK1	protein interacting with PRKCA 1	0.010
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.010	Yeast
STAT5B	signal transducer and activator of transcription 5B	0.010
TRAF4	TNF receptor-associated factor 4	0.010
PRKCA	protein kinase C, alpha	0.010